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Number of items at this level: 535.

2024

Parakkatel, Dixy; Ruprecht, Nico; von Tengg-Kobligk, Hendrik; Engelhardt, Britta; Heverhagen, Johannes (June 2024). Investigating the role of peripheral blood mononuclear cells in gadolinium deposition in the brain (Unpublished). In: Swiss Congress of Radiology 2024 (SCR'24). Geneva. June 2024.

Sáinz-Jaspeado, Miguel; Proulx, Steven T; Ring, Sarah; Richards, Mark; Martinsson, Pernilla; Li, Xiujuan; Claesson-Welsh, Lena; Ulvmar, Maria H; Jin, Yi (2024). VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis. Life science alliance, 7(3) EMBO Press 10.26508/lsa.202302168

Seillier, Célia; Lesec, Léonie; Hélie, Pauline; Marie, Charlotte; Vivien, Denis; Docagne, Fabian; Le Mauff, Brigitte; Toutirais, Olivier (2024). Tissue-plasminogen activator effects on the phenotype of splenic myeloid cells in acute inflammation. Journal of inflammation, 21(4) BioMed Central 10.1186/s12950-024-00375-0

Denes, Adam; Hansen, Cathrin E; Oezorhan, Uemit; Figuerola, Sara; de Vries, Helga E; Sorokin, Lydia; Planas, Anna M; Engelhardt, Britta; Schwaninger, Markus (2024). Endothelial cells and macrophages as allies in the healthy and diseased brain. Acta neuropathologica, 147(38) Springer-Verlag 10.1007/s00401-024-02695-0

Kelly, Louise; Brown, Christopher; Michalik, Daniel; Hawkes, Cheryl A; Aldea, Roxana; Agarwal, Nivedita; Salib, Rami; Alzetani, Aiman; Ethell, Douglas W; Counts, Scott E; de Leon, Mony; Fossati, Silvia; Koronyo-Hamaoui, Maya; Piazza, Fabrizio; Rich, Steven A; Wolters, Frank J; Snyder, Heather; Ismail, Ozama; Elahi, Fanny; Proulx, Steven T; ... (2024). Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA), updates in 2022-2023. Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease: Opportunities for therapy. Alzheimer's & dementia : the journal of the Alzheimer's Association, 20(2), pp. 1421-1435. 10.1002/alz.13512

McCloskey, Molly C; Kasap, Pelin; Trempel, Michelle; Widom, Louis P; Kuebel, Julia; Chen, Kaihua; Gaborski, Thomas R; Engelhardt, Britta; McGrath, James L (2024). Use of the MicroSiM (µSiM) Barrier Tissue Platform for Modeling the Blood-Brain Barrier. Journal of visualized experiments(203) MYJoVE Corporation 10.3791/65258

2023

Ruef, Nora; Martínez Magdaleno, Jose; Ficht, Xenia; Purvanov, Vladimir; Palayret, Matthieu; Wissmann, Stefanie; Pfenninger, Petra; Stolp, Bettina; Thelen, Flavian; Barreto de Albuquerque, Juliana; Germann, Philipp; Sharpe, James; Abe, Jun; Legler, Daniel F; Stein, Jens V (2023). Exocrine gland-resident memory CD8+ T cells use mechanosensing for tissue surveillance. Science immunology, 8(90), eadd5724. American Association for the Advancement of Science 10.1126/sciimmunol.add5724

Johann, Lisa; Soldati, Sasha; Müller, Kristin; Lampe, Josephine; Marini, Federico; Klein, Matthias; Schramm, Eva; Ries, Nathalie; Schelmbauer, Carsten; Palagi, Ilaria; Karram, Khalad; Assmann, Julian C; Khan, Mahtab A; Wenzel, Jan; Schmidt, Mirko Hh; Körbelin, Jakob; Schlüter, Dirk; van Loo, Geert; Bopp, Tobias; Engelhardt, Britta; ... (2023). A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS. The journal of clinical investigation, 133(24) American Society for Clinical Investigation 10.1172/JCI168314

Pietilä, Riikka; Del Gaudio, Francesca; He, Liqun; Vázquez-Liébanas, Elisa; Vanlandewijck, Michael; Muhl, Lars; Mocci, Giuseppe; Bjørnholm, Katrine D; Lindblad, Caroline; Fletcher-Sandersjöö, Alexander; Svensson, Mikael; Thelin, Eric P; Liu, Jianping; van Voorden, A Jantine; Torres, Monica; Antila, Salli; Xin, Li; Karlström, Helena; Storm-Mathisen, Jon; Bergersen, Linda Hildegard; ... (2023). Molecular anatomy of adult mouse leptomeninges. Neuron, 111(23), 3745-3764.e7. Elsevier 10.1016/j.neuron.2023.09.002

Stüdle, Chiara; Nishihara, Hideaki; Wischnewski, Sven; Kulsvehagen, Laila; Perriot, Sylvain; Ishikawa, Hiroshi; Schroten, Horst; Frank, Stephan; Deigendesch, Nikolaus; Du Pasquier, Renaud; Schirmer, Lucas; Pröbstel, Anne-Katrin; Engelhardt, Britta (2023). SARS-CoV-2 infects epithelial cells of the blood-cerebrospinal fluid barrier rather than endothelial cells or pericytes of the blood-brain barrier. Fluids and barriers of the CNS, 20(1), p. 76. BioMed Central 10.1186/s12987-023-00479-4

Garcia-Seyda, Nicolas; Song, Solene; Seveau de Noray, Valentine; David-Broglio, Luc; Matti, Christoph; Artinger, Marc; Dupuy, Florian; Biarnes-Pelicot, Martine; Valignat, Marie-Pierre; Legler, Daniel F; Bajénoff, Marc; Theodoly, Olivier (2023). Naive T lymphocytes chemotax long distance to CCL21 but not to a source of bioactive S1P. iScience, 26(10), p. 107695. Elsevier 10.1016/j.isci.2023.107695

Saltarin, Federico; Wegmüller, Adrian; Bejarano, Leire; Ildiz, Eco Su; Zwicky, Pascale; Vianin, Andréj; Spadin, Florentin; Soukup, Klara; Wischnewski, Vladimir; Engelhardt, Britta; Deutsch, Urban; Marques, Ines J.; Frenz, Martin; Joyce, Johanna A.; Lyck, Ruth (2023). Compromised Blood-Brain Barrier Junctions Enhance Melanoma Cell Intercalation and Extravasation. Cancers, 15(20), p. 5071. MDPI AG 10.3390/cancers15205071

Liu, Huan; Ishikawa-Ankerhold, Hellen; Winterhalter, Julia; Lorenz, Michael; Vladymyrov, Mykhailo; Massberg, Steffen; Schulz, Christian; Orban, Mathias (2023). Multiphoton In Vivo Microscopy of Embryonic Thrombopoiesis Reveals the Generation of Platelets through Budding. Cells, 12(19) MDPI 10.3390/cells12192411

Mapunda, Josephine A; Pareja, Javier; Vladymyrov, Mykhailo; Bouillet, Elisa; Hélie, Pauline; Pleskač, Petr; Barcos, Sara; Andrae, Johanna; Vestweber, Dietmar; McDonald, Donald M; Betsholtz, Christer; Deutsch, Urban; Proulx, Steven T; Engelhardt, Britta (2023). VE-cadherin in arachnoid and pia mater cells serves as a suitable landmark for in vivo imaging of CNS immune surveillance and inflammation. Nature communications, 14(1), p. 5837. Nature Publishing Group 10.1038/s41467-023-41580-4

Lazarevic, Ivana; Soldati, Sasha; Mapunda, Josephine A; Rudolph, Henriette; Rosito, Maria; de Oliveira, Alex Cardoso; Enzmann, Gaby; Nishihara, Hideaki; Ishikawa, Hiroshi; Tenenbaum, Tobias; Schroten, Horst; Engelhardt, Britta (2023). Correction to: The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis. Fluids and barriers of the CNS, 20(1), p. 55. BioMed Central 10.1186/s12987-023-00457-w

Gonzalez-Fierro, Carmen; Fonte, Coralie; Dufourd, Eloïse; Cazaentre, Vincent; Aydin, Sidar; Engelhardt, Britta; Caspi, Rachel R; Xu, Biying; Martin-Blondel, Guillaume; Spicer, Julie A; Trapani, Joseph A; Bauer, Jan; Liblau, Roland S; Bost, Chloé (2023). Effects of a Small-Molecule Perforin Inhibitor in a Mouse Model of CD8 T Cell-Mediated Neuroinflammation. Neurology: Neuroimmunology and Neuroinflammation, 10(4) Wolters Kluwer Health 10.1212/NXI.0000000000200117

Lazarevic, Ivana; Soldati, Sasha; Mapunda, Josephine A; Rudolph, Henriette; Rosito, Maria; Cardoso de Oliveira, Alex; Enzmann, Gaby; Nishihara, Hideaki; Ishikawa, Hiroshi; Tenenbaum, Tobias; Schroten, Horst; Engelhardt, Britta (2023). The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis. Fluids and barriers of the CNS, 20(1), p. 39. BioMed Central 10.1186/s12987-023-00441-4

Aydin, Sidar; Pareja, Javier; Schallenberg, Vivianne M; Klopstein, Armelle; Gruber, Thomas; Page, Nicolas; Bouillet, Elisa; Blanchard, Nicolas; Liblau, Roland; Körbelin, Jakob; Schwaninger, Markus; Johnson, Aaron J; Schenk, Mirjam; Deutsch, Urban; Merkler, Doron; Engelhardt, Britta (2023). Antigen recognition detains CD8+ T cells at the blood-brain barrier and contributes to its breakdown. Nature communications, 14(1), p. 3106. Nature Publishing Group 10.1038/s41467-023-38703-2

Soldati, Sasha; Bär, Alexander; Vladymyrov, Mykhailo; Glavin, Dale; McGrath, James L; Gosselet, Fabien; Nishihara, Hideaki; Goelz, Susan; Engelhardt, Britta (2023). High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4+ T cell arrest on the inflamed BBB under flow in vitro. Journal of neuroinflammation, 20(1), p. 123. BioMed Central 10.1186/s12974-023-02797-8

Matsuo, Kinya; Engelhardt, Britta; Nishihara, Hideaki (2023). Differentiation of Human Induced Pluripotent Stem Cells to Brain Microvascular Endothelial Cell-Like Cells with a Mature Immune Phenotype. Journal of visualized experiments(195) MYJoVE Corporation 10.3791/65134

Spera, Irene; Cousin, Nikola; Ries, Miriam; Kedracka, Anna; Castillo, Alina; Aleandri, Simone; Vladymyrov, Mykhailo; Mapunda, Josephine A; Engelhardt, Britta; Luciani, Paola; Detmar, Michael; Proulx, Steven T (2023). Open pathways for cerebrospinal fluid outflow at the cribriform plate along the olfactory nerves. EBioMedicine, 91(104558), p. 104558. Elsevier 10.1016/j.ebiom.2023.104558

Li, Zhilin; Antila, Salli; Nurmi, Harri; Chilov, Dmitri; Korhonen, Emilia A; Fang, Shentong; Karaman, Sinem; Engelhardt, Britta; Alitalo, Kari (2023). Blockade of VEGFR3 signaling leads to functional impairment of dural lymphatic vessels without affecting autoimmune neuroinflammation. Science immunology, 8(82), eabq0375. American Association for the Advancement of Science 10.1126/sciimmunol.abq0375

Wishart, Claire L; Spiteri, Alanna G; Locatelli, Giuseppe; King, Nicholas J C (2023). Integrating transcriptomic datasets across neurological disease identifies unique myeloid subpopulations driving disease-specific signatures. GLIA, 71(4), pp. 904-925. Wiley-Blackwell 10.1002/glia.24314

C Ivan, Daniela; Berve, Kristina Carolin; Walthert, Sabrina; Monaco, Gianni; Borst, Katharina; Bouillet, Elisa; Ferreira, Filipa; Lee, Henry; Steudler, Jasmin; Buch, Thorsten; Prinz, Marco; Engelhardt, Britta; Locatelli, Giuseppe (2023). Insulin-like growth factor-1 receptor controls the function of CNS-resident macrophages and their contribution to neuroinflammation. Acta neuropathologica communications, 11(1), p. 35. 10.1186/s40478-023-01535-8

Locatelli, Giuseppe; Marques-Ferreira, Filipa; Katsoulas, Antonis; Kalaitzaki, Vasileia; Krueger, Martin; Ingold-Heppner, Barbara; Walthert, Sabrina; Sankowski, Roman; Prazeres da Costa, Olivia; Dolga, Amalia; Huber, Magdalena; Gold, Maike; Culmsee, Carsten; Waisman, Ari; Bechmann, Ingo; Milchevskaya, Vladislava; Prinz, Marco; Tresch, Achim; Becher, Burkhard and Buch, Thorsten (2023). IGF1R expression by adult oligodendrocytes is not required in the steady-state but supports neuroinflammation. GLIA, 71(3), pp. 616-632. Wiley-Blackwell 10.1002/glia.24299

Proulx, Steven T; Engelhardt, Britta (2023). Macrophages clear the way for CNS fluid flow. The lancet. Neurology, 22(3), pp. 194-195. Elsevier 10.1016/S1474-4422(23)00028-5

Artinger, Marc; Gerken, Oliver J; Legler, Daniel F (2023). Heparin Specifically Interacts with Basic BBXB Motifs of the Chemokine CCL21 to Define CCR7 Signaling. International journal of molecular sciences, 24(2) MDPI 10.3390/ijms24021670

Proulx, Steven T (2023). The peri-olfactory pathway: An "e-scent-ial" route for cerebrospinal fluid clearance? EBioMedicine, 87(104417), p. 104417. Elsevier 10.1016/j.ebiom.2022.104417

Sigmund, Elena C; Bauer, Aline; Jakobs, Barbara D; Tatliadim, Hazal; Tacconi, Carlotta; Thelen, Marcus; Legler, Daniel F; Halin, Cornelia (2023). Reassessing the adrenomedullin scavenging function of ACKR3 in lymphatic endothelial cells. PLoS ONE, 18(5), e0285597. Public Library of Science 10.1371/journal.pone.0285597

van Os, Lisette; Engelhardt, Britta; Guenat, Olivier T. (2023). Integration of immune cells in organs-on-chips: a tutorial. Frontiers in Bioengineering and Biotechnology, 11, p. 1191104. Frontiers Media 10.3389/fbioe.2023.1191104

Melgrati, Serena; Gerken, Oliver J; Artinger, Marc; Radice, Egle; Szpakowska, Martyna; Chevigné, Andy; D'Uonnolo, Giulia; Antonello, Paola; Thelen, Sylvia; Pelczar, Pawel; Legler, Daniel F; Thelen, Marcus (2023). GPR182 is a broadly scavenging atypical chemokine receptor influencing T-independent immunity. Frontiers in immunology, 14(1242531), p. 1242531. Frontiers Research Foundation 10.3389/fimmu.2023.1242531

2022

Nishihara, Hideaki; Perriot, Sylvain; Gastfriend, Benjamin D; Steinfort, Marel; Cibien, Celine; Soldati, Sasha; Matsuo, Kinya; Guimbal, Sarah; Mathias, Amandine; Palecek, Sean P; Shusta, Eric V; Du Pasquier, Renaud; Engelhardt, Britta (2022). Intrinsic blood-brain barrier dysfunction contributes to multiple sclerosis pathogenesis. Brain : a journal of neurology, 145(12), pp. 4334-4348. Oxford University Press 10.1093/brain/awac019

Bagatella, Stefano; Haghayegh Jahromi, Neda; Monney, Camille; Polidori, Margherita; Gall, Flavio Max; Marchionatti, Emma; Serra, Fabienne; Riedl, Rainer; Engelhardt, Britta; Oevermann, Anna (2022). Bovine neutrophil chemotaxis to Listeria monocytogenes in neurolisteriosis depends on microglia-released rather than bacterial factors. Journal of neuroinflammation, 19(1), p. 304. BioMed Central 10.1186/s12974-022-02653-1

Ineichen, Benjamin V; Okar, Serhat V; Proulx, Steven T; Engelhardt, Britta; Lassmann, Hans; Reich, Daniel S (2022). Perivascular spaces and their role in neuroinflammation. Neuron, 110(21), pp. 3566-3581. Cell Press 10.1016/j.neuron.2022.10.024

Steudler, Jasmin; Ecott, Timothy; Ivan, Daniela C; Bouillet, Elisa; Walthert, Sabrina; Berve, Kristina; Dick, Tobias P; Engelhardt, Britta; Locatelli, Giuseppe (2022). Autoimmune neuroinflammation triggers mitochondrial oxidation in oligodendrocytes. GLIA, 70(11), pp. 2045-2061. Wiley-Blackwell 10.1002/glia.24235

Carare, Roxana O; Engelhardt, Britta; Perry, Victor Hugh; Kalaria, Raj (2022). In memoriam, Roy Weller (1938-2022). Acta neuropathologica, 144(5), pp. 803-806. Springer-Verlag 10.1007/s00401-022-02502-8

Kemble, Alicia M; Hornsperger, Benoit; Ruf, Iris; Richter, Hans; Benz, Jörg; Kuhn, Bernd; Heer, Dominik; Wittwer, Matthias; Engelhardt, Britta; Grether, Uwe; Collin, Ludovic (2022). A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature. PLoS ONE, 17(9), e0268590. Public Library of Science 10.1371/journal.pone.0268590

Lorusso, Girieca; Wyss, Christof B; Kuonen, François; Vannini, Nicola; Billottet, Clotilde; Duffey, Nathalie; Pineau, Raphael; Lan, Qiang; Wirapati, Pratyaksha; Barras, David; Tancredi, Alessandro; Lyck, Ruth; Lehr, Hans-Anton; Engelhardt, Britta; Delorenzi, Mauro; Bikfalvi, Andreas; Rüegg, Curzio (2022). Connexins orchestrate progression of breast cancer metastasis to the brain by promoting FAK activation. Science translational medicine, 14(661), eaax8933. American Association for the Advancement of Science 10.1126/scitranslmed.aax8933

McCloskey, Molly C; Kasap, Pelin; Ahmad, S Danial; Su, Shiuan-Haur; Chen, Kaihua; Mansouri, Mehran; Ramesh, Natalie; Nishihara, Hideaki; Belyaev, Yury; Abhyankar, Vinay V; Begolo, Stefano; Singer, Benjamin H; Webb, Kevin F; Kurabayashi, Katsuo; Flax, Jonathan; Waugh, Richard E; Engelhardt, Britta; McGrath, James L (2022). The Modular μSiM: a Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro. Advanced healthcare materials, 11(18), e2200804. Wiley 10.1002/adhm.202200804

Rossatti, Pascal; Redpath, Gregory M I; Ziegler, Luca; Samson, Guerric P B; Clamagirand, Camille D; Legler, Daniel F; Rossy, Jérémie (2022). Rapid increase in transferrin receptor recycling promotes adhesion during T cell activation. BMC biology, 20(1), p. 189. BioMed Central 10.1186/s12915-022-01386-0

Proulx, Steven T.; Engelhardt, Britta (2022). Central nervous system zoning: How brain barriers establish subdivisions for CNS immune privilege and immune surveillance. Journal of internal medicine, 292(1), pp. 47-67. Wiley 10.1111/joim.13469

Guse, Kirsten; Hagemann, Nina; Thiele, Lisa; Remlinger, Jana; Salmen, Anke; Hoepner, Robert; Keller, Irene; Meyer, Patricia; Grandgirard, Denis; Leib, Stephen; Vassella, Erik; Locatelli, Giuseppe; Hermann, Dirk M; Chan, Andrew Hao-Kuang (2022). CNS Antigen-Specific Neuroinflammation Attenuates Ischemic Stroke With Involvement of Polarized Myeloid Cells. Neurology: neuroimmunology & neuroinflammation, 9(4) Wolters Kluwer Health 10.1212/NXI.0000000000001168

Cousins, Oliver; Hodges, Angela; Schubert, Julia; Veronese, Mattia; Turkheimer, Federico; Miyan, Jaleel; Engelhardt, Britta; Roncaroli, Federico (2022). The Blood-CSF-Brain Route of Neurological Disease: The Indirect Pathway into the Brain. Neuropathology and applied neurobiology, 48(4), e12789. Wiley 10.1111/nan.12789

Engelhardt, Britta; Comabella, Manuel; Chan, Andrew (2022). Multiple Sclerosis: Immunopathological heterogeneity and its implications. European journal of immunology, 52(6), pp. 869-881. Wiley-VCH 10.1002/eji.202149757

Artinger, Marc; Gerken, Oliver J; Purvanov, Vladimir; Legler, Daniel F (2022). Distinct Fates of Chemokine and Surrogate Molecule Gradients: Consequences for CCR7-Guided Dendritic Cell Migration. Frontiers in immunology, 13, p. 913366. Frontiers Research Foundation 10.3389/fimmu.2022.913366

Patel, Monica; Matti, Christoph; Grimsey, Natasha L; Legler, Daniel F; Javitch, Jonathan A; Finlay, David B; Glass, Michelle (2022). Delineating the interactions between the cannabinoid CB2 receptor and its regulatory effectors; β-arrestins and GPCR kinases. British journal of pharmacology, 179(10), pp. 2223-2239. Wiley 10.1111/bph.15748

Gerken, Oliver J; Artinger, Marc; Legler, Daniel F (2022). Shifting CCR7 towards Its Monomeric Form Augments CCL19 Binding and Uptake. Cells, 11(9) MDPI 10.3390/cells11091444

Dzung, Andreas; Saltari, Annalisa; Tiso, Natascia; Lyck, Ruth; Dummer, Reinhard; Levesque, Mitchell P (2022). STK11 Prevents Invasion Through STAT3/5 and FAK Repression in Cutaneous Melanoma. Journal of investigative dermatology, 142(4), 1171-1182.e10. Elsevier 10.1016/j.jid.2021.09.035

Holder, Brianna M; Tolan, Shaina E; Heinrich, Kaleb K; Miller, Kaitlin C; Hudson, Natalie; Nehra, Geetika; Pizzo, Michelle E; Storck, Steffen E; Elmquist, William F; Engelhardt, Britta; Loryan, Irena; Toborek, Michal; Bauer, Bjoern; Hartz, Anika M S; Kim, Brandon J (2022). Brain barriers virtual: an interim solution or future opportunity? Fluids and barriers of the CNS, 19(1), p. 19. BioMed Central 10.1186/s12987-022-00314-2

Mapunda, Josephine A; Tibar, Houyam; Regragui, Wafa; Engelhardt, Britta (2022). How Does the Immune System Enter the Brain? Frontiers in immunology, 13(805657), p. 805657. Frontiers Research Foundation 10.3389/fimmu.2022.805657

Martinez-Salazar, Maria; Holwerda, Melle; Stüdle, Chiara; Piragyte, Indre; Mercader, Nadia; Engelhardt, Britta; Rieben, Robert; Döring, Yvonne (2022). COVID-19 and the Vasculature: Current Aspects and Long-Term Consequences. Frontiers in cell and developmental biology, 10, p. 824851. Frontiers 10.3389/fcell.2022.824851

Decker, Yann; Krämer, Jonas; Xin, Li; Müller, Andreas; Scheller, Anja; Fassbender, Klaus; Proulx, Steven T. (2022). Magnetic resonance imaging of cerebrospinal fluid outflow after low-rate lateral ventricle infusion in mice. JCI insight, 7(3) JCI Insight 10.1172/jci.insight.150881

Friess, Mona C; Kritikos, Ioannis; Schineis, Philipp; Medina-Sanchez, Jessica Danielly; Gkountidi, Anastasia-Olga; Vallone, Angela; Sigmund, Elena C; Schwitter, Corina; Vranova, Martina; Matti, Christoph; Arasa, Jorge; Saygili Demir, Cansaran; Bovay, Esther; Proulx, Steven T; Tomura, Michio; Rot, Antal; Legler, Daniel F; Petrova, Tatiana V; Halin, Cornelia (2022). Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics. Cell reports, 38(5), p. 110334. Cell Press 10.1016/j.celrep.2022.110334

Spiteri, Alanna G; Wishart, Claire L; Pamphlett, Roger; Locatelli, Giuseppe; King, Nicholas J C (2022). Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function. Acta neuropathologica, 143(2), pp. 179-224. Springer-Verlag 10.1007/s00401-021-02384-2

Marchetti, Luca; Francisco, David; Soldati, Sasha; Haghayegh Jahromi, Neda; Barcos, Sara; Gruber, Isabelle; Pareja R., Javier; Thiriot, Aude; von Andrian, Ulrich; Deutsch, Urban; Lyck, Ruth; Bruggmann, Rémy; Engelhardt, Britta (2022). ACKR1 favors transcellular over paracellular T-cell diapedesis across the blood-brain barrier in neuroinflammation in vitro. European journal of immunology, 52(1), pp. 161-177. Wiley 10.1002/eji.202149238

Nishihara, Hideaki; Engelhardt, Britta (2022). Brain Barriers and Multiple Sclerosis: Novel Treatment Approaches from a Brain Barriers Perspective. Handbook of experimental pharmacology, 273, pp. 295-329. Springer 10.1007/164_2020_407

Galoppin, Manon; Kari, Saniya; Soldati, Sasha; Pal, Arindam; Rival, Manon; Engelhardt, Britta; Astier, Anne; Thouvenot, Eric (2022). Full spectrum of vitamin D immunomodulation in multiple sclerosis: mechanisms and therapeutic implications. Brain Communications, 4(4), fcac171. Oxford University Press 10.1093/braincomms/fcac171

Lyck, Ruth; Nishihara, Hideaki; Aydin, Sidar; Soldati, Sasha; Engelhardt, Britta (2022). Modeling Brain Vasculature Immune Interactions In Vitro. Cold Spring Harbor perspectives in medicine, 13(9), a041185. Cold Spring Harbor Laboratory Press 10.1101/cshperspect.a041185

2021

Seumen, Clovis H T; Tomasiunaite, Urte; Legler, Daniel F; Hauck, Christof R (2021). Elimination of negative feedback in TLR signalling allows rapid and hypersensitive detection of microbial contaminants. Scientific reports, 11(1), p. 24414. Springer Nature 10.1038/s41598-021-03618-9

Gastfriend, Benjamin D; Nishihara, Hideaki; Canfield, Scott G; Foreman, Koji L; Engelhardt, Britta; Palecek, Sean P; Shusta, Eric V (2021). Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells. eLife, 10 eLife Sciences Publications 10.7554/eLife.70992

Uetz-von Allmen, Edith; Samson, Guerric P. B.; Purvanov, Vladimir; Maeda, Takahiro; Legler, Daniel F. (2021). CAL-1 as Cellular Model System to Study CCR7-Guided Human Dendritic Cell Migration. Frontiers in immunology, 12, p. 702453. Frontiers Research Foundation 10.3389/fimmu.2021.702453

Thomsen, Tanja; Reissmann, Regina; Kaba, Elisa; Engelhardt, Britta; Klok, Harm-Anton (2021). Covalent and Noncovalent Conjugation of Degradable Polymer Nanoparticles to T Lymphocytes. Biomacromolecules, 22(8), pp. 3416-3430. American Chemical Society 10.1021/acs.biomac.1c00488

Engelhardt, Britta (2021). Private immune protection at the border of the central nervous system. Nature, 596(7870), pp. 38-40. Springer Nature 10.1038/d41586-021-01962-4

Nishihara, Hideaki; Gastfriend, Benjamin D; Kasap, Pelin; Palecek, Sean P; Shusta, Eric V; Engelhardt, Britta (2021). Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions. STAR protocols, 2(2), p. 100563. Elsevier 10.1016/j.xpro.2021.100563

Derada Troletti, Claudio; Enzmann, Gaby; Chiurchiù, Valerio; Kamermans, Alwin; Tietz, Silvia Martina; Norris, Paul C; Haghayegh Jahromi, Neda; Leuti, Alessandro; van der Pol, Susanne M A; Schouten, Marijn; Serhan, Charles N; de Vries, Helga E; Engelhardt, Britta; Kooij, Gijs (2021). Pro-resolving lipid mediator lipoxin A4 attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome. Cell reports, 35(9), p. 109201. Cell Press 10.1016/j.celrep.2021.109201

Hamminger, Patricia; Marchetti, Luca; Preglej, Teresa; Platzer, René; Zhu, Ci; Kamnev, Anton; Rica, Ramona; Stolz, Valentina; Sandner, Lisa; Alteneder, Marlis; Kaba, Elisa; Waltenberger, Darina; Huppa, Johannes B; Trauner, Michael; Bock, Christoph; Lyck, Ruth; Bauer, Jan; Dupré, Loïc; Seiser, Christian; Boucheron, Nicole; ... (2021). Histone deacetylase 1 controls CD4+ T cell trafficking in autoinflammatory diseases. Journal of autoimmunity, 119, p. 102610. Elsevier 10.1016/j.jaut.2021.102610

Baier, Felix Alexander; Sánchez-Taltavull, Daniel; Yarahmadov, Tural; Castellà, Cristina Gómez; Jebbawi, Fadi; Keogh, Adrian; Tombolini, Riccardo; Odriozola, Adolfo; Castro Dias, Mariana; Deutsch, Urban; Furuse, Mikio; Engelhardt, Britta; Zuber, Benoît; Odermatt, Alex; Candinas, Daniel; Keogh-Stroka, Deborah M. (2021). Loss of claudin-3 impairs hepatic metabolism, biliary barrier function and cell proliferation in the murine liver. Cellular and molecular gastroenterology and hepatology, 12(2), pp. 745-767. Elsevier 10.1016/j.jcmgh.2021.04.003

Reynoso-Moreno, Ines; Tietz, Silvia; Vallini, Erika; Engelhardt, Britta; Gertsch, Jürg; Chicca, Andrea (2021). Selective Endocannabinoid Reuptake Inhibitor WOBE437 Reduces Disease Progression in a Mouse Model of Multiple Sclerosis. ACS pharmacology & translational science, 4(2), pp. 765-779. ACS Publications 10.1021/acsptsci.0c00214

Ayer, Maxime; Burri, Olivier; Guiet, Romain; Seitz, Arne; Kaba, Elisa; Engelhardt, Britta; Klok, Harm-Anton (2021). Biotin-NeutrAvidin Mediated Immobilization of Polymer Micro- and Nanoparticles on T Lymphocytes. Bioconjugate chemistry, 32(3), pp. 541-552. American Chemical Society 10.1021/acs.bioconjchem.1c00026

Imeri, Faik; Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Schwalm, Stephanie; Pfeilschifter, Josef; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2021). Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis. Neuropharmacology, 186, p. 108464. Elsevier 10.1016/j.neuropharm.2021.108464

Loy, Kristina; Fourneau, Julie; Meng, Ning; Denecke, Carmen; Locatelli, Giuseppe; Bareyre, Florence M (2021). Semaphorin 7A restricts serotonergic innervation and ensures recovery after spinal cord injury. Cellular and molecular life sciences : CMLS, 78(6), pp. 2911-2927. Springer 10.1007/s00018-020-03682-w

Polomska, Anna K; Proulx, Steven T. (2021). Imaging technology of the lymphatic system. Advanced drug delivery reviews, 170, pp. 294-311. Elsevier 10.1016/j.addr.2020.08.013

Ivan, Daniela C.; Walthert, Sabrina; Berve, Kristina; Steudler, Jasmin; Locatelli, Giuseppe (2021). Dwellers and Trespassers: Mononuclear Phagocytes at the Borders of the Central Nervous System. Frontiers in immunology, 11, p. 609921. Frontiers Research Foundation 10.3389/fimmu.2020.609921

Weber, Florian; C. Ivan, Daniela; Proulx, Steven T.; Locatelli, Giuseppe; Aleandri, Simone; Luciani, Paola (2021). Beyond Trial and Error: A Systematic Development of Liposomes Targeting Primary Macrophages. Advanced nanoBiomed research, 1(3), p. 2000098. Wiley 10.1002/anbr.202000098

Proulx, Steven T. (2021). Cerebrospinal fluid outflow: a review of the historical and contemporary evidence for arachnoid villi, perineural routes, and dural lymphatics. Cellular and molecular life sciences : CMLS, 78(6), pp. 2429-2457. Springer 10.1007/s00018-020-03706-5

Hélie, Pauline; Camacho-Toledano, Celia; Lesec, Léonie; Seillier, Célia; Miralles, Antonio J; Ortega, Maria Cristina; Guérit, Sylvaine; Lebas, Héloïse; Bardou, Isabelle; Vila-Del Sol, Virginia; Vivien, Denis; Le Mauff, Brigitte; Clemente, Diego; Docagne, Fabian; Toutirais, Olivier (2021). Tissue plasminogen activator worsens experimental autoimmune encephalomyelitis by complementary actions on lymphoid and myeloid cell responses. Journal of neuroinflammation, 18(1), p. 52. BioMed Central 10.1186/s12974-021-02102-5

Ayer, Maxime; Schuster, Markus; Gruber, Isabelle; Blatti, Claudia; Kaba, Elisa; Enzmann, Gaby; Burri, Olivier; Guiet, Romain; Seitz, Arne; Engelhardt, Britta; Klok, Harm-Anton (2021). T Cell-Mediated Transport of Polymer Nanoparticles across the Blood-Brain Barrier. Advanced healthcare materials, 10(2), e2001375. Wiley 10.1002/adhm.202001375

Ivan, Daniela C.; Walthert, Sabrina; Locatelli, Giuseppe (2021). Central Nervous System Barriers Impact Distribution and Expression of iNOS and Arginase-1 in Infiltrating Macrophages During Neuroinflammation. Frontiers in immunology, 12 Frontiers Research Foundation 10.3389/fimmu.2021.666961

Castro Dias, Mariana; Odriozola Quesada, Adolfo; Soldati, Sasha; Bösch, Fabio; Gruber, Isabelle; Hildbrand, Tobias; Sönmez, Derya; Khire, Tejas; Witz, Guillaume; McGrath, James L.; Piontek, Jörg; Kondoh, Masuo; Deutsch, Urban; Zuber, Benoît; Engelhardt, Britta (2021). Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood–brain barrier. Journal of cell science, 134(8) Company of Biologists Limited 10.1242/jcs.253880

Vizcaino, Josue Page; Saltarin, Federico; Belyaev, Yury; Lyck, Ruth; Lasser, Tobias; Favaro, Paolo (2021). Learning to Reconstruct Confocal Microscopy Stacks From Single Light Field Images. IEEE transactions on computational imaging, 7, pp. 775-788. IEEE 10.1109/TCI.2021.3097611

Sasson, Esther; Anzi, Shira; Bell, Batia; Yakovian, Oren; Zorsky, Meshi; Deutsch, Urban; Engelhardt, Britta; Sherman, Eilon; Vatine, Gad; Dzikowski, Ron; Ben-Zvi, Ayal (2021). Nano-scale architecture of blood-brain barrier tight-junctions. eLife, 10 eLife Sciences Publications 10.7554/eLife.63253

2020

Nishihara, Hideaki; Gastfriend, Benjamin D; Soldati, Sasha; Perriot, Sylvain; Mathias, Amandine; Sano, Yasuteru; Shimizu, Fumitaka; Gosselet, Fabien; Kanda, Takashi; Palecek, Sean P; Du Pasquier, Renaud; Shusta, Eric V; Engelhardt, Britta (2020). Advancing human induced pluripotent stem cell-derived blood-brain barrier models for studying immune cell interactions. FASEB journal, 34(12), pp. 16693-16715. Federation of American Societies for Experimental Biology 10.1096/fj.202001507RR

Locatelli, Giuseppe; Engelhardt, Britta (2020). Microglia Get a Little Help from "Th"-eir Friends. Immunity, 53(3), pp. 484-486. Cell Press 10.1016/j.immuni.2020.08.011

Stepanovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Tietz, Silvia; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2020). Morpholino Analogues of Fingolimod as Novel and Selective S1P1 Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis. International journal of molecular sciences, 21(18), pp. 1-17. MDPI 10.3390/ijms21186463

Francisco, David M F; Marchetti, Luca; Rodríguez-Lorenzo, Sabela; Frías-Anaya, Eduardo; Figueiredo, Ricardo M; Winter, Peter; Romero, Ignacio Andres; de Vries, Helga E; Engelhardt, Britta; Bruggmann, Rémy (2020). Advancing brain barriers RNA sequencing: guidelines from experimental design to publication. Fluids and barriers of the CNS, 17(1), p. 51. BioMed Central 10.1186/s12987-020-00207-2

Dieterich, Lothar C; Tacconi, Carlotta; Menzi, Franziska; Proulx, Steven T; Kapaklikaya, Kübra; Hamada, Michito; Takahashi, Satoru; Detmar, Michael (2020). Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis. Angiogenesis, 23(3), pp. 411-423. Springer Netherlands 10.1007/s10456-020-09721-1

Heymans, Marjolein; Figueiredo, Ricardo; Dehouck, Lucie; Francisco, David; Sano, Yasuteru; Shimizu, Fumitaka; Kanda, Takashi; Bruggmann, Rémy; Engelhardt, Britta; Winter, Peter; Gosselet, Fabien; Culot, Maxime (2020). Contribution of brain pericytes in blood-brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells. Fluids and barriers of the CNS, 17(1), p. 48. BioMed Central 10.1186/s12987-020-00208-1

Cosgrove, Jason; Novkovic, Mario; Albrecht, Stefan; Pikor, Natalia B; Zhou, Zhaoukun; Onder, Lucas; Mörbe, Urs; Cupovic, Jovana; Miller, Helen; Alden, Kieran; Thuery, Anne; O'Toole, Peter; Pinter, Rita; Jarrett, Simon; Taylor, Emily; Venetz, Daniel; Heller, Manfred; Uguccioni, Mariagrazia; Legler, Daniel F; Lacey, Charles J; ... (2020). B cell zone reticular cell microenvironments shape CXCL13 gradient formation. Nature Communications, 11(1), p. 3677. Springer Nature 10.1038/s41467-020-17135-2

Bruggisser, Julia; Tarek, Basma; Wyder, Marianne; Müller, Philipp; von Ballmoos, Christoph; Witz, Guillaume; Enzmann, Gaby; Deutsch, Urban; Engelhardt, Britta; Posthaus, Horst (2020). CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin. Cell host & microbe, 28(1), pp. 69-78. Cell Press 10.1016/j.chom.2020.05.003

Hahn, Julia; Günter, Manina; Schuhmacher, Juliane; Bieber, Kristin; Pöschel, Simone; Schütz, Monika; Engelhardt, Britta; Oster, Henrik; Sina, Christian; Lange, Tanja; Autenrieth, Stella E (2020). Sleep enhances numbers and function of monocytes and improves bacterial infection outcome in mice. Brain, behavior, and immunity, 87, pp. 329-338. Elsevier 10.1016/j.bbi.2020.01.001

Prange, L.; Villiger, A.; Schaer, S.; Dach, R.; Sidorov, D.; Beutler, G.; Jäggi, A. (4 May 2020). CODE IGS reference products including Galileo (Unpublished). In: EGU General Assembly 2020, Sharing Geosciences Online. Vienna, Austria. 04-08 May 2020.

Bachmann, Samia B; Proulx, Steven T.; He, Yuliang; Ries, Miriam; Detmar, Michael (2020). Differential effects of anaesthesia on the contractility of lymphatic vessels in vivo: authors' reply. The journal of physiology, 598(10), p. 2037. The Physiological Society 10.1113/JP279712

Li, Zhilin; Korhonen, Emilia A; Merlini, Arianna; Strauss, Judith; Wihuri, Eleonoora; Nurmi, Harri; Antila, Salli; Paech, Jennifer; Deutsch, Urban; Engelhardt, Britta; Chintharlapalli, Sudhakar; Koh, Gou Young; Flügel, Alexander; Alitalo, Kari (2020). Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS. The journal of clinical investigation, 130(4), pp. 1977-1990. American Society for Clinical Investigation 10.1172/JCI130308

Marchetti, Luca; Engelhardt, Britta (2020). Immune cell trafficking across the blood-brain barrier in the absence and presence of neuroinflammation. Vascular biology (Bristol, England), 2(1), H1-H18. 10.1530/VB-19-0033

Nishihara, Hideaki; Soldati, Sasha; Mossu, Adrien; Rosito, Maria; Rudolph, Henriette; Muller, William A; Latorre, Daniela; Sallusto, Federica; Sospedra, Mireia; Martin, Roland; Ishikawa, Hiroshi; Tenenbaum, Tobias; Schroten, Horst; Gosselet, Fabien; Engelhardt, Britta (2020). Human CD4+ T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro. Fluids and barriers of the CNS, 17(1), p. 3. BioMed Central 10.1186/s12987-019-0165-2

Haghayegh Jahromi, Neda; Marchetti, Luca; Moalli, Federica; Duc, Donovan; Basso, Camilla; Tardent, Heidi; Kaba, Elisa; Deutsch, Urban; Pot, Caroline; Sallusto, Federica; Stein, Jens V.; Engelhardt, Britta (2020). Intercellular Adhesion Molecule-1 (ICAM-1) and ICAM-2 Differentially Contribute to Peripheral Activation and CNS Entry of Autoaggressive Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis. Frontiers in immunology, 10(3056), p. 3056. Frontiers Research Foundation 10.3389/fimmu.2019.03056

Thiele née Schrewe, Lisa; Guse, Kirsten; Tietz, Silvia; Remlinger, Jana; Demir, Seray; Pedreiturria, Xiomara; Hoepner, Robert; Salmen, Anke; Pistor, Maximilian; Turner, Timothy; Engelhardt, Britta; Hermann, Dirk M; Lühder, Fred; Wiese, Stefan; Chan, Andrew (2020). Functional relevance of the multi-drug transporter abcg2 on teriflunomide therapy in an animal model of multiple sclerosis. Journal of neuroinflammation, 17(1), p. 9. BioMed Central 10.1186/s12974-019-1677-z

Kamm, Christian Philipp; Barin, L; Gobbi, C; Pot, C.; Calabrese, P; Salmen, Anke; Achtnichts, L; Kesselring, J; Puhan, M A; von Wyl, V. (2020). Factors influencing patient satisfaction with the first diagnostic consultation in multiple sclerosis: a Swiss Multiple Sclerosis Registry (SMSR) study. Journal of neurology, 267(1), pp. 153-161. Springer-Medizin-Verlag 10.1007/s00415-019-09563-y

De Niz, Mariana; Kehrer, Jessica; Brancucci, Nicolas M B; Moalli, Federica; Reynaud, Emmanuel G; Stein, Jens V; Frischknecht, Friedrich (2020). 3D imaging of undissected optically cleared Anopheles stephensi mosquitoes and midguts infected with Plasmodium parasites. PLoS ONE, 15(9), e0238134. Public Library of Science 10.1371/journal.pone.0238134

Hlushchuk, Ruslan; Haberthür, David; Soukup, Petr; Barré, Sebastien F.; Khoma, Oleksiy-Zakhar; Schittny, Johannes; Haghayegh Jahromi, Neda; Bouchet, Audrey; Engelhardt, Britta; Djonov, Valentin Georgiev (2020). Innovative high-resolution microCT imaging of animal brain vasculature. Brain structure & function, 225(9), pp. 2885-2895. Springer 10.1007/s00429-020-02158-8

Gericke, Christoph; Mallone, Anna; Engelhardt, Britta; Nitsch, Roger M; Ferretti, Maria Teresa (2020). Oligomeric Forms of Human Amyloid-Beta(1-42) Inhibit Antigen Presentation. Frontiers in immunology, 11, p. 1029. Frontiers Research Foundation 10.3389/fimmu.2020.01029

Van Laethem, François; Saba, Ingrid; Lu, Jinghua; Bhattacharya, Abhisek; Tai, Xuguang; Guinter, Terry I; Engelhardt, Britta; Alag, Amala; Rojano, Mirelle; Ashe, Jennifer M; Hanada, Ken-Ichi; Yang, James C; Sun, Peter D; Singer, Alfred (2020). Novel MHC-Independent αβTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus. Frontiers in immunology, 11, p. 1216. Frontiers Research Foundation 10.3389/fimmu.2020.01216

Vladymyrov, Mykhailo; Haghayegh Jahromi, Neda; Kaba, Elisa; Engelhardt, Britta; Ariga, Akitaka (2020). VivoFollow 2: Distortion-Free Multiphoton Intravital Imaging. Frontiers in physics, 7 Frontiers Media 10.3389/fphy.2019.00222

Engelhardt, Britta (2020). Maternal Infection Impairs Fetal Brain Development via Choroid Plexus Inflammation. Developmental cell, 55(5), pp. 519-521. Cell Press 10.1016/j.devcel.2020.11.011

2019

Dieterich, Lothar C; Kapaklikaya, Kübra; Cetintas, Timur; Proulx, Steven Thomas; Commerford, Catharina D; Ikenberg, Kristian; Bachmann, Samia B; Scholl, Jeannette; Detmar, Michael (2019). Transcriptional profiling of breast cancer-associated lymphatic vessels reveals VCAM-1 as regulator of lymphatic invasion and permeability. International journal of cancer, 145(10), pp. 2804-2815. Wiley-Blackwell 10.1002/ijc.32594

Ma, Qiaoli; Decker, Yann; Müller, Andreas; Ineichen, Benjamin V; Proulx, Steven T. (2019). Clearance of cerebrospinal fluid from the sacral spine through lymphatic vessels. Journal of experimental medicine, 216(11), pp. 2492-2502. Rockefeller University Press 10.1084/jem.20190351

Garnier, Arnaud; Laffont, Sophie; Garnier, Laure; Kaba, Elisa; Deutsch, Urban; Engelhardt, Britta; Guéry, Jean-Charles (2019). CD49d/CD29-integrin controls the accumulation of plasmacytoid dendritic cells into the CNS during neuroinflammation. European journal of immunology, 49(11), pp. 2030-2043. Wiley-VCH 10.1002/eji.201948086

Castro Dias, Mariana; Mapunda, Josephine A.; Vladymyrov, Mykhailo; Engelhardt, Britta (2019). Structure and Junctional Complexes of Endothelial, Epithelial and Glial Brain Barriers. International journal of molecular sciences, 20(21) Molecular Diversity Preservation International MDPI 10.3390/ijms20215372

Ma, Qiaoli; Schlegel, Felix; Bachmann, Samia B; Schneider, Hannah; Decker, Yann; Rudin, Markus; Weller, Michael; Proulx, Steven T.; Detmar, Michael (2019). Lymphatic outflow of cerebrospinal fluid is reduced in glioma. Scientific reports, 9(1), p. 14815. Springer Nature 10.1038/s41598-019-51373-9

Cossarizza, Andrea; Chang, Hyun-Dong; Radbruch, Andreas; Acs, Andreas; Adam, Dieter; Adam-Klages, Sabine; Agace, William W; Aghaeepour, Nima; Akdis, Mübeccel; Allez, Matthieu; Almeida, Larissa Nogueira; Alvisi, Giorgia; Anderson, Graham; Andrä, Immanuel; Annunziato, Francesco; Anselmo, Achille; Bacher, Petra; Baldari, Cosima T; Bari, Sudipto; Barnaba, Vincenzo; ... (2019). Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European journal of immunology, 49(10), pp. 1457-1973. Wiley-VCH 10.1002/eji.201970107

Castro Dias, Mariana; Coisne, Caroline; Baden, Pascale; Enzmann, Gaby; Garrett, Lillian; Becker, Lore; Hölter, Sabine M; Hrabě de Angelis, Martin; Deutsch, Urban; Engelhardt, Britta (2019). Claudin-12 is not required for blood-brain barrier tight junction function. Fluids and barriers of the CNS, 16(1), p. 30. BioMed Central 10.1186/s12987-019-0150-9

Vranova, Martina; Friess, Mona C; Haghayegh Jahromi, Neda; Collado-Diaz, Victor; Vallone, Angela; Hagedorn, Olivia; Jadhav, Maria; Willrodt, Ann-Helen; Polomska, Anna; Leroux, Jean-Christophe; Proulx, Steven Thomas; Halin, Cornelia (2019). Opposing roles of endothelial and leukocyte-expressed IL-7Rα in the regulation of psoriasis-like skin inflammation. Scientific reports, 9(1), p. 11714. Springer Nature 10.1038/s41598-019-48046-y

Castro Dias, Mariana; Coisne, Caroline; Lazarevic, Ivana; Baden, Pascale; Hata, Masaki; Iwamoto, Noriko; Ferreira Francisco, David Miguel; Vanlandewijck, Michael; He, Liqun; Baier, Felix A.; Stroka, Deborah; Bruggmann, Rémy; Lyck, Ruth; Enzmann, Gaby; Deutsch, Urban; Betsholtz, Christer; Furuse, Mikio; Tsukita, Shoichiro; Engelhardt, Britta (2019). Publisher Correction: Claudin-3-deficient C57BL/6J mice display intact brain barriers. Scientific reports, 9(1), p. 10702. Springer Nature 10.1038/s41598-019-43511-0

Bachmann, Samia B; Gsponer, Denise; Montoya-Zegarra, Javier A; Schneider, Martin; Scholkmann, Felix; Tacconi, Carlotta; Noerrelykke, Simon F; Proulx, Steven T.; Detmar, Michael (2019). A Distinct Role of the Autonomic Nervous System in Modulating the Function of Lymphatic Vessels under Physiological and Tumor-Draining Conditions. Cell reports, 27(11), 3305-3314.e13. Elsevier 10.1016/j.celrep.2019.05.050

Lenti, Elisa; Bianchessi, Silvia; Proulx, Steven Thomas; Palano, Maria Teresa; Genovese, Luca; Raccosta, Laura; Spinelli, Antonello; Drago, Denise; Andolfo, Annapaola; Alfano, Massimo; Petrova, Tatiana V; Mukenge, Sylvain; Russo, Vincenzo; Brendolan, Andrea (2019). Therapeutic Regeneration of Lymphatic and Immune Cell Functions upon Lympho-organoid Transplantation. Stem cell reports, 12(6), pp. 1260-1268. Elsevier 10.1016/j.stemcr.2019.04.021

Bachmann, Samia B; Proulx, Steven Thomas; He, Yuliang; Ries, Miriam; Detmar, Michael (2019). Differential effects of anaesthesia on the contractility of lymphatic vessels in vivo. The journal of physiology, 597(11), pp. 2841-2852. The Physiological Society 10.1113/JP277254

Mohsen, Mona O.; Heath, Matthew D; Cabral-Miranda, Gustavo; Lipp, Cyrill; Zeltins, Andris; Sande, Marcos; Stein, Jens V.; Riether, Carsten; Rösti, Elisa; Zha, Lisha; Engeroff, Paul; El-Turabi, Aadil; Kundig, Thomas M; Vogel, Monique; Skinner, Murray A; Speiser, Daniel E; Knuth, Alexander; Kramer, Matthias F; Bachmann, Martin F. (2019). Correction to: Vaccination with nanoparticles combined with micro-adjuvants protects against cancer. Journal for immunotherapy of cancer, 7(1), p. 137. BioMed Central 10.1186/s40425-019-0616-y

Mohsen, Mona O.; Heath, Matthew D; Cabral-Miranda, Gustavo; Lipp, Cyrill; Zeltins, Andris; Sande, Marcos; Stein, Jens V.; Riether, Carsten; Rösti, Elisa; Zha, Lisha; Engeroff, Paul; El-Turabi, Aadil; Kundig, Thomas M; Vogel, Monique; Skinner, Murray A; Speiser, Daniel E; Knuth, Alexander; Kramer, Matthias F; Bachmann, Martin F. (2019). Vaccination with nanoparticles combined with micro-adjuvants protects against cancer. Journal for immunotherapy of cancer, 7(1), p. 114. BioMed Central 10.1186/s40425-019-0587-z

Tietz, Silvia; Engelhardt, Britta (2019). Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo. Journal of visualized experiments(145) MYJoVE Corporation 10.3791/59249

Enzmann, Gaby; Adelfio, Roberto; Godel, Aurélie; Haghayegh Jahromi, Neda; Tietz, Silvia; Burgener, Sabrina S.; Deutsch, Urban; Wekerle, Hartmut; Benarafa, Charaf; Engelhardt, Britta (2019). The Genetic Background of Mice Influences the Effects of Cigarette Smoke on Onset and Severity of Experimental Autoimmune Encephalomyelitis. International journal of molecular sciences, 20(6) Molecular Diversity Preservation International MDPI 10.3390/ijms20061433

Polomska, Anna K; Proulx, Steven Thomas; Brambilla, Davide; Fehr, Daniel; Bonmarin, Mathias; Brändli, Simon; Meboldt, Mirko; Steuer, Christian; Vasileva, Tsvetina; Reinke, Nils; Leroux, Jean-Christophe; Detmar, Michael (2019). Minimally invasive method for the point-of-care quantification of lymphatic vessel function. JCI insight, 4(4) JCI Insight 10.1172/jci.insight.126515

Jordão, Marta Joana Costa; Sankowski, Roman; Brendecke, Stefanie M; Sagar, PhD; Locatelli, Giuseppe; Tai, Yi-Heng; Tay, Tuan Leng; Schramm, Eva; Armbruster, Stephan; Hagemeyer, Nora; Groß, Olaf; Mai, Dominic; Çiçek, Özgün; Falk, Thorsten; Kerschensteiner, Martin; Grün, Dominic; Prinz, Marco (2019). Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation. Science, 363(6425) American Association for the Advancement of Science 10.1126/science.aat7554

Mota Castro Dias, Mariana; Coisne, Caroline Marie; Lazarevic, Ivana; Baden, Pascale; Hata, Masaki; Iwamoto, Noriko; Francisco, David Miguel Ferreira; Vanlandewijck, Michael; He, Liqun; Baier, Felix Alexander; Keogh-Stroka, Deborah M.; Bruggmann, Rémy; Lyck, Ruth; Enzmann, Gaby; Deutsch, Urban; Betsholtz, Christer; Furuse, Mikio; Tsukita, Shoichiro; Engelhardt, Britta (2019). Claudin-3-deficient C57BL/6J mice display intact brain barriers. Scientific Reports, 9(1), p. 203. Nature Publishing Group 10.1038/s41598-018-36731-3

Ma, Qiaoli; Ries, Miriam; Decker, Yann; Müller, Andreas; Riner, Chantal; Bücker, Arno; Fassbender, Klaus; Detmar, Michael; Proulx, Steven T. (2019). Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain. Acta neuropathologica, 137(1), pp. 151-165. Springer-Verlag 10.1007/s00401-018-1916-x

Mossu, Adrien; Rosito, Maria; Khire, Tejas; Li Chung, Hung; Nishihara, Hideaki; Gruber, Isabelle; Luke, Emma; Dehouck, Lucie; Sallusto, Federica; Gosselet, Fabien; McGrath, James L; Engelhardt, Britta (2019). A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood-brain barrier under flow. Journal of cerebral blood flow and metabolism, 39(3), pp. 395-410. Sage 10.1177/0271678X18820584

Wimmer, Isabella; Tietz, Silvia; Nishihara, Hideaki; Deutsch, Urban; Sallusto, Federica; Gosselet, Fabien; Lyck, Ruth; Muller, William A; Lassmann, Hans; Engelhardt, Britta (2019). PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation. Frontiers in immunology, 10, p. 711. Frontiers Research Foundation 10.3389/fimmu.2019.00711

Yoon, Sun-Young; Dieterich, Lothar C; Karaman, Sinem; Proulx, Steven T.; Bachmann, Samia B; Sciaroni, Carol; Detmar, Michael (2019). An important role of cutaneous lymphatic vessels in coordinating and promoting anagen hair follicle growth. PLoS ONE, 14(7), e0220341. Public Library of Science 10.1371/journal.pone.0220341

2018

Schwager, Simon; Renner, Silvana; Hemmerle, Teresa; Karaman, Sinem; Proulx, Steven T.; Fetz, Roman; Golding-Ochsenbein, Alexandra Michaela; Probst, Philipp; Halin, Cornelia; Neri, Dario; Detmar, Michael (2018). Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation. JCI insight, 3(23) JCI Insight 10.1172/jci.insight.124850

Enzmann, Gaby; Pavlidou, Sofia; Vaas, Markus; Klohs, Jan; Engelhardt, Britta (2018). ICAM-1 C57BL/6 Mice Are Not Protected from Experimental Ischemic Stroke. Translational stroke research, 9(6), pp. 608-621. Springer 10.1007/s12975-018-0612-4

Lamas-Murua, Miguel; Stolp, Bettina; Kaw, Sheetal; Thoma, Judith; Tsopoulidis, Nikolaos; Trautz, Birthe; Ambiel, Ina; Reif, Tatjana; Arora, Sakshi; Imle, Andrea; Tibroni, Nadine; Wu, Jingxia; Cui, Guoliang; Stein, Jens Volker; Tanaka, Motomu; Lyck, Ruth; Fackler, Oliver T (2018). HIV-1 Nef Disrupts CD4 T Lymphocyte Polarity, Extravasation, and Homing to Lymph Nodes via Its Nef-Associated Kinase Complex Interface. Journal of immunology, 201(9), pp. 2731-2743. American Association of Immunologists 10.4049/jimmunol.1701420

Evangelopoulos, Maria Eleftheria; Miclea, Andrei; Schrewe, Lisa; Briner, Myriam; Salmen, Anke; Engelhardt, Britta; Huwiler, Andrea; Chan, Andrew; Hoepner, Robert (2018). Frequency and clinical characteristics of Multiple Sclerosis rebounds after withdrawal of Fingolimod. CNS neuroscience & therapeutics, 24(10), pp. 984-986. Wiley 10.1111/cns.12992

Tietz, Silvia; Périnat, Therese; Greene, Gretchen Thompson; Enzmann, Gaby; Deutsch, Urban; Adams, Ralf; Imhof, Beat; Aurrand-Lions, Michel; Engelhardt, Britta (2018). Lack of junctional adhesion molecule (JAM)-B ameliorates experimental autoimmune encephalomyelitis. Brain, behavior, and immunity, 73, pp. 3-20. Elsevier 10.1016/j.bbi.2018.06.014

Laufer, Julia M; Lyck, Ruth; Legler, Daniel F (2018). ZAP70 expression enhances chemokine-driven chronic lymphocytic leukemia cell migration and arrest by valency regulation of integrins. FASEB journal, 32(9), pp. 4824-4835. Federation of American Societies for Experimental Biology 10.1096/fj.201701452RR

Locatelli, Giuseppe; Theodorou, Delphine; Kendirli, Arek; Jordão, Marta Joana Costa; Staszewski, Ori; Phulphagar, Kshiti; Cantuti-Castelvetri, Ludovico; Dagkalis, Athanasios; Bessis, Alain; Simons, Mikael; Meissner, Felix; Prinz, Marco; Kerschensteiner, Martin (2018). Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model. Nature neuroscience, 21(9), pp. 1196-1208. Nature America 10.1038/s41593-018-0212-3

Steinemann, Nina; Kuhle, Jens; Calabrese, Pasquale; Kesselring, Jürg; Disanto, Giulio; Merkler, Doron; Pot, Caroline; Ajdacic-Gross, Vladeta; Rodgers, Stephanie; Puhan, Milo Alan; von Wyl, Viktor (2018). The Swiss Multiple Sclerosis Registry (SMSR): study protocol of a participatory, nationwide registry to promote epidemiological and patient-centered MS research. BMC neurology, 18(1), p. 111. BioMed Central 10.1186/s12883-018-1118-0

Ma, Qiaoli; Dieterich, Lothar C; Ikenberg, Kristian; Bachmann, Samia B; Mangana, Johanna; Proulx, Steven T.; Amann, Valerie C; Levesque, Mitchell P; Dummer, Reinhard; Baluk, Peter; McDonald, Donald M; Detmar, Michael (2018). Unexpected contribution of lymphatic vessels to promotion of distant metastatic tumor spread. Science Advances, 4(8), eaat4758. American Association for the Advancement of Science 10.1126/sciadv.aat4758

Pizzagalli, Diego Ulisse; Farsakoglu, Yagmur; Palomino-Segura, Miguel; Palladino, Elisa; Sintes, Jordi; Marangoni, Francesco; Mempel, Thorsten R; Koh, Wan Hon; Murooka, Thomas T; Thelen, Flavian; Stein, Jens V; Pozzi, Giuseppe; Thelen, Marcus; Krause, Rolf; Gonzalez, Santiago Fernandez (2018). Leukocyte Tracking Database, a collection of immune cell tracks from intravital 2-photon microscopy videos. Scientific data, 5(180129), p. 180129. Nature Publishing Group 10.1038/sdata.2018.129

Moalli, Federica; Ficht, Xenia; Germann, Philipp; Vladymyrov, Mykhailo; Stolp, Bettina; de Vries, Ingrid; Lyck, Ruth; Balmer, Jasmin Maria; Fiocchi, Amleto; Kreutzfeldt, Mario; Merkler, Doron; Iannacone, Matteo; Ariga, Akitaka; Stoffel, Michael Hubert; Sharpe, James; Bähler, Martin; Sixt, Michael; Diz-Muñoz, Alba; Stein, Jens Volker (2018). The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8 T cells. Journal of experimental medicine, 215(7), pp. 1869-1890. Rockefeller University Press 10.1084/jem.20170896

Hons, Miroslav; Kopf, Aglaja; Hauschild, Robert; Leithner, Alexander; Gaertner, Florian; Abe, Jun; Renkawitz, Jörg; Stein, Jens V; Sixt, Michael (2018). Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells. Nature immunology, 19(6), pp. 606-616. Nature Publishing Group 10.1038/s41590-018-0109-z

García-Martín, Ana B; Zwicky, Pascale; Gruber, Thomas; Matti, Christoph; Moalli, Federica; Stein, Jens Volker; Francisco, David; Enzmann, Gaby; Levesque, Mitchell P; Hewer, Ekkehard; Lyck, Ruth (2018). VLA-4 mediated adhesion of melanoma cells on the blood-brain barrier is the critical cue for melanoma cell intercalation and barrier disruption. Journal of cerebral blood flow and metabolism, 39(10), pp. 1995-2010. Sage 10.1177/0271678X18775887

Ficht, Xenia Maria; Stolp, Bettina; Thelen, Flavian; Stein, Jens Volker (2018). Preparation of Murine Submandibular Salivary Gland for Upright Intravital Microscopy. Journal of visualized experiments(135) MYJoVE Corporation 10.3791/57283

Roth, Stefan; Singh, Vikramjeet; Tiedt, Steffen; Schindler, Lisa; Huber, Georg; Geerlof, Arie; Antoine, Daniel J; Anfray, Antoine; Orset, Cyrille; Gauberti, Maxime; Fournier, Antoine; Holdt, Lesca M; Harris, Helena Erlandsson; Engelhardt, Britta; Bianchi, Marco E; Vivien, Denis; Haffner, Christof; Bernhagen, Jürgen; Dichgans, Martin and Liesz, Arthur (2018). Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke. Science translational medicine, 10(432) American Association for the Advancement of Science 10.1126/scitranslmed.aao1313

Engelhardt, Britta (2018). Cluster: barriers of the central nervous system. Acta neuropathologica, 135(3), pp. 307-310. Springer-Verlag 10.1007/s00401-018-1816-0

Ghersi-Egea, Jean-François; Strazielle, Nathalie; Catala, Martin; Silva-Vargas, Violeta; Doetsch, Fiona; Engelhardt, Britta (2018). Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease. Acta neuropathologica, 135(3), pp. 337-361. Springer-Verlag 10.1007/s00401-018-1807-1

Bouattour, Mohamed; Raymond, Eric; Qin, Shukui; Cheng, Ann-Lii; Stammberger, Uz; Locatelli, Giuseppe; Faivre, Sandrine (2018). Recent developments of c-Met as a therapeutic target in hepatocellular carcinoma. Hepatology, 67(3), pp. 1132-1149. Wiley 10.1002/hep.29496

Uster, Stephanie Sarah; Matos Coelho, Fernanda; Aeberli, Daniel; Stein, Jens Volker; Hofstetter, Wilhelm; Engelhardt, Britta; Seitz, Michael (2018). TNFα blockade mediates bone protection in antigen-induced arthritis by reducing osteoclast precursor supply. Bone, 107, pp. 56-65. Elsevier 10.1016/j.bone.2017.10.020

Enzmann, Gaby; Kargaran, Soghra; Engelhardt, Britta (2018). Ischemia-reperfusion injury in stroke: impact of the brain barriers and brain immune privilege on neutrophil function. Therapeutic advances in neurological disorders, 11, p. 1756286418794184. Sage 10.1177/1756286418794184

Megrelis, Laura; El Ghoul, Elyas; Moalli, Federica; Versapuech, Margaux; Cassim, Shamir; Ruef, Nora Maria; Stein, Jens Volker; Mangeney, Marianne; Delon, Jérôme (2018). Fam65b Phosphorylation Relieves Tonic RhoA Inhibition During T Cell Migration. Frontiers in immunology, 9, p. 2001. Frontiers Research Foundation 10.3389/fimmu.2018.02001

Barreto de Albuquerque, Juliana; Silva Dos Santos, Danielle; Stein, Jens Volker; de Meis, Juliana (2018). Oral Versus Intragastric Inoculation: Similar Pathways of Experimental Infection? From Target Tissues, Parasite Evasion, and Immune Response. Frontiers in immunology, 9, p. 1734. Frontiers Research Foundation 10.3389/fimmu.2018.01734

Bachmann, Samia B; Detmar, Michael; Proulx, Steven T. (2018). Visualization and Measurement of Lymphatic Function In Vivo. Methods in molecular biology, 1846, pp. 197-211. Springer 10.1007/978-1-4939-8712-2_13

2017

Martin, Katherine R; Pederzoli-Ribeil, Magali; Pacreau, Emeline; Burgener, Sabrina S; Dahdah, Albert; Candalh, Céline; Lauret, Evelyne; Foretz, Marc; Mouthon, Luc; Lucas, Bruno; Thieblemont, Nathalie; Benarafa, Charaf; Launay, Pierre; Witko-Sarsat, Véronique (2017). Transgenic Mice Expressing Human Proteinase 3 Exhibit Sustained Neutrophil-Associated Peritonitis. Journal of immunology, 199(11), pp. 3914-3924. American Association of Immunologists 10.4049/jimmunol.1601522

Llovera, Gemma; Benakis, Corinne; Enzmann, Gaby; Cai, Ruiyao; Arzberger, Thomas; Ghasemigharagoz, Alireza; Mao, Xiang; Malik, Rainer; Lazarevic, Ivana; Liebscher, Sabine; Ertürk, Ali; Meissner, Lilja; Vivien, Denis; Haffner, Christof; Plesnila, Nikolaus; Montaner, Joan; Engelhardt, Britta; Liesz, Arthur (2017). The choroid plexus is a key cerebral invasion route for T cells after stroke. Acta neuropathologica, 134(6), pp. 851-868. Springer 10.1007/s00401-017-1758-y

Wu, Yi-Long; Soo, Ross Andrew; Locatelli, Giuseppe; Stammberger, Uz; Scagliotti, Giorgio; Park, Keunchil (2017). Does c-Met remain a rational target for therapy in patients with EGFR TKI-resistant non-small cell lung cancer? Cancer treatment reviews, 61, pp. 70-81. Elsevier 10.1016/j.ctrv.2017.10.003

Ma, Qiaoli; Ineichen, Benjamin V; Detmar, Michael; Proulx, Steven T. (2017). Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice. Nature communications, 8(1), p. 1434. Springer Nature 10.1038/s41467-017-01484-6

Zaretsky, Irina; Atrakchi, Ofir; Mazor, Roei D; Stoler-Barak, Liat; Biram, Adi; Feigelson, Sara W; Gitlin, Alexander D; Engelhardt, Britta; Shulman, Ziv (2017). ICAMs support B cell interactions with T follicular helper cells and promote clonal selection. The Journal of experimental medicine, 214(11), pp. 3435-3448. Rockefeller Univ. Press 10.1084/jem.20171129

Mathias, Amandine; Perriot, Sylvain; Canales, Mathieu; Blatti, Claudia; Gaubicher, Coline; Schluep, Myriam; Engelhardt, Britta; Du Pasquier, Renaud (2017). Impaired T-cell migration to the CNS under fingolimod and dimethyl fumarate. Neurology: Neuroimmunology and Neuroinflammation, 4(6), e401. Wolters Kluwer Health 10.1212/NXI.0000000000000401

Daneman, Richard; Engelhardt, Britta (2017). Brain barriers in health and disease. Neurobiology of disease, 107, pp. 1-3. Elsevier 10.1016/j.nbd.2017.05.008

Mager, Lukas Franz; Kölzer, Viktor Hendrik; Stuber Roos, Regula; Thoo Sin Lang, Lester; Keller, Irene; Köck, Ivonne; Langenegger, Maya; Simillion, Cedric; Pfister, Simona P; Faderl, Martin Richard; Genitsch Gratwohl, Vera; Tcymbarevich, Irina; Juillerat, Pascal; Li, Xiaohong; Xia, Yu; Karamitopoulou, Evanthia; Lyck, Ruth; Zlobec, Inti; Hapfelmeier, Siegfried Hektor; Bruggmann, Rémy; ... (2017). The ESRP1-GPR137 axis contributes to intestinal pathogenesis. eLife, 6 eLife Sciences Publications 10.7554/eLife.28366

Gousopoulos, Epameinondas; Proulx, Steven T; Bachmann, Samia B; Dieterich, Lothar C; Scholl, Jeannette; Karaman, Sinem; Bianchi, Roberta; Detmar, Michael (2017). An Important Role of VEGF-C in Promoting Lymphedema Development. Journal of investigative dermatology, 137(9), pp. 1995-2004. Elsevier 10.1016/j.jid.2017.04.033

Vaas, Markus; Enzmann, Gaby; Périnat, Therese; Siler, Ulrich; Reichenbach, Janine; Licha, Kai; Kipar, Anja; Rudin, Markus; Engelhardt, Britta; Klohs, Jan (2017). Non-invasive near-infrared fluorescence imaging of the neutrophil response in a mouse model of transient cerebral ischaemia. Journal of cerebral blood flow and metabolism, 37(8), pp. 2833-2847. Nature Publishing Group 10.1177/0271678X16676825

Lyck, Ruth; Lécuyer, Marc-André; Abadier, Michael Magdy Labib; Wyss, Christof B.; Matti, Christoph; Rosito, Maria; Enzmann, Gaby; Zeis, Thomas; Michel, Laure; García Martín, Ana B; Sallusto, Federica; Gosselet, Fabien; Deutsch, Urban; Weiner, Joshua A.; Schaeren-Wiemers, Nicole; Prat, Alexandres; Engelhardt, Britta (2017). ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood–brain barrier. Journal of cerebral blood flow and metabolism, 37(8), pp. 2894-2909. Nature Publishing Group 10.1177/0271678X16678639

Moore, Thomas L; Hauser, Daniel; Gruber, Thomas; Rothen-Rutishauser, Barbara; Lattuada, Marco; Petri-Fink, Alke; Lyck, Ruth (2017). Cellular Shuttles: Monocytes/Macrophages Exhibit Transendothelial Transport of Nanoparticles under Physiological Flow. ACS applied materials & interfaces, 9(22), pp. 18501-18511. American Chemical Society 10.1021/acsami.7b03479

Bosch, Angela J T; Bolinger, Beatrice; Keck, Simone; Stepanek, Ondrej; Ozga, Aleksandra Joanna; Galati-Fournier, Virginie; Stein, Jens Volker; Palmer, Ed (2017). A minimum number of autoimmune T cells to induce autoimmunity? Cellular immunology, 316, pp. 21-31. 10.1016/j.cellimm.2017.03.002

Ackerknecht, Markus; Gollmer, Kathrin; Germann, Philipp; Ficht, Xenia Maria; Abe, Jun; Fukui, Yoshinori; Swoger, Jim; Ripoll, Jorge; Sharpe, James; Stein, Jens Volker (2017). Antigen Availability and DOCK2-Driven Motility Govern CD4\mathplusT Cell Interactions with Dendritic Cells In Vivo. Journal of immunology, 199(2), pp. 520-530. American Association of Immunologists 10.4049/jimmunol.1601148

Mohsen, Mona O; Gomes, Ariane C; Cabral-Miranda, Gustavo; Krüger, Caroline Claire; Leoratti, Fabiana M S; Stein, Jens Volker; Bachmann, Martin (2017). Delivering adjuvants and antigens in separate nanoparticles eliminates the need of physical linkage for effective vaccination. Journal of controlled release, 251, pp. 92-100. Elsevier 10.1016/j.jconrel.2017.02.031

Atangana, Etienne; Schneider, Ulf C; Blecharz, Kinga; Magrini, Salima; Wagner, Josephin; Nieminen-Kelhä, Melina; Kremenetskaia, Irina; Heppner, Frank L; Engelhardt, Britta; Vajkoczy, Peter (2017). Intravascular Inflammation Triggers Intracerebral Activated Microglia and Contributes to Secondary Brain Injury After Experimental Subarachnoid Hemorrhage (eSAH). Translational stroke research, 8(2), pp. 144-156. Springer 10.1007/s12975-016-0485-3

Engelhardt, Britta; Vajkoczy, Peter; Weller, Roy O (2017). The movers and shapers in immune privilege of the CNS. Nature immunology, 18(2), pp. 123-131. Nature Publishing Group 10.1038/ni.3666

Lécuyer, Marc-André; Saint-Laurent, Olivia; Bourbonnière, Lyne; Larouche, Sandra; Larochelle, Catherine; Michel, Laure; Charabati, Marc; Abadier, Michael Magdy Labib; Zandee, Stephanie; Haghayegh Jahromi, Neda; Gowing, Elizabeth; Pittet, Camille; Lyck, Ruth; Engelhardt, Britta; Prat, Alexandre (2017). Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 114(4), E524-E533. National Academy of Sciences NAS 10.1073/pnas.1614336114

Teijeira, Alvaro; Hunter, Morgan C; Russo, Erica; Proulx, Steven T; Frei, Thomas; Debes, Gudrun F; Coles, Marc; Melero, Ignacio; Detmar, Michael; Rouzaut, Ana; Halin, Cornelia (2017). T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions. Cell reports, 18(4), pp. 857-865. Cell Press 10.1016/j.celrep.2016.12.078

Köchl, Robert; Thelen, Flavian; Vanes, Lesley; Brazão, Tiago F; Fountain, Kathryn; Xie, Jian; Huang, Chou-Long; Lyck, Ruth; Stein, Jens Volker; Tybulewicz, Victor L J (2017). Corrigendum: WNK1 kinase balances T cell adhesion versus migration in vivo. Nature immunology, 18(2), p. 246. Nature Publishing Group 10.1038/ni0217-246a

Benarafa, Charaf; Simon, Hans-Uwe (2017). Role of granule proteases in the life and death of neutrophils. Biochemical and biophysical research communications, 482(3), pp. 473-481. Academic Press 10.1016/j.bbrc.2016.11.086

Proulx, Steven T; Ma, Qiaoli; Andina, Diana; Leroux, Jean-Christophe; Detmar, Michael (2017). Quantitative measurement of lymphatic function in mice by noninvasive near-infrared imaging of a peripheral vein. JCI insight, 2(1), pp. 1-13. JCI Insight 10.1172/jci.insight.90861

Cui, Jihong; Hollmén, Maija; Li, Lina; Chen, Yong; Proulx, Steven T; Reker, Daniel; Schneider, Gisbert; Detmar, Michael (2017). New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate. OncoTarget, 8(1), pp. 1007-1022. Impact Journals LLC 10.18632/oncotarget.13537

Bianchi, Roberta; Russo, Erica; Bachmann, Samia B; Proulx, Steven T; Sesartic, Marko; Smaadahl, Nora; Watson, Steve P; Buckley, Christopher D; Halin, Cornelia; Detmar, Michael (2017). Postnatal Deletion of Podoplanin in Lymphatic Endothelium Results in Blood Filling of the Lymphatic System and Impairs Dendritic Cell Migration to Lymph Nodes. Arteriosclerosis, thrombosis, and vascular biology, 37(1), pp. 108-117. American Heart Association 10.1161/ATVBAHA.116.308020

Haghayegh Jahromi, Neda; Tardent, Heidi; Enzmann, Gaby; Deutsch, Urban; Kawakami, Naoto; Bittner, Stefan; Vestweber, Dietmar; Zipp, Frauke; Stein, Jens Volker; Engelhardt, Britta (2017). A Novel Cervical Spinal Cord Window Preparation Allows for Two-Photon Imaging of T-Cell Interactions with the Cervical Spinal Cord Microvasculature during Experimental Autoimmune Encephalomyelitis. Frontiers in immunology, 8, p. 406. 10.3389/fimmu.2017.00406

Pavlicek, David; Krebs, Jörg; Capossela, Simona; Bertolo, Alessandro; Engelhardt, Britta; Pannek, Jürgen; Stoyanov, Jivko (2017). Immunosenescence in persons with spinal cord injury in relation to urinary tract infections -a cross-sectional study. Immunity & ageing, 14(22), p. 22. BioMed Central 10.1186/s12979-017-0103-6

Cossarizza, Andrea; Chang, Hyun-Dong; Radbruch, Andreas; Akdis, Mübeccel; Andrä, Immanuel; Annunziato, Francesco; Bacher, Petra; Barnaba, Vincenzo; Battistini, Luca; Bauer, Wolfgang M; Baumgart, Sabine; Becher, Burkhard; Beisker, Wolfgang; Berek, Claudia; Blanco, Alfonso; Borsellino, Giovanna; Boulais, Philip E; Brinkman, Ryan R; Büscher, Martin; Busch, Dirk H; ... (2017). Guidelines for the use of flow cytometry and cell sorting in immunological studies. European journal of immunology, 47(10), pp. 1584-1797. Wiley-VCH 10.1002/eji.201646632

Abadier, Michael Magdy Labib; Lyck, Ruth (2017). Pathways across the blood-brain barrier. In: Lyck, Ruth; Enzmann, Gaby (eds.) The Blood Brain Barrier and Inflammation. Progress in Inflammation Research (pp. 187-211). Springer 10.1007/978-3-319-45514-3_9

Friese-Hamim, Manja; Bladt, Friedhelm; Locatelli, Giuseppe; Stammberger, Uz; Blaukat, Andree (2017). The selective c-Met inhibitor tepotinib can overcome epidermal growth factor receptor inhibitor resistance mediated by aberrant c-Met activation in NSCLC models. American journal of cancer research, 7(4), pp. 962-972. e-Century Publishing Corporation

Gousopoulos, Epameinondas; Karaman, Sinem; Proulx, Steven T; Leu, Kristin; Buschle, Dorina; Detmar, Michael (2017). High-Fat Diet in the Absence of Obesity Does Not Aggravate Surgically Induced Lymphoedema in Mice. European surgical research, 58(3-4), pp. 180-192. Karger 10.1159/000461579

2016

Stoeckle, Christina; Geering, Barbara; Yousefi, Shida; Rožman, Saša; Andina, Nicola; Benarafa, Charaf; Simon, Hans-Uwe (2016). RhoH is a negative regulator of eosinophilopoiesis. Cell death and differentiation, 23(12), pp. 1961-1972. Nature Publishing Group 10.1038/cdd.2016.73

Giese, Madleen; Turiello, Nadine; Molenda, Nicole; Palesch, David; Meid, Annika; Schroeder, Roman; Basilico, Paola; Benarafa, Charaf; Halatsch, Marc-Eric; Zimecki, Michal; Westhoff, Mike-Andrew; Wirtz, Christian Rainer; Burster, Timo (2016). Exogenous cathepsin G upregulates cell surface MHC class I molecules on immune and glioblastoma cells. OncoTarget, 7(46), pp. 74602-74611. Impact Journals LLC 10.18632/oncotarget.12980

Ataca, Dalya; Caikovski, Marian; Piersigilli, Alessandra; Moulin, Alexandre; Benarafa, Charaf; Earp, Sarah E; Guri, Yakir; Kostic, Corinne; Arsenijvic, Yvan; Soininen, Raija; Apte, Suneel S; Brisken, Cathrin (2016). Adamts18 deletion results in distinct developmental defects and provides a model for congenital disorders of lens, lung, and female reproductive tract development. Biology open BiO, 5(11), pp. 1585-1594. Company of Biologists 10.1242/bio.019711

Ozga, Aleksandra J; Moalli, Federica; Abe, Jun; Swoger, Jim; Sharpe, James; Zehn, Dietmar; Kreutzfeldt, Mario; Merkler, Doron; Ripoll, Jorge; Stein, Jens Volker (2016). pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion. The Journal of experimental medicine, 213(12), pp. 2811-2829. Rockefeller Univ. Press 10.1084/jem.20160206

Vladymyrov, Mykhailo; Abe, Jun; Moalli, Federica; Stein, Jens Volker; Ariga, Akitaka (2016). Real-time tissue offset correction system for intravital multiphoton microscopy. Journal of immunological methods, 438, pp. 35-41. Elsevier 10.1016/j.jim.2016.08.004

Georgiev, Hristo; Ravens, Inga; Benarafa, Charaf; Förster, Reinhold; Bernhardt, Günter (2016). Distinct gene expression patterns correlate with developmental and functional traits of iNKT subsets. Nature communications, 7, p. 13116. Nature Publishing Group 10.1038/ncomms13116

Gousopoulos, Epameinondas; Proulx, Steven T; Bachmann, Samia B; Scholl, Jeannette; Dionyssiou, Dimitris; Demiri, Efterpi; Halin, Cornelia; Dieterich, Lothar C; Detmar, Michael (2016). Regulatory T cell transfer ameliorates lymphedema and promotes lymphatic vessel function. JCI insight, 1(16), pp. 1-15. JCI Insight 10.1172/jci.insight.89081

Tietz, Silvia; Zwahlen, Marcel; Haghayegh Jahromi, Neda; Baden, Pascale; Lazarevic, Ivana; Enzmann, Gaby; Engelhardt, Britta (2016). Refined clinical scoring in comparative EAE studies does not enhance the chance to observe statistically significant differences. European journal of immunology, 46(10), pp. 2481-2483. Wiley-VCH 10.1002/eji.201546272

Ochsenbein, Alexandra M; Karaman, Sinem; Proulx, Steven T; Goldmann, Rhea; Chittazhathu, Jyothi; Dasargyri, Athanasia; Chong, Chloé; Leroux, Jean-Christophe; Stanley, E Richard; Detmar, Michael (2016). Regulation of lymphangiogenesis in the diaphragm by macrophages and VEGFR-3 signaling. Angiogenesis, 19(4), pp. 513-524. Springer Netherlands 10.1007/s10456-016-9523-8

Köchl, Robert; Thelen, Flavian; Vanes, Lesley; Brazão, Tiago F; Fountain, Kathryn; Xie, Jian; Huang, Chou-Long; Lyck, Ruth; Stein, Jens Volker; Tybulewicz, Victor L J (2016). WNK1 kinase balances T cell adhesion versus migration in vivo. Nature immunology, 17(9), pp. 1075-1083. Nature Publishing Group 10.1038/ni.3495

Engelhardt, Britta; Carare, Roxana O; Bechmann, Ingo; Flügel, Alexander; Laman, Jon D; Weller, Roy O (2016). Vascular, glial, and lymphatic immune gateways of the central nervous system. Acta neuropathologica, 132(3), pp. 317-338. Springer 10.1007/s00401-016-1606-5

Martin, Roland; Sospedra, Mireia; Rosito, Maria; Engelhardt, Britta (2016). Current multiple sclerosis treatments have improved our understanding of MS autoimmune pathogenesis. European journal of immunology, 46(9), pp. 2078-2090. Wiley-VCH 10.1002/eji.201646485

Rudolph, Henriette; Klopstein, Armelle; Gruber, Isabelle Manuela; Blatti, Claudia; Lyck, Ruth; Engelhardt, Britta (2016). Postarrest stalling rather than crawling favors CD8(+) over CD4(+) T-cell migration across the blood-brain barrier under flow in vitro. European journal of immunology, 46(9), pp. 2187-2203. Wiley-VCH 10.1002/eji.201546251

Burgener, Sabrina; Baumann, Mathias; Basilico, Paola; Remold-O'Donnell, Eileen; Touw, Ivo P; Benarafa, Charaf (2016). Myeloid conditional deletion and transgenic models reveal a threshold for the neutrophil survival factor Serpinb1. Biological chemistry, 397(9), pp. 897-905. De Gruyter 10.1515/hsz-2016-0132

Fan, Zhichao; McArdle, Sara; Marki, Alex; Mikulski, Zbigniew; Gutierrez, Edgar; Engelhardt, Britta; Deutsch, Urban; Ginsberg, Mark; Groisman, Alex; Ley, Klaus (2016). Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis. Nature communications, 7, p. 12658. Nature Publishing Group 10.1038/ncomms12658

Stein, Jens Volker; Moalli, Federica; Ackerknecht, Markus (2016). Basic Rules of T Cell Migration. In: Donnadieu, Emmanuel (ed.) Defects in T cell Trafficking and Resistance to Cancer Immunotherapy. Resistance to Targeted Anti-Cancer Therapeutics: Vol. 9 (pp. 1-19). Springer 10.1007/978-3-319-42223-7_1

Modregger, Peter; Cremona, Tiziana Patrizia; Benarafa, Charaf; Schittny, Johannes C; Olivo, Alessandro; Endrizzi, Marco (2016). Small angle x-ray scattering with edge-illumination. Scientific Reports, 6(30940), p. 30940. Nature Publishing Group 10.1038/srep30940

Gousopoulos, Epameinondas; Proulx, Steven T; Scholl, Jeannette; Uecker, Maja; Detmar, Michael (2016). Prominent Lymphatic Vessel Hyperplasia with Progressive Dysfunction and Distinct Immune Cell Infiltration in Lymphedema. American journal of pathology, 186(8), pp. 2193-2203. Elsevier 10.1016/j.ajpath.2016.04.006

Novkovic, Mario; Onder, Lucas; Cupovic, Jovana; Abe, Jun; Bomze, David; Cremasco, Viviana; Scandella, Elke; Stein, Jens Volker; Bocharov, Gennady; Turley, Shannon J; Ludewig, Burkhard (2016). Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality. PLoS biology, 14(7), e1002515. Public Library of Science 10.1371/journal.pbio.1002515

Goldmann, Tobias; Wieghofer, Peter; Jordão, Marta Joana Costa; Prutek, Fabiola; Hagemeyer, Nora; Frenzel, Kathrin; Amann, Lukas; Staszewski, Ori; Kierdorf, Katrin; Krueger, Martin; Locatelli, Giuseppe; Hochgerner, Hannah; Zeiser, Robert; Epelman, Slava; Geissmann, Frederic; Priller, Josef; Rossi, Fabio M V; Bechmann, Ingo; Kerschensteiner, Martin; Linnarsson, Sten; ... (2016). Origin, fate and dynamics of macrophages at central nervous system interfaces. Nature immunology, 17(7), pp. 797-805. Nature Publishing Group 10.1038/ni.3423

Christiansen, Ailsa J; Dieterich, Lothar C; Ohs, Isabel; Bachmann, Samia B; Bianchi, Roberta; Proulx, Steven T; Hollmén, Maija; Aebischer, David; Detmar, Michael (2016). Lymphatic endothelial cells attenuate inflammation via suppression of dendritic cell maturation. OncoTarget, 7(26), pp. 39421-39435. Impact Journals LLC 10.18632/oncotarget.9820

Carevic, M; Öz, H; Fuchs, K; Laval, J; Schroth, C; Frey, N; Hector, A; Bilich, T; Haug, M; Schmidt, A; Autenrieth, S E; Bucher, K; Beer-Hammer, S; Gaggar, A; Kneilling, M; Benarafa, Charaf; Gao, J L; Murphy, P M; Schwarz, S; Moepps, B; ... (2016). CXCR1 Regulates Pulmonary Anti-Pseudomonas Host Defense. Journal of innate immunity, 8(4), pp. 362-373. Karger 10.1159/000444125

Zanotti, L; Angioni, R; Calì, B; Soldani, C; Ploia, C; Moalli, Federica; Gargesha, M; D'Amico, G; Elliman, S; Tedeschi, G; Maffioli, E; Negri, A; Zacchigna, S; Sarukhan, A; Stein, Jens Volker; Viola, A (2016). Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1. Leukemia, 30(5), pp. 1143-1154. Nature Publishing Group 10.1038/leu.2016.33

Petrovich, Ekaterina; Feigelson, Sara W; Stoler-Barak, Liat; Hatzav, Miki; Solomon, Adam; Bar-Shai, Amir; Ilan, Neta; Li, Jin-Ping; Engelhardt, Britta; Vlodavsky, Israel; Alon, Ronen (2016). Lung ICAM-1 and ICAM-2 support spontaneous intravascular effector lymphocyte entrapment but are not required for neutrophil entrapment or emigration inside endotoxin-inflamed lungs. FASEB journal, 30(5), pp. 1767-1778. Federation of American Societies for Experimental Biology 10.1096/fj.201500046

Abe, Jun; Ozga, Aleksandra Joanna; Swoger, Jim; Sharpe, James; Ripoll, Jorge; Stein, Jens Volker (2016). Light sheet fluorescence microscopy for in situ cell interaction analysis in mouse lymph nodes. Journal of immunological methods, 431, pp. 1-10. Elsevier 10.1016/j.jim.2016.01.015

Fujikawa, Yuuta; Roma, Leticia P; Sobotta, Mirko C; Rose, Adam J; Diaz, Mauricio Berriel; Locatelli, Giuseppe; Breckwoldt, Michael O; Misgeld, Thomas; Kerschensteiner, Martin; Herzig, Stephan; Müller-Decker, Karin; Dick, Tobias P (2016). Mouse redox histology using genetically encoded probes. Science signaling, 9(419), rs1. American Association for the Advancement of Science 10.1126/scisignal.aad3895

Chong, Chloé; Scholkmann, Felix; Bachmann, Samia B; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael; Proulx, Steven T (2016). In vivo visualization and quantification of collecting lymphatic vessel contractility using near-infrared imaging. Scientific Reports, 6, p. 22930. Nature Publishing Group 10.1038/srep22930

Dasargyri, Athanasia; Hervella, Pablo; Christiansen, Ailsa; Proulx, Steven T; Detmar, Michael; Leroux, Jean-Christophe (2016). Findings questioning the involvement of Sigma-1 receptor in the uptake of anisamide-decorated particles. Journal of controlled release, 224, pp. 229-238. Elsevier 10.1016/j.jconrel.2016.01.021

Brambilla, Davide; Proulx, Steven T; Marschalkova, Patrizia; Detmar, Michael; Leroux, Jean-Christophe (2016). Microneedles for the Noninvasive Structural and Functional Assessment of Dermal Lymphatic Vessels. Small, 12(8), pp. 1053-1061. Wiley-VCH 10.1002/smll.201503093

Ochsenbein, Alexandra M; Karaman, Sinem; Proulx, Steven T; Berchtold, Michaela; Jurisic, Giorgia; Stoeckli, Esther T; Detmar, Michael (2016). Endothelial cell-derived semaphorin 3A inhibits filopodia formation by blood vascular tip cells. Development, 143(4), pp. 589-594. Company of Biologists Limited 10.1242/dev.127670

Feretti, MT; Merlini, M; Späni, C; Gericke, C; Schweizer, N; Enzmann, Gaby; Engelhardt, Britta; Kulic, L; Suter, T; Nitsch, RM (2016). T-cell brain infiltration and immature antigen-presenting cells in transgenic models of Alzheimer’s disease-like cerebral amyloidosis. Brain, behavior, and immunity, 54, pp. 211-225. Elsevier 10.1016/j.bbi.2016.02.009

Escobedo, Noelia; Proulx, Steven T; Karaman, Sinem; Dillard, Miriam E; Johnson, Nicole; Detmar, Michael; Oliver, Guillermo (2016). Restoration of lymphatic function rescues obesity in Prox1-haploinsufficient mice. JCI insight, 1(2), pp. 1-17. JCI Insight 10.1172/jci.insight.85096

Imeri, Faik; Schwalm, Stephanie; Lyck, Ruth; Zivkovic, Aleksandra; Stark, Holger; Engelhardt, Britta; Pfeilschifter, Josef; Huwiler, Andrea (2016). Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology, 105, pp. 341-350. Elsevier 10.1016/j.neuropharm.2016.01.031

Mundt, Sarah; Engelhardt, Britta; Kirk, Christopher J; Groettrup, Marcus; Basler, Michael (2016). Inhibition and deficiency of the immunoproteasome subunit LMP7 attenuates LCMV-induced meningitis. European journal of immunology, 46(1), pp. 104-113. Wiley-VCH 10.1002/eji.201545578

Sreeramkumar, Vinatha; Hons, Miroslav; Punzón, Carmen; Stein, Jens Volker; Sancho, David; Fresno, Manuel; Cuesta, Natalia (2016). Efficient T-cell priming and activation requires signaling through prostaglandin E2 (EP) receptors. Immunology and cell biology, 94(1), pp. 39-51. Nature Publishing Group 10.1038/icb.2015.62

Lopes Pinheiro, Melissa A; Kooij, Gijs; Mizee, Mark R; Kamermans, Alwin; Enzmann, Gaby; Lyck, Ruth; Schwaninger, Markus; Engelhardt, Britta; de Vries, Helga E (2016). Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke. Biochimica et biophysica acta - molecular basis of disease, 1862(3), pp. 461-471. Elsevier 10.1016/j.bbadis.2015.10.018

Lazarevic, Ivana; Engelhardt, Britta (2016). Modeling immune functions of the mouse blood-cerebrospinal fluid barrier in vitro: primary rather than immortalized mouse choroid plexus epithelial cells are suited to study immune cell migration across this brain barrier. Fluids and barriers of the CNS, 13(2), p. 2. BioMed Central 10.1186/s12987-016-0027-0

2015

Alonso, Angelika; Eisele, Philipp; Ebert, Anne D; Griebe, Martin; Engelhardt, Britta; Szabo, Kristina; Hennerici, Michael G; Gass, Achim (2015). Leptomeningeal contrast enhancement and blood-CSF barrier dysfunction in aseptic meningitis. Neurology: Neuroimmunology and Neuroinflammation, 2(6), e164. Wolters Kluwer Health 10.1212/NXI.0000000000000164

Martin-Blondel, Guillaume; Pignolet, Béatrice; Tietz, Silvia; Yshii, Lidia; Gebauer, Christina; Périnat, Therese; Van Weddingen, Isabelle; Blatti, Claudia; Engelhardt, Britta; Liblau, Roland (2015). Migration of encephalitogenic CD8 T cells into the central nervous system is dependent on the α4β1-integrin. European journal of immunology, 45(12), pp. 3302-3312. Wiley-VCH 10.1002/eji.201545632

Benarafa, Charaf; Wolf, Marlene (2015). CXCL14: the Swiss army knife chemokine. OncoTarget, 6(33), pp. 34065-34066. Oncotarget: Impact Journals LLC 10.18632/oncotarget.6040

Tang, Fengyuan; Gill, Jason; Ficht, Xenia Maria; Barthlott, Thomas; Cornils, Hauke; Schmitz-Rohmer, Debora; Hynx, Debby; Zhou, Dawang; Zhang, Lei; Xue, Gongda; Grzmil, Michal; Yang, Zhongzhou; Hergovich, Alexander; Hollaender, Georg A; Stein, Jens Volker; Hemmings, Brian A; Matthias, Patrick (2015). The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility. Science signaling, 8(397), ra100. American Association for the Advancement of Science 10.1126/scisignal.aab2425

Broggini, Thomas; Czabanka, Marcus; Piffko, Andras; Harms, Christoph; Hoffmann, Christian; Mrowka, Ralf; Wenke, Frank; Deutsch, Urban; Grötzinger, Carsten; Vajkoczy, Peter (2015). ICAM1 depletion reduces spinal metastasis formation in vivo and improves neurological outcome. European spine journal, 24(10), pp. 2173-2181. Springer 10.1007/s00586-015-3811-7

Karaman, Sinem; Buschle, Dorina; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael; Proulx, Steven T (2015). Decline of lymphatic vessel density and function in murine skin during aging. Angiogenesis, 18(4), pp. 489-498. Springer Netherlands 10.1007/s10456-015-9479-0

Basilico, Paola; Cremona, Tiziana Patrizia; Oevermann, Anna; Piersigilli, Alessandra; Benarafa, Charaf (2015). Cigarette Smoke Exposure Increases Myeloid Cell Production and Lung Bacterial Clearance in Mice. American journal of respiratory cell and molecular biology, 54(3), pp. 424-435. American Lung Association 10.1165/rcmb.2015-0017OC

Wälchli, Thomas; Wacker, Andrin; Frei, Karl; Regli, Luca; Schwab, Martin E; Hoerstrup, Simon P; Gerhardt, Holger; Engelhardt, Britta (2015). Wiring the Vascular Network with Neural Cues: A CNS Perspective. Neuron, 87(2), pp. 271-296. Cell Press 10.1016/j.neuron.2015.06.038

Aspelund, Aleksanteri; Antila, Salli; Proulx, Steven T; Karlsen, Tine Veronica; Karaman, Sinem; Detmar, Michael; Wiig, Helge; Alitalo, Kari (2015). A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. The Journal of experimental medicine, 212(7), pp. 991-999. Rockefeller Univ. Press 10.1084/jem.20142290

Li, Xue; Martinez-Lozano Sinues, Pablo; Dallmann, Robert; Bregy, Lukas; Hollmén, Maija; Proulx, Steven; Brown, Steven A; Detmar, Michael; Kohler, Malcolm; Zenobi, Renato (2015). Drug Pharmacokinetics Determined by Real-Time Analysis of Mouse Breath. Angewandte Chemie (International ed.), 54(27), pp. 7815-7818. Wiley-VCH 10.1002/anie.201503312

Dai, Chen; Basilico, Paola; Cremona, Tiziana Patrizia; Collins, Paul; Moser, Bernhard; Benarafa, Charaf; Wolf, Marlene (2015). CXCL14 Displays Antimicrobial Activity against Respiratory Tract Bacteria and Contributes to Clearance of Streptococcus pneumoniae Pulmonary Infection. Journal of immunology, 194(12), pp. 5980-5989. American Association of Immunologists 10.4049/jimmunol.1402634

Staat, Christian; Coisne, Caroline Marie; Dabrowski, Sebastian; Stamatovic, Svetlana M; Andjelkovic, Anuska V; Wolburg, Hartwig; Engelhardt, Britta; Blasig, Ingolf E (2015). Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers. Biomaterials, 54, pp. 9-20. Elsevier 10.1016/j.biomaterials.2015.03.007

Tietz, Silvia; Engelhardt, Britta (2015). Brain barriers: Crosstalk between complex tight junctions and adherens junctions. Journal of cell biology, 209(4), pp. 493-506. Rockefeller Institute Press 10.1083/jcb.201412147

Locatelli, Giuseppe; Baggiolini, Arianna; Schreiner, Bettina; Palle, Pushpalatha; Waisman, Ari; Becher, Burkhard; Buch, Thorsten (2015). Mature oligodendrocytes actively increase in vivo cytoskeletal plasticity following CNS damage. Journal of neuroinflammation, 12(62), p. 62. BioMed Central 10.1186/s12974-015-0271-2

van Geffen, Johanna P; Kleinegris, Marie-Claire; Verdoold, Remco; Baaten, Constance C F M J; Cosemans, Judith M E M; Ten Cate, Hugo; Roest, Mark; de Laat, Bas; Clemetson, Kenneth John; Heemskerk, Johan W M (2015). Normal platelet activation profile in patients with peripheral arterial disease on aspirin. Thrombosis research, 135(3), pp. 513-520. Elsevier 10.1016/j.thromres.2014.12.029

Rozman, Sasa; Yousefi, Shida; Oberson, Kevin; Kaufmann, Thomas; Benarafa, Charaf; Simon, Hans-Uwe (2015). The generation of neutrophils in the bone marrow is controlled by autophagy. Cell death and differentiation, 22(3), pp. 445-456. Nature Publishing Group 10.1038/cdd.2014.169

Kruger, Philipp; Saffarzadeh, Mona; Weber, Alexander N R; Rieber, Nikolaus; Radsak, Markus; von Bernuth, Horst; Benarafa, Charaf; Roos, Dirk; Skokowa, Julia; Hartl, Dominik (2015). Neutrophils: Between host defence, immune modulation, and tissue injury. PLoS pathogens, 11(3), e1004651. Public Library of Science 10.1371/journal.ppat.1004651

Eisele, Philipp; Griebe, Martin; Szabo, Kristina; Wolf, Marc E; Alonso, Angelika; Engelhardt, Britta; Hennerici, Michael G; Gass, Achim (2015). Investigation of leptomeningeal enhancement in MS: A postcontrast FLAIR MRI study. Neurology, 84(8), pp. 770-775. Lippincott Williams & Wilkins 10.1212/WNL.0000000000001286

Abadier, Michael Magdy Labib; Haghayegh Jahromi, Neda; Cardoso Alves, Ludmila; Boscacci, Rémy; Vestweber, Dietmar; Barnum, Scott; Deutsch, Urban; Engelhardt, Britta; Lyck, Ruth (2015). Cell surface levels of endothelial ICAM-1 influence the transcellular or paracellular T-cell diapedesis across the blood-brain barrier. European journal of immunology, 45(4), pp. 1043-1058. Wiley-VCH 10.1002/eji.201445125

Lyck, Ruth; Enzmann, Gaby (2015). The physiological roles of ICAM-1 and ICAM-2 in neutrophil migration into tissues. Current opinion in hematology, 22(1), pp. 53-59. Wolters Kluwer Lippincott Williams & Wilkins 10.1097/MOH.0000000000000103

Moalli, Federica; Proulx, Steven T; Schwendener, Reto; Detmar, Michael; Schlapbach, Christoph; Stein, Jens Volker (2015). Intravital and whole-organ imaging reveals capture of melanoma-derived antigen by lymph node subcapsular macrophages leading to widespread deposition on follicular dendritic cells. Frontiers in immunology, 6(114), p. 114. Frontiers Research Foundation 10.3389/fimmu.2015.00114

Stein, Jens Volker (2015). T Cell Motility as Modulator of Interactions with Dendritic Cells. Frontiers in immunology, 6, p. 559. Frontiers Research Foundation 10.3389/fimmu.2015.00559

Li, Hai; Limenitakis, Julien Periclis Jean; Fuhrer, Tobias; Geuking, Markus; Lawson, Melissa A; Wyss, Madeleine; Brugiroux, Sandrine; Keller, Irene; Macpherson, Jamie A; Rupp, Sandra; Stolp, Bettina; Stein, Jens Volker; Stecher, Bärbel; Sauer, Uwe; McCoy, Kathleen; Macpherson, Andrew (2015). The outer mucus layer hosts a distinct intestinal microbial niche. Nature communications, 6, p. 8292. Nature Publishing Group 10.1038/ncomms9292

Ackerknecht, Markus; Hauser, Mark A; Legler, Daniel F; Stein, Jens Volker (2015). In vivo TCR Signaling in CD4(+) T Cells Imprints a Cell-Intrinsic, Transient Low-Motility Pattern Independent of Chemokine Receptor Expression Levels, or Microtubular Network, Integrin, and Protein Kinase C Activity. Frontiers in immunology, 6, p. 297. Frontiers Research Foundation 10.3389/fimmu.2015.00297

Benarafa, Charaf (2015). Tumor-induced inflammation alters neutrophil phenotype and disease progression. Breast cancer research, 17(1), p. 135. BioMed Central Ltd. 10.1186/s13058-015-0644-6

Benarafa, Charaf (2015). Regulation of Neutrophil Serine Proteases by Intracellular Serpins. In: Geiger, Margarethe; Wahlmüller, Felix; Furtmüller, Margareta (eds.) The Serpin Family. Proteins with Multiple Functions in Health and Disease (pp. 59-76). Cham: Springer 10.1007/978-3-319-22711-5_5

Schreiner, Bettina; Ingold-Heppner, Barbara; Pehl, Debora; Locatelli, Giuseppe; Berrit-Schönthaler, Helia; Becher, Burkhard (2015). Deletion of Jun proteins in adult oligodendrocytes does not perturb cell survival, or myelin maintenance in vivo. PLoS ONE, 10(3), e0120454. Public Library of Science 10.1371/journal.pone.0120454

Bianchi, Roberta; Teijeira, Alvaro; Proulx, Steven T; Christiansen, Ailsa J; Seidel, Catharina D; Rülicke, Thomas; Mäkinen, Taija; Hägerling, René; Halin, Cornelia; Detmar, Michael (2015). A transgenic Prox1-Cre-tdTomato reporter mouse for lymphatic vessel research. PLoS ONE, 10(4), e0122976. Public Library of Science 10.1371/journal.pone.0122976

2014

Moalli, Federica; Cupovic, Jovana; Thelen, Flavian; Halbherr, Pascal; Fukui, Yoshinori; Narumiya, Shuh; Ludewig, Burkhard; Stein, Jens Volker (2014). Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4+ T cell-dendritic cell interactions. The Journal of experimental medicine, 211(13), pp. 2507-2517. Rockefeller Univ. Press 10.1084/jem.20140137

Lee, Kit M; Danuser, Renzo; Stein, Jens Volker; Graham, Delyth; Nibbs, Robert J B; Graham, Gerard J (2014). The chemokine receptors ACKR2 and CCR2 reciprocally regulate lymphatic vessel density. EMBO journal, 33(21), pp. 2564-2580. Nature Publishing Group 10.15252/embj.201488887

Steiner, Esther; Enzmann, Gaby; Lyck, Ruth; Lin, Shuo; Rüegg, Markus A; Kröger, Stephan; Engelhardt, Britta (2014). The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions. Cell and tissue research, 358(2), pp. 465-479. Springer 10.1007/s00441-014-1969-7

Liu, Ju; Deutsch, Urban; Fung, Iris; Lobe, Corrinne G (2014). Conditional and inducible transgene expression in endothelial and hematopoietic cells using Cre/loxP and tetracycline-off systems. Experimental and therapeutic medicine, 8(5), pp. 1351-1356. Spandidos Publ. 10.3892/etm.2014.1965

Liu, Ju; Dong, Fengyun; Fung, Iris; Chen, Edwin; Allen, Thaddeus D; Deutsch, Urban; Lobe, Corrinne G (2014). Postnatal Notch1 activation induces T‑cell malignancy in conditional and inducible mouse models. International journal of oncology, 45(5), pp. 1997-2004. Spandidos Publications 10.3892/ijo.2014.2626

Waber-Wenger, Barbara; Forterre, Franck; Kuehni-Boghenbor, Kathrin; Danuser, Renzo; Stein, Jens Volker; Stoffel, Michael Hubert (2014). Sensory innervation of the dorsal longitudinal ligament and the meninges in the lumbar spine of the dog. Histochemistry and cell biology, 142(4), pp. 433-447. Springer 10.1007/s00418-014-1218-x

Imeri, Faik; Fallegger, Daniel; Zivkovic, Aleksandra; Schwalm, Stephanie; Enzmann, Gaby; Blankenbach, Kira; Meyer zu Heringdorf, Dagmar; Homann, Thomas; Kleuser, Burkhard; Pfeilschifter, Josef; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2014). Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice. Neuropharmacology, 85, pp. 314-327. Elsevier 10.1016/j.neuropharm.2014.05.012

Aubé, Benoit; Lévesque, Sébastien A; Paré, Alexandre; Chamma, Émilie; Kébir, Hania; Gorina Mendiz, Roser; Lécuyer, Marc-André; Alvarez, Jorge I; De Koninck, Yves; Engelhardt, Britta; Prat, Alexandre; Côté, Daniel; Lacroix, Steve (2014). Neutrophils mediate blood-spinal cord barrier disruption in demyelinating neuroinflammatory diseases. Journal of immunology, 193(5), pp. 2438-2454. American Association of Immunologists 10.4049/jimmunol.1400401

Liu, Ju; Deutsch, Urban; Jeong, James; Lobe, Corrinne G (2014). Constitutive notch signaling in adult transgenic mice inhibits bFGF-induced angiogenesis and blocks ovarian follicle development. Genesis, 52(9), pp. 809-816. Wiley-Liss 10.1002/dvg.22790

Abe, Jun; Shichino, Shigeyuki; Ueha, Satoshi; Hashimoto, Shin-ichi; Tomura, Michio; Inagaki, Yutaka; Stein, Jens Volker; Matsushima, Kouji (2014). Lymph node stromal cells negatively regulate antigen-specific CD4+ T cell responses. Journal of immunology, 193(4), pp. 1636-1644. American Association of Immunologists 10.4049/jimmunol.1302946

Sathiyanadan, Karthik; Coisne, Caroline Marie; Enzmann, Gaby; Deutsch, Urban; Engelhardt, Britta (2014). PSGL-1 and E/P-selectins are essential for T-cell rolling in inflamed CNS microvessels but dispensable for initiation of EAE. European journal of immunology, 44(8), pp. 2287-2294. Wiley-VCH 10.1002/eji.201344214

Weber, Benedikt; Robert, Jérôme; Ksiazek, Agnieszka; Wyss, Yves; Frese, Laura; Slamecka, Jaroslav; Kehl, Debora; Modregger, Peter; Peter, Silvia; Stampanoni, Marco; Proulx, Steven; Falk, Volkmar; Hoerstrup, Simon P (2014). Living-engineered valves for transcatheter venous valve repair. Tissue engineering. Part C, Methods, 20(6), pp. 451-463. Mary Ann Liebert 10.1089/ten.TEC.2013.0187

Navdaev, Alexey; Subramanian, Hariharan; Petunin, Alexey; Clemetson, Kenneth John; Gambaryan, Stepan; Walter, Ulrich (2014). Echicetin coated polystyrene beads: a novel tool to investigate GPIb-specific platelet activation and aggregation. PLoS ONE, 9(4), e93569. Public Library of Science 10.1371/journal.pone.0093569

Engelhardt, Britta; Liebner, Stefan (2014). Novel insights into the development and maintenance of the blood-brain barrier. Cell and tissue research, 355(3), pp. 687-699. Springer 10.1007/s00441-014-1811-2

Mayer, Jürgen; Robert-Moreno, Alexandre; Danuser, Renzo; Stein, Jens Volker; Sharpe, James; Swoger, Jim (2014). OPTiSPIM: integrating optical projection tomography in light sheet microscopy extends specimen characterization to nonfluorescent contrasts. Optics letters, 39(4), pp. 1053-1056. Optical Society of America 10.1364/OL.39.001053

Geering, Barbara; Stoeckle, Christina; Rozman, Sasa; Oberson, Kevin; Benarafa, Charaf; Simon, Hans-Uwe (2014). DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants. Journal of leukocyte biology, 95(2), pp. 293-303. Society for Leukocyte Biology 10.1189/jlb.0813462

Gorina Mendiz, Roser; Lyck, Ruth; Vestweber, Dietmar; Engelhardt, Britta (2014). β2 integrin-mediated crawling on endothelial ICAM-1 and ICAM-2 is a prerequisite for transcellular neutrophil diapedesis across the inflamed blood-brain barrier. Journal of immunology, 192(1), pp. 324-337. American Association of Immunologists 10.4049/jimmunol.1300858

de Witt, Susanne M; Swieringa, Frauke; Cavill, Rachel; Lamers, Moniek M E; van Kruchten, Roger; Mastenbroek, Tom; Baaten, Constance; Coort, Susan; Pugh, Nicholas; Schulz, Ansgar; Scharrer, Inge; Jurk, Kerstin; Zieger, Barbara; Clemetson, Kenneth John; Farndale, Richard W; Heemskerk, Johan W M; Cosemans, Judith M E M (2014). Identification of platelet function defects by multi-parameter assessment of thrombus formation. Nature communications, 5, p. 4257. Nature Publishing Group 10.1038/ncomms5257

Cecchelli, Romeo; Aday, Sezin; Sevin, Emmanuel; Almeida, Catarina; Culot, Maxime; Dehouck, Lucie; Coisne, Caroline Marie; Engelhardt, Britta; Dehouck, Marie-Pierre; Ferreira, Lino (2014). A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells. PLoS ONE, 9(6), e99733. Public Library of Science 10.1371/journal.pone.0099733

Minten, Carsten; Alt, Carsten; Gentner, Melanie; Frei, Elisabeth; Deutsch, Urban; Lyck, Ruth; Schaeren-Wiemers, Nicole; Rot, Antal; Engelhardt, Britta (2014). DARC shuttles inflammatory chemokines across the blood-brain barrier during autoimmune central nervous system inflammation. Brain, 137(Pt 5), pp. 1454-1469. Oxford University Press 10.1093/brain/awu045

Blum, Katrin S; Karaman, Sinem; Proulx, Steven T; Ochsenbein, Alexandra M; Luciani, Paola; Leroux, Jean-Christophe; Wolfrum, Christian; Detmar, Michael (2014). Chronic high-fat diet impairs collecting lymphatic vessel function in mice. PLoS ONE, 9(4), e94713. Public Library of Science 10.1371/journal.pone.0094713

2013

Proulx, Steven T; Luciani, Paola; Dieterich, Lothar C; Karaman, Sinem; Leroux, Jean-Christophe; Detmar, Michael (2013). Expansion of the lymphatic vasculature in cancer and inflammation: new opportunities for in vivo imaging and drug delivery. Journal of controlled release, 172(2), pp. 550-557. Elsevier 10.1016/j.jconrel.2013.04.027

Cremona, Tiziana P.; Tschanz, Stefan A.; von Garnier, Christophe; Benarafa, Charaf (2013). SerpinB1 deficiency is not associated with increased susceptibility to pulmonary emphysema in mice. American journal of physiology - lung cellular and molecular physiology, 305(12), L981-L989. American Physiological Society 10.1152/ajplung.00181.2013

Moretti, Federico A.; Moser, Markus; Lyck, Ruth; Abadier, Michael Magdy Labib; Ruppert, Raphael; Engelhardt, Britta; Fässler, Reinhard (2013). Kindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 110(42), pp. 17005-17010. National Academy of Sciences NAS 10.1073/pnas.1316032110

Iolyeva, Maria; Aebischer, David; Proulx, Steven T; Willrodt, Ann-Helen; Ecoiffier, Tatiana; Häner, Simone; Bouchaud, Grégory; Krieg, Carsten; Onder, Lucas; Ludewig, Burkhard; Santambrogio, Laura; Boyman, Onur; Chen, Lu; Finke, Daniela; Halin, Cornelia (2013). Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage. Blood, 122(13), pp. 2271-2281. American Society of Hematology 10.1182/blood-2013-01-478073

Paolinelli, Roberta; Corada, Monica; Ferrarini, Luca; Devraj, Kavi; Artus, Cédric; Czupalla, Cathrin J.; Rudini, Noemi; Maddaluno, Luigi; Papa, Eleanna; Engelhardt, Britta; Couraud, Pierre Olivier; Liebner, Stefan; Dejana, Elisabetta (2013). Wnt activation of immortalized brain endothelial cells as a tool for generating a standardized model of the blood brain barrier in vitro. PLoS ONE, 8(8), e70233. Public Library of Science 10.1371/journal.pone.0070233

Ziegler, Tilman; Horstkotte, Jan; Schwab, Claudia; Pfetsch, Vanessa; Weinmann, Karolina; Dietzel, Steffen; Rohwedder, Ina; Hinkel, Rabea; Gross, Lisa; Lee, Seungmin; Hu, Junhao; Soehnlein, Oliver; Franz, Wolfgang M.; Sperandio, Markus; Pohl, Ulrich; Thomas, Markus; Weber, Christian; Augustin, Hellmut G.; Fässler, Reinhard; Deutsch, Urban; ... (2013). Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis. Journal of clinical investigation, 123(8), pp. 3436-3445. American Society for Clinical Investigation 10.1172/JCI66549

Weber, Benedikt; Kehl, Debora; Bleul, Ulrich; Behr, Luc; Sammut, Sébastien; Frese, Laura; Ksiazek, Agnieszka; Achermann, Josef; Stranzinger, Gerald; Robert, Jérôme; Sanders, Bart; Sidler, Michele; Brokopp, Chad E.; Proulx, Steven T.; Frauenfelder, Thomas; Schoenauer, Roman; Emmert, Maximilian Y.; Falk, Volkmar; Hoerstrup, Simon P. (2013). In vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells. Journal of tissue engineering and regenerative medicine, 10(1), pp. 52-70. John Wiley & Sons 10.1002/term.1781

Alitalo, Annamari K; Proulx, Steven T; Karaman, Sinem; Aebischer, David; Martino, Stefania; Jost, Manuela; Schneider, Nicole; Bry, Maija; Detmar, Michael (2013). VEGF-C and VEGF-D blockade inhibits inflammatory skin carcinogenesis. Cancer research, 73(14), pp. 4212-4221. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-12-4539

Proulx, Steven T; Detmar, Michael (2013). Molecular mechanisms and imaging of lymphatic metastasis. Experimental cell research, 319(11), pp. 1611-1617. Elsevier 10.1016/j.yexcr.2013.03.009

Pérez-Rivero, Gema; Cascio, Graciela; Soriano, Silvia Fernández; Sanz, Álvaro Gil; de Guinoa, Julia Sáez; Rodríguez-Frade, José Miguel; Gomariz, Rosa P.; Holgado, Borja L.; Cabañas, Carlos; Carrasco, Yolanda R.; Stein, Jens Volker; Mellado, Mario (2013). Janus kinases 1 and 2 regulate chemokine-mediated integrin activation and naïve T-cell homing. European journal of immunology, 43(7), pp. 1745-1757. Wiley-VCH 10.1002/eji.201243178

Proulx, Steven T; Luciani, Paola; Christiansen, Ailsa; Karaman, Sinem; Blum, Katrin S; Rinderknecht, Matthias; Leroux, Jean-Christophe; Detmar, Michael (2013). Use of a PEG-conjugated bright near-infrared dye for functional imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasis. Biomaterials, 34(21), pp. 5128-5137. Elsevier 10.1016/j.biomaterials.2013.03.034

Proulx, Steven T; Luciani, Paola; Alitalo, Annamari; Mumprecht, Viviane; Christiansen, Ailsa J; Huggenberger, Reto; Leroux, Jean-Christophe; Detmar, Michael (2013). Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in vivo. Angiogenesis, 16(3), pp. 525-540. Springer Netherlands 10.1007/s10456-013-9332-2

Chai, Qian; Onder, Lucas; Scandella, Elke; Gil-Cruz, Cristina; Perez-Shibayama, Christian; Cupovic, Jovana; Danuser, Renzo; Sparwasser, Tim; Luther, Sanjiv A.; Thiel, Volker; Rülicke, Thomas; Stein, Jens Volker; Hehlgans, Thomas; Ludewig, Burkhard (2013). Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity. Immunity, 38(5), pp. 1013-1024. Cell Press 10.1016/j.immuni.2013.03.012

Matos Coelho, Fernanda; Natale, Daniela; Soriano, Silvia F.; Hons, Miroslav; Swoger, Jim; Mayer, Jürgen; Danuser, Renzo; Scandella, Elke; Pieczyk, Markus; Zerwes, Hans-Günter; Junt, Tobias; Sailer, Andreas W.; Ludewig, Burkhard; Sharpe, James; Figge, Marc Thilo; Stein, Jens Volker (2013). Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions. Blood, 121(20), pp. 4101-4109. American Society of Hematology 10.1182/blood-2012-10-465336

Baumann, Mathias; Pham, Christine T. N.; Benarafa, Charaf (2013). SerpinB1 is critical for neutrophil survival through cell-autonomous inhibition of cathepsin G. Blood, 121(19), pp. 3900-3907. The American Society of Hematology 10.1182/blood-2012-09-455022

Blum, Katrin S; Proulx, Steven T; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael (2013). Dynamics of lymphatic regeneration and flow patterns after lymph node dissection. Breast cancer research and treatment, 139(1), pp. 81-86. Springer 10.1007/s10549-013-2537-7

Kappelmayer, J.; Beke Debreceni, I.; Vida, A.; Antal-Szalmás, P.; Clemetson, Kenneth J.; Nagy Jr, B. (2013). Distinct effects of Re- and S-forms of LPS on modulating platelet activation. Journal of thrombosis and haemostasis, 11(4), pp. 775-778. Wiley-Blackwell 10.1111/jth.12151

Onder, Lucas; Danuser, Renzo; Scandella, Elke; Firner, Sonja; Chai, Qian; Hehlgans, Thomas; Stein, Jens Volker; Ludewig, Burkhard (2013). Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation. The Journal of experimental medicine, 210(3), pp. 465-473. Rockefeller Univ. Press 10.1084/jem.20121462

Enzmann, Gaby; Mysiorek, Caroline; Gorina, Roser; Cheng, Yu-Jung; Ghavampour, Sharang; Hannocks, Melanie-Jane; Prinz, Vincent; Dirnagl, Ulrich; Endres, Matthias; Prinz, Marco; Beschorner, Rudi; Harter, Patrick N.; Mittelbronn, Michel; Engelhardt, Britta; Sorokin, Lydia (2013). The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury. Acta neuropathologica, 125(3), pp. 395-412. Berlin: Springer-Verlag 10.1007/s00401-012-1076-3

Coisne, Caroline; Lyck, Ruth; Engelhardt, Britta (2013). Live cell imaging techniques to study T cell trafficking across the blood-brain barrier in vitro and in vivo. Fluids and barriers of the CNS, 10(1), p. 7. London: BioMed Central

Muldoon, Leslie L; Alvarez, Jorge I; Begley, David J; Boado, Ruben J; Del Zoppo, Gregory J; Doolittle, Nancy D; Engelhardt, Britta; Hallenbeck, John M; Lonser, Russell R; Ohlfest, John R; Prat, Alexandre; Scarpa, Maurizio; Smeyne, Richard J; Drewes, Lester R; Neuwelt, Edward A (2013). Immunologic privilege in the central nervous system and the blood-brain barrier. Journal of cerebral blood flow and metabolism, 33(1), pp. 13-21. New York, N.Y.: Nature Publishing Group 10.1038/jcbfm.2012.153

Martinelli, Sibylla; Chen, Emily J. H.; Clarke, Fiona; Lyck, Ruth; Affentranger, Sarah; Burkhardt, Janis K.; Niggli, Verena (2013). Ezrin/Radixin/Moesin proteins and flotillins cooperate to promote uropod formation in T cells. Frontiers in immunology, 4, p. 84. Frontiers Research Foundation 10.3389/fimmu.2013.00084

2012

Duong, Tam; Proulx, Steven T; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael; Koopman, Peter; Francois, Mathias (2012). Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice. Cancer research, 72(12), pp. 3105-3114. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-11-4026

Locatelli, Giuseppe; Wörtge, Simone; Buch, Thorsten; Ingold, Barbara; Frommer, Friederike; Sobottka, Bettina; Krüger, Martin; Karram, Khalad; Bühlmann, Claudia; Bechmann, Ingo; Heppner, Frank L; Waisman, Ari; Becher, Burkhard (2012). Primary oligodendrocyte death does not elicit anti-CNS immunity. Nature neuroscience, 15(4), pp. 543-550. Nature America 10.1038/nn.3062

Proulx, Steven T; Detmar, Michael (2012). Watching lymphatic vessels grow by making them glow. Cell research, 22(1), pp. 12-13. Nature Publishing Group 10.1038/cr.2011.191

Kronstein, Romy; Seebach, Jochen; Grossklaus, Sylvia; Minten, Carsten; Engelhardt, Britta; Drab, Marek; Liebner, Stefan; Arsenijevic, Yvan; Taha, Abdallah Abu; Afanasieva, Tatiana; Schnittler, Hans-Joachim (2012). Caveolin-1 opens endothelial cell junctions by targeting catenins. Cardiovascular research, 93(1), pp. 130-40. Oxford: Oxford University Press 10.1093/cvr/cvr256

Véliz Rodriguez, Tania; Moalli, Federica; Polentarutti, Nadia; Paroni, Moira; Bonavita, Eduardo; Anselmo, Achille; Nebuloni, Manuela; Mantero, Stefano; Jaillon, Sébastien; Bragonzi, Alessandra; Mantovani, Alberto; Riva, Federica; Garlanda, Cecilia (2012). Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection. Infection and immunity, 80(1), pp. 100-9. New York, N.Y.: American Society for Microbiology 10.1128/IAI.05695-11

Schlosser, Stefan; Dennler, Cyrill; Schweizer, Riccardo; Eberli, Daniel; Stein, Jens V; Enzmann, Volker; Giovanoli, Pietro; Erni, Dominique; Plock, Jan A (2012). Paracrine effects of mesenchymal stem cells enhance vascular regeneration in ischemic murine skin. Microvascular research, 83(3), pp. 267-75. Oxford: Elsevier 10.1016/j.mvr.2012.02.011

Nitschké, Maximilian; Aebischer, David; Abadier, Michael Magdy Labib; Haener, Simone; Lucic, Matije; Vigl, Benjamin; Luche, Hervé; Fehling, Hans Jörg; Biehlmaier, Oliver; Lyck, Ruth; Halin, Cornelia (2012). Differential requirement for ROCK in dendritic cell migration within lymphatic capillaries in steady-state and inflammation. Blood, 120(11), pp. 2249-58. Washington, D.C.: American Society of Hematology 10.1182/blood-2012-03-417923

Stolley, J Michael; Gong, Dapeng; Farley, Kalamo; Zhao, Picheng; Cooley, Jessica; Crouch, Erika C; Benarafa, Charaf; Remold-O'Donnell, Eileen (2012). Increased surfactant protein D fails to improve bacterial clearance and inflammation in serpinB1-/- mice. American journal of respiratory cell and molecular biology, 47(6), pp. 792-9. New York, N.Y.: American Lung Association 10.1165/rcmb.2012-0145OC

Wojtalla, Anna; Salm, Fabiana; Christiansen, Ditte G.; Cremona, Tiziana; Cwiek, Paulina; Shalaby, Tarek; Gross, Nicole; Grotzer, Michael A.; Arcaro, Alexandre (2012). Novel agents targeting the IGF-1R/PI3K pathway impair cell proliferation and survival in subsets of medulloblastoma and neuroblastoma. PLoS ONE, 7(10), e47109. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0047109

Ludewig, Burkhard; Stein, Jens V; Sharpe, James; Cervantes-Barragan, Luisa; Thiel, Volker; Bocharov, Gennady (2012). A global ”imaging” view on systems approaches in immunology. European journal of immunology, 42(12), pp. 3116-25. Weinheim: Wiley-VCH 10.1002/eji.201242508

Stolp, Bettina; Imle, Andrea; Coelho, Fernanda Matos; Hons, Miroslav; Gorina, Roser; Lyck, Ruth; Stein, Jens V; Fackler, Oliver T (2012). HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 109(45), pp. 18541-6. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.1204322109

Mayer, Jürgen; Swoger, Jim; Ozga, Aleksandra J; Stein, Jens V; Sharpe, James (2012). Quantitative measurements in 3-dimensional datasets of mouse lymph nodes resolve organ-wide functional dependencies. Computational and mathematical methods in medicine, 2012, p. 128431. London: Taylor & Francis 10.1155/2012/128431

Kumar, Varsha; Chyou, Susan; Stein, Jens V; Lu, Theresa T (2012). Optical projection tomography reveals dynamics of HEV growth after immunization with protein plus CFA and features shared with HEVs in acute autoinflammatory lymphadenopathy. Frontiers in immunology, 3, p. 282. Lausanne: Frontiers Research Foundation 10.3389/fimmu.2012.00282

Harada, Yosuke; Tanaka, Yoshihiko; Terasawa, Masao; Pieczyk, Markus; Habiro, Katsuyoshi; Katakai, Tomoya; Hanawa-Suetsugu, Kyoko; Kukimoto-Niino, Mutsuko; Nishizaki, Tomoko; Shirouzu, Mikako; Duan, Xuefeng; Uruno, Takehito; Nishikimi, Akihiko; Sanematsu, Fumiyuki; Yokoyama, Shigeyuki; Stein, Jens V; Kinashi, Tatsuo; Fukui, Yoshinori (2012). DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses. Blood, 119(19), pp. 4451-61. Washington, D.C.: American Society of Hematology 10.1182/blood-2012-01-407098

Wyss, Lena; Schäfer, Julia; Liebner, Stefan; Mittelbronn, Michel; Deutsch, Urban; Enzmann, Gaby; Adams, Ralf H.; Aurrand-Lions, Michel; Plate, Karl H.; Imhof, Beat A.; Engelhardt, Britta (2012). Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus. PLoS ONE, 7(9), e45619. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0045619

Lyck, Ruth; Engelhardt, Britta (2012). Going against the tide--how encephalitogenic T cells breach the blood-brain barrier. Journal of vascular research, 49(6), pp. 497-509. Basel: Karger 10.1159/000341232

Engelhardt, Britta; Ransohoff, Richard M (2012). Capture, crawl, cross: the T cell code to breach the blood-brain barriers. Trends in immunology, 33(12), pp. 579-89. Oxford: Elsevier Current Trends 10.1016/j.it.2012.07.004

Ransohoff, Richard M; Engelhardt, Britta (2012). The anatomical and cellular basis of immune surveillance in the central nervous system. Nature reviews - immunology, 12(9), pp. 623-35. London: Nature Publishing Group 10.1038/nri3265

Steiner, Esther; Enzmann, Gaby U; Lin, Shuo; Ghavampour, Sharang; Hannocks, Melanie-Jane; Zuber, Benoît; Rüegg, Markus A; Sorokin, Lydia; Engelhardt, Britta (2012). Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation. GLIA, 60(11), pp. 1646-59. Hoboken, N.J.: Wiley-Blackwell 10.1002/glia.22383

Sallusto, Federica; Impellizzieri, Daniela; Basso, Camilla; Laroni, Alice; Uccelli, Antonio; Lanzavecchia, Antonio; Engelhardt, Britta (2012). T-cell trafficking in the central nervous system. Immunological reviews, 248(1), pp. 216-27. Oxford: Wiley-Blackwell 10.1111/j.1600-065X.2012.01140.x

Mazzon, Cristina; Anselmo, Achille; Soldani, Cristiana; Cibella, Javier; Ploia, Cristina; Moalli, Federica; Burden, Steven J; Dustin, Michael L; Sarukhan, Adelaida; Viola, Antonella (2012). Agrin is required for survival and function of monocytic cells. Blood, 119(23), pp. 5502-11. Washington, D.C.: American Society of Hematology 10.1182/blood-2011-09-382812

Schneider, Henriette; Adams, Ortwin; Weiss, Christel; Merz, Ulrich; Schroten, Horst; Tenenbaum, Tobias (2012). Clinical Characteristics of Children with Viral Single- and Co-Infections and a Petechial Rash. Pediatric infectious disease journal, 32(5), e186-e191. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/INF.0b013e318280618d

Schneider, Henriette; Weber, Claudia Ellen; Schoeller, Julia; Steinmann, Ulrike; Borkowski, Julia; Ishikawa, Hiroshi; Findeisen, Peter; Adams, Ortwin; Doerries, Ruediger; Schwerk, Christian; Schroten, Horst; Tenenbaum, Tobias (2012). Chemotaxis of T-cells after infection of human choroid plexus papilloma cells with Echovirus 30 in an in vitro model of the blood-cerebrospinal fluid barrier. Virus research, 170(1-2), pp. 66-74. Amsterdam: Elsevier 10.1016/j.virusres.2012.08.019

Schneider, Henriette; Geginat, Gernot; Hogardt, Michael; Kramer, Alexandra; Dürken, Matthias; Schroten, Horst; Tenenbaum, Tobias (2012). Pseudomonas aeruginosa outbreak in a pediatric oncology care unit caused by an errant water jet into contaminated siphons. Pediatric infectious disease journal, 31(6), pp. 648-50. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/INF.0b013e31824d1a11

Meuwissen, Pieter J.; Stolp, Bettina; Iannucci, Veronica; Vermeire, Jolien; Naessens, Evelien; Saksela, Kalle; Geyer, Matthias; Vanham, Guido; Arien, Kevin K.; Fackler, Oliver T.; Verhasselt, Bruno (2012). Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function. Retrovirology, 9, p. 34. London: BioMed Central 10.1186/1742-4690-9-34

Wolf, Marlene; Moser, Bernhard (2012). Antimicrobial activities of chemokines: not just a side-effect? Frontiers in immunology, 3, p. 213. Lausanne: Frontiers Research Foundation 10.3389/fimmu.2012.00213

2011

Steiner, Oliver; Coisne, Caroline; Engelhardt, Britta; Lyck, Ruth (2011). Comparison of immortalized bEnd5 and primary mouse brain microvascular endothelial cells as in vitro blood-brain barrier models for the study of T cell extravasation. Journal of cerebral blood flow and metabolism, 31(1), pp. 315-27. New York, N.Y.: Nature Publishing Group 10.1038/jcbfm.2010.96

Bill, Ruben; Döring, Axinia; Deutsch, Urban; Engelhardt, Britta (2011). PSGL-1 is dispensible for the development of active experimental autoimmune encephalomyelitis in SJL/J mice. Journal of neuroimmunology, 232(1-2), pp. 207-8. Amsterdam: Elsevier 10.1016/j.jneuroim.2010.10.008

Brun-Heath, Isabelle; Ermonval, Myriam; Chabrol, Elodie; Xiao, Jinsong; Palkovits, Miklós; Lyck, Ruth; Miller, Florence; Couraud, Pierre-Olivier; Mornet, Etienne; Fonta, Caroline (2011). Differential expression of the bone and the liver tissue non-specific alkaline phosphatase isoforms in brain tissues. Cell and tissue research, 343(3), pp. 521-36. Heidelberg: Springer 10.1007/s00441-010-1111-4

Balmelli, Carole; Steiner, Esther; Moulin, Hervé; Peduto, Nadja; Herrmann, Brigitte; Summerfield, Artur; McCullough, Kenneth (2011). Porcine circovirus type 2 DNA influences cytoskeleton rearrangements in plasmacytoid and monocyte-derived dendritic cells. Immunology, 132(1), pp. 57-65. Oxford: Wiley-Blackwell 10.1111/j.1365-2567.2010.03339.x

Kaenel, Philip; Schwab, Caroline; Mülchi, Kathrin; Wotzkow Alvarez, Carlos; Andres, Anne-Catherine (2011). Preponderance of cells with stem cell characteristics in metastasising mouse mammary tumours induced by deregulated EphB4 and ephrin-B2 expression. International journal of oncology, 38(1), pp. 151-60. Athens: Spandidos Publications 10.3892/ijo_00000834

Lélu, Karine; Laffont, Sophie; Delpy, Laurent; Paulet, Pierre-Emmanuel; Périnat, Therese; Tschanz, Stefan A.; Pelletier, Lucette; Engelhardt, Britta; Guéry, Jean-Charles (2011). Estrogen Receptor α Signaling in T Lymphocytes Is Required for Estradiol-Mediated Inhibition of Th1 and Th17 Cell Differentiation and Protection against Experimental Autoimmune Encephalomyelitis. Journal of immunology, 187(5), pp. 2386-93. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1101578

Engelhardt, Britta (2011). Neuroscience. Blood-brain barrier differentiation. Science, 334(6063), pp. 1652-3. Washington, D.C.: American Association for the Advancement of Science 10.1126/science.1216853

Pfeiffer, Friederike; Schäfer, Julia; Lyck, Ruth; Makrides, Victoria; Brunner, Sarah; Schaeren-Wiemers, Nicole; Deutsch, Urban; Engelhardt, Britta (2011). Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis. Acta neuropathologica, 122(5), pp. 601-14. Berlin: Springer-Verlag 10.1007/s00401-011-0883-2

Engelhardt, Britta (2011). β1-integrin/matrix interactions support blood-brain barrier integrity. Journal of cerebral blood flow and metabolism, 31(10), pp. 1969-71. New York, N.Y.: Nature Publishing Group 10.1038/jcbfm.2011.98

Engelhardt, Britta; Coisne, Caroline (2011). Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castle. Fluids and barriers of the CNS, 8(1), p. 4. London: BioMed Central 10.1186/2045-8118-8-4

Döring, Axinia; Pfeiffer, Friederike; Meier, Matthias; Dehouck, Bénédicte; Tauber, Silke; Deutsch, Urban; Engelhardt, Britta (2011). TET inducible expression of the α4β7-integrin ligand MAdCAM-1 on the blood-brain barrier does not influence the immunopathogenesis of experimental autoimmune encephalomyelitis. European journal of immunology, 41(3), pp. 813-21. Weinheim: Wiley-VCH 10.1002/eji.201040912

Coisne, Caroline; Engelhardt, Britta (2011). Tight junctions in brain barriers during central nervous system inflammation. Antioxidants & redox signalling, 15(5), pp. 1285-303. Larchmont, N.Y.: Mary Ann Liebert 10.1089/ars.2011.3929

Greenwood, J; Heasman, S J; Alvarez, J I; Prat, A; Lyck, R; Engelhardt, B (2011). Review: leucocyte-endothelial cell crosstalk at the blood-brain barrier: a prerequisite for successful immune cell entry to the brain. Neuropathology & applied neurobiology, 37(1), pp. 24-39. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2990.2010.01140.x

Gong, Dapeng; Farley, Kalamo; White, Mitchell; Hartshorn, Kevan L; Benarafa, Charaf; Remold-O'Donnell, Eileen (2011). Critical role of serpinB1 in regulating inflammatory responses in pulmonary influenza infection. Journal of infectious diseases, 204(4), pp. 592-600. Cary, N.C.: Oxford University Press 10.1093/infdis/jir352

Benarafa, Charaf (2011). The SerpinB1 knockout mouse a model for studying neutrophil protease regulation in homeostasis and inflammation. Methods in enzymology, 499, pp. 135-148. New York, N.Y.: Academic Press 10.1016/B978-0-12-386471-0.00007-9

Fischer, Heinz; Scherz, Jennifer; Szabo, Sandra; Mildner, Michael; Benarafa, Charaf; Torriglia, Alicia; Tschachler, Erwin; Eckhart, Leopold (2011). DNase 2 is the main DNA-degrading enzyme of the stratum corneum. PLoS ONE, 6(3), e17581. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0017581

Benarafa, Charaf; LeCuyer, Tessa E; Baumann, Mathias; Stolley, James Michael; Cremona, Tiziana P; Remold-O'Donnell, Eileen (2011). SerpinB1 protects the mature neutrophil reserve in the bone marrow. Journal of leukocyte biology, 90(1), pp. 21-9. Bethesda, Md.: Society for Leukocyte Biology 10.1189/jlb.0810461

Zattoni, Michela; Mura, Maria Luisa; Deprez, Francine; Schwendener, Reto A; Engelhardt, Britta; Frei, Karl; Fritschy, Jean-Marc (2011). Brain infiltration of leukocytes contributes to the pathophysiology of temporal lobe epilepsy. Journal of neuroscience, 31(11), pp. 4037-50. Washington, D.C.: Society for Neuroscience 10.1523/JNEUROSCI.6210-10.2011

Soriano, Silvia F; Hons, Miroslav; Schumann, Kathrin; Kumar, Varsha; Dennier, Timo J; Lyck, Ruth; Sixt, Michael; Stein, Jens V (2011). In vivo analysis of uropod function during physiological T cell trafficking. Journal of immunology, 187(5), pp. 2356-64. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1100935

Moalli, Federica; Jaillon, Sebastien; Inforzato, Antonio; Sironi, Marina; Bottazzi, Barbara; Mantovani, Alberto; Garlanda, Cecilia (2011). Pathogen recognition by the long pentraxin PTX3. Journal of biomedicine and biotechnology, 2011, p. 830421. Akron, Ohio: Hindawi Pub. Corp. 10.1155/2011/830421

Moalli, Federica; Paroni, Moira; Véliz Rodriguez, Tania; Riva, Federica; Polentarutti, Nadia; Bottazzi, Barbara; Valentino, Sonia; Mantero, Stefano; Nebuloni, Manuela; Mantovani, Alberto; Bragonzi, Alessandra; Garlanda, Cecilia (2011). The therapeutic potential of the humoral pattern recognition molecule PTX3 in chronic lung infection caused by Pseudomonas aeruginosa. Journal of immunology, 186(9), pp. 5425-34. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1002035

Inforzato, A; Jaillon, S; Moalli, F; Barbati, E; Bonavita, E; Bottazzi, B; Mantovani, A; Garlanda, C (2011). The long pentraxin PTX3 at the crossroads between innate immunity and tissue remodelling. Tissue antigens, 77(4), pp. 271-82. Oxford: Wiley-Blackwell 10.1111/j.1399-0039.2011.01645.x

Criado, Enrique; Moalli, Federica; Polentarutti, Nadia; Albani, Elena; Morreale, Giovanna; Menduni, Francesca; Levi-Setti, Paolo Emanuele (2011). Experimental contamination assessment of a novel closed ultravitrification device. Fertility and sterility, 95(5), pp. 1777-9. New York, N.Y.: Elsevier 10.1016/j.fertnstert.2010.12.044

Garlanda, Cecilia; Bottazzi, Barbara; Moalli, Federica; Deban, Livija; Molla, Fabiola; Latini, Roberto; Mantovani, Alberto (2011). Pentraxins and atherosclerosis: the role of PTX3. Current pharmaceutical design, 17(1), pp. 38-46. Hilversum: Bentham Science Publishers 10.2174/138161211795049750

Lamana, Amalia; Martin, Pilar; de la Fuente, Hortensia; Martinez-Muñoz, Laura; Cruz-Adalia, Aranzazu; Ramirez-Huesca, Marta; Escribano, Cristina; Gollmer, Kathrin; Mellado, Mario; Stein, Jens V; Rodriguez-Fernandez, Jose Luis; Sanchez-Madrid, Francisco; del Hoyo, Gloria Martinez (2011). CD69 modulates sphingosine-1-phosphate-induced migration of skin dendritic cells. Journal of Investigative Dermatology, 131(7), pp. 1503-12. New York, N.Y.: Nature Publishing 10.1038/jid.2011.54

Stolp, Bettina; Fackler, Oliver T (2011). How HIV takes advantage of the cytoskeleton in entry and replication. Viruses, 3(4), pp. 293-311. Basel: Molecular Diversity Preservation International MDPI 10.3390/v3040293

Bennett-Guerrero, Elliott; Stolp, Bryant W (2011). Fiberoptic intubation. New England journal of medicine NEJM, 365(6), 574; author reply 575-6. Waltham, Mass.: Massachusetts Medical Society MMS 10.1056/NEJMc1106936#SA1

Bouchet, Jérôme; Basmaciogullari, Stéphane E; Chrobak, Pavel; Stolp, Bettina; Bouchard, Nathalie; Fackler, Oliver T; Chames, Patrick; Jolicoeur, Paul; Benichou, Serge; Baty, Daniel (2011). Inhibition of the Nef regulatory protein of HIV-1 by a single-domain antibody. Blood, 117(13), pp. 3559-68. Washington, D.C.: American Society of Hematology 10.1182/blood-2010-07-296749

2010

Mumprecht, Viviane; Honer, Michael; Vigl, Benjamin; Proulx, Steven T; Trachsel, Eveline; Kaspar, Manuela; Banziger-Tobler, Nadja E; Schibli, Roger; Neri, Dario; Detmar, Michael (2010). In vivo imaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography. Cancer research, 70(21), pp. 8842-8851. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-10-0896

Jurisic, Giorgia; Iolyeva, Maria; Proulx, Steven T; Halin, Cornelia; Detmar, Michael (2010). Thymus cell antigen 1 (Thy1, CD90) is expressed by lymphatic vessels and mediates cell adhesion to lymphatic endothelium. Experimental cell research, 316(17), pp. 2982-2992. Elsevier 10.1016/j.yexcr.2010.06.013

Huggenberger, Reto; Ullmann, Stefan; Proulx, Steven T; Pytowski, Bronislaw; Alitalo, Kari; Detmar, Michael (2010). Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation. The Journal of experimental medicine, 207(10), pp. 2255-2269. Rockefeller Univ. Press 10.1084/jem.20100559

Proulx, Steven T; Luciani, Paola; Derzsi, Stefanie; Rinderknecht, Matthias; Mumprecht, Viviane; Leroux, Jean-Christophe; Detmar, Michael (2010). Quantitative imaging of lymphatic function with liposomal indocyanine green. Cancer research, 70(18), pp. 7053-7062. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-10-0271

Papuga, M Owen; Proulx, Steven T; Kwok, Edmund; You, Zhigang; Rubery, Paul T; Dougherty, Paul E; Hilton, Matthew J; Awad, Hani A; Schwarz, Edward M (2010). Chronic axial compression of the mouse tail segment induces MRI bone marrow edema changes that correlate with increased marrow vasculature and cellularity. Journal of orthopaedic research, 28(9), pp. 1220-1228. Wiley 10.1002/jor.21103

Li, Jie; Kuzin, Igor; Moshkani, Safiehkhatoon; Proulx, Steven T; Xing, Lianping; Skrombolas, Denise; Dunn, Robert; Sanz, Iñaki; Schwarz, Edward M; Bottaro, Andrea (2010). Expanded CD23(+)/CD21(hi) B cells in inflamed lymph nodes are associated with the onset of inflammatory-erosive arthritis in TNF-transgenic mice and are targets of anti-CD20 therapy. Journal of immunology, 184(11), pp. 6142-6150. American Association of Immunologists 10.4049/jimmunol.0903489

Li, Dan; Gromov, Kirill; Proulx, Steven T; Xie, Chao; Li, Jie; Crane, Daniel P; Søballe, Kjeld; O'Keefe, Regis J; Awad, Hani A; Xing, Lianping; Schwarz, Edward M (2010). Effects of antiresorptive agents on osteomyelitis: novel insights into the pathogenesis of osteonecrosis of the jaw. Annals of the New York Academy of Sciences, 1192(1), pp. 84-94. Wiley 10.1111/j.1749-6632.2009.05210.x

Chadjichristos, C E; Scheckenbach, K E L; van Veen, T A B; Richani Sarieddine, M Z; de Wit, C; Yang, Z; Roth, I; Bacchetta, M; Viswambharan, H; Foglia, B; Dudez, T; van Kempen, M J A; Coenjaerts, F E J; Miquerol, L; Deutsch, U; Jongsma, H J; Chanson, M; Kwak, B R (2010). Endothelial-specific deletion of connexin40 promotes atherosclerosis by increasing CD73-dependent leukocyte adhesion. Circulation, 121(1), pp. 123-31. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCULATIONAHA.109.867176

Pfister, Frederick; Wang, Yumei; Schreiter, Kay; vom Hagen, Franziska; Altvater, Karin; Hoffmann, Sigrid; Deutsch, Urban; Hammes, Hans-Peter; Feng, Yuxi (2010). Retinal overexpression of angiopoietin-2 mimics diabetic retinopathy and enhances vascular damages in hyperglycemia. Acta diabetologica, 47(1), pp. 59-64. Milano: Springer 10.1007/s00592-009-0099-2

Shcherbina, Anna; Cooley, Jessica; Lutskiy, Maxim I; Benarafa, Charaf; Gilbert, Gary E; Remold-O'Donnell, Eileen (2010). WASP plays a novel role in regulating platelet responses dependent on alphaIIbbeta3 integrin outside-in signalling. British journal of haematology, 148(3), pp. 416-27. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.2009.07959.x

Leopardi, Paola; Cordelli, Eugenia; Villani, Paola; Cremona, Tiziana Patrizia; Conti, Luigi; De Luca, Gabriele; Crebelli, Riccardo (2010). Assessment of in vivo genotoxicity of the rodent carcinogen furan: evaluation of DNA damage and induction of micronuclei in mouse splenocytes. Mutagenesis, 25(1), pp. 57-62. Oxford: Oxford University Press 10.1093/mutage/gep043

Kumar, Varsha; Scandella, Elke; Danuser, Renzo; Onder, Lucas; Nitschké, Maximilian; Fukui, Yoshinori; Halin, Cornelia; Ludewig, Burkhard; Stein, Jens V (2010). Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway. Blood, 115(23), pp. 4725-33. Washington, D.C.: American Society of Hematology 10.1182/blood-2009-10-250118

Boscacci, Rémy T; Pfeiffer, Friederike; Gollmer, Kathrin; Checa Sevilla, Ana Isabel; Martin, Ana Maria; Soriano, Silvia Fernandez; Natale, Daniela; Henrickson, Sarah; von Andrian, Ulrich H; Fukui, Yoshinori; Mellado, Mario; Deutsch, Urban; Engelhardt, Britta; Stein, Jens V (2010). Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing. Blood, 116(6), pp. 915-25. Washington, D.C.: American Society of Hematology 10.1182/blood-2009-11-254334

Simarro, Maria; Gimenez-Cassina, Alfredo; Kedersha, Nancy; Lazaro, Jean-Bernard; Adelmant, Guillaume O; Marto, Jarrod A; Rhee, Kirsten; Tisdale, Sarah; Danial, Nika; Benarafa, Charaf; Orduña, Anonio; Anderson, Paul (2010). Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration. Biochemical and biophysical research communications, 401(3), pp. 440-6. Orlando, Fla.: Academic Press 10.1016/j.bbrc.2010.09.075

Simarro, Maria; Giannattasio, Giorgio; De la Fuente, Miguel A; Benarafa, Charaf; Subramanian, Kulandayan K; Ishizawar, Rumey; Balestrieri, Barbara; Andersson, Emma M; Luo, Hongbo R; Orduña, Antonio; Boyce, Joshua; Anderson, Paul (2010). Fas-activated serine/threonine phosphoprotein promotes immune-mediated pulmonary inflammation. Journal of immunology, 184(9), pp. 5325-32. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1000104

Steiner, Oliver; Coisne, Caroline; Cecchelli, Roméo; Boscacci, Rémy; Deutsch, Urban; Engelhardt, Britta; Lyck, Ruth (2010). Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood-brain barrier endothelium. Journal of immunology, 185(8), pp. 4846-55. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0903732

Jain, Pooja; Coisne, Caroline; Enzmann, Gaby; Rottapel, Robert; Engelhardt, Britta (2010). Alpha4beta1 integrin mediates the recruitment of immature dendritic cells across the blood-brain barrier during experimental autoimmune encephalomyelitis. Journal of immunology, 184(12), pp. 7196-206. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0901404

Coisne, Caroline; Engelhardt, Britta (2010). Preclinical testing of strategies for therapeutic targeting of human T-cell trafficking in vivo. Methods in molecular biology, 616, pp. 268-281. Totowa, N.J.: Humana Press 10.1007/978-1-60761-461-6_17

Wang, Yingdi; Nakayama, Masanori; Pitulescu, Mara E; Schmidt, Tim S; Bochenek, Magdalena L; Sakakibara, Akira; Adams, Susanne; Davy, Alice; Deutsch, Urban; Lüthi, Urs; Barberis, Alcide; Benjamin, Laura E; Mäkinen, Taija; Nobes, Catherine D; Adams, Ralf H (2010). Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Nature, 465(7297), pp. 483-6. London: Macmillan Journals Ltd. 10.1038/nature09002

Lélu, Karine; Delpy, Laurent; Robert, Virginie; Foulon, Eliane; Laffont, Sophie; Pelletier, Lucette; Engelhardt, Britta; Guéry, Jean-Charles (2010). Endogenous estrogens, through estrogen receptor , constrain autoimmune inflammation in female mice by limiting CD4(+) T-cell homing into the CNS. European journal of immunology, 40(12), pp. 3489-3498. Weinheim: Wiley-VCH 10.1002/eji.201040678

Kirschner, Daniel A; Avila, Robin L; Gamez Sazo, Rodolfo E; Luoma, Adrienne; Enzmann, Gaby U; Agrawal, Deepika; Inouye, Hideyo; Bunge, Mary Bartlett; Kocsis, Jeffery; Peters, Alan; Whittemore, Scott R (2010). Rapid assessment of internodal myelin integrity in central nervous system tissue. Journal of neuroscience research, 88(4), pp. 712-21. New York, N.Y.: Wiley-Liss 10.1002/jnr.22241

Faroudi, Mustapha; Hons, Miroslav; Zachacz, Agnieszka; Dumont, Celine; Lyck, Ruth; Stein, Jens V; Tybulewicz, Victor L J (2010). Critical roles for Rac GTPases in T-cell migration to and within lymph nodes. Blood, 116(25), pp. 5536-47. Washington, D.C.: American Society of Hematology 10.1182/blood-2010-08-299438

Moalli, Federica; Doni, Andrea; Deban, Livija; Zelante, Teresa; Zagarella, Silvia; Bottazzi, Barbara; Romani, Luigina; Mantovani, Alberto; Garlanda, Cecilia (2010). Role of complement and Fc{gamma} receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus. Blood, 116(24), pp. 5170-80. Washington, D.C.: American Society of Hematology 10.1182/blood-2009-12-258376

Deban, Livija; Russo, Remo Castro; Sironi, Marina; Moalli, Federica; Scanziani, Margherita; Zambelli, Vanessa; Cuccovillo, Ivan; Bastone, Antonio; Gobbi, Marco; Valentino, Sonia; Doni, Andrea; Garlanda, Cecilia; Danese, Silvio; Salvatori, Giovanni; Sassano, Marica; Evangelista, Virgilio; Rossi, Barbara; Zenaro, Elena; Constantin, Gabriela; Laudanna, Carlo; ... (2010). Regulation of leukocyte recruitment by the long pentraxin PTX3. Nature immunology, 11(4), pp. 328-34. New York, N.Y.: Nature Publishing Group 10.1038/ni.1854

Engelhardt, B.2010 (2010). T cell migration into the CNS during health and disease: Different molecular keys allow access to different CNS compartments. Clinical and experimental neuroimmunology Oxford: Wiley-Blackwell

Engelhardt, Britta (2010). Negotiating the brain barriers: Access of immune cells and pathogens into the CNS. In: Kilpatrick, Trevor; Ransohoff, Richard M; Wesselingh, Steven (eds.) Inflammatory Diseases of the Central Nervous System (pp. 35-46). Cambridge: Cambridge University Press

Clemetson, Kenneth John (2010). Platelets and pathogens. Cellular and molecular life sciences, 67(4), pp. 495-498. SP Birkhäuser Verlag Basel 10.1007/s00018-009-0204-2

Schwarz, Edward M; Proulx, Steven T; Ritchlin, Christopher T; Boyce, Brendan F; Xing, Lianping (2010). The role of bone marrow edema and lymphangiogenesis in inflammatory-erosive arthritis. Advances in experimental medicine and biology, 658, pp. 1-10. Springer 10.1007/978-1-4419-1050-9_1

2009

Guo, Ruolin; Zhou, Quan; Proulx, Steven T; Wood, Ronald; Ji, Rui-Cheng; Ritchlin, Christopher T; Pytowski, Bronislaw; Zhu, Zhenping; Wang, Yong-Jun; Schwarz, Edward M; Xing, Lianping (2009). Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis. Arthritis & rheumatism, 60(9), pp. 2666-2676. Wiley-Blackwell 10.1002/art.24764

Ritchlin, Christopher T; Proulx, Steven T; Schwarz, Edward S (2009). Translational perspectives on psoriatic arthritis. The journal of rheumatology. Supplement, 83, pp. 30-34. The Journal of Rheumatology Publishing Company Limited 10.3899/jrheum.090219

Buonomano, Roberto; Brinkmann, Franziska; Leupin, Nicolas; Boscacci, R; Zimmermann, Arthur; Muller, Norbert; Fux, Christoph (2009). Holiday souvenirs from the Mediterranean: three instructive cases of visceral leishmaniasis. Scandinavian journal of infectious diseases, 41(10), pp. 777-81. Oslo: Informa Healthcare 10.1080/00365540903104127

Rossy, Jérémie; Schlicht, Dominique; Engelhardt, Britta; Niggli, Verena (2009). Flotillins interact with PSGL-1 in neutrophils and, upon stimulation, rapidly organize into membrane domains subsequently accumulating in the uropod. PLoS ONE, 4(4), e5403. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0005403

Maerki, Christa; Meuter, Simone; Liebi, Mark; Mühlemann, Kathrin; Frederick, Mitchell J; Yawalkar, Nikhil; Moser, Bernhard; Wolf, Marlene (2009). Potent and broad-spectrum antimicrobial activity of CXCL14 suggests an immediate role in skin infections. Journal of immunology, 182(1), pp. 507-14. Bethesda, Md.: American Association of Immunologists

Engelhardt, Britta (2009). PSGL-1--the hidden player in T cell trafficking into the brain in multiple sclerosis? Journal of leukocyte biology, 86(5), pp. 1023-5. Bethesda, Md.: Society for Leukocyte Biology 10.1189/jlb.0509358

Engelhardt, Britta; Sorokin, Lydia (2009). The blood-brain and the blood-cerebrospinal fluid barriers: function and dysfunction. Seminars in immunopathology, 31(4), pp. 497-511. Berlin: Springer-Verlag 10.1007/s00281-009-0177-0

Wolburg-Buchholz, Karen; Mack, Andreas F; Steiner, Esther; Pfeiffer, Friederike; Engelhardt, Britta; Wolburg, Hartwig (2009). Loss of astrocyte polarity marks blood-brain barrier impairment during experimental autoimmune encephalomyelitis. Acta neuropathologica, 118(2), pp. 219-33. Berlin: Springer 10.1007/s00401-009-0558-4

Lyck, Ruth; Ruderisch, Nadine; Moll, Anton G; Steiner, Oliver; Cohen, Clemens D; Engelhardt, Britta; Makrides, Victoria; Verrey, Francois (2009). Culture-induced changes in blood-brain barrier transcriptome: implications for amino-acid transporters in vivo. Journal of cerebral blood flow and metabolism, 29(9), pp. 1491-502. New York, N.Y.: Nature Publishing Group 10.1038/jcbfm.2009.72

Dodelet-Devillers, Aurore; Cayrol, Romain; van Horssen, Jack; Haqqani, Arsalan S; de Vries, Helga E; Engelhardt, Britta; Greenwood, John; Prat, Alexandre (2009). Functions of lipid raft membrane microdomains at the blood-brain barrier. Journal of molecular medicine JMM, 87(8), pp. 765-74. Berlin: Springer 10.1007/s00109-009-0488-6

Coisne, Caroline; Mao, Wenxian; Engelhardt, Britta (2009). Cutting edge: Natalizumab blocks adhesion but not initial contact of human T cells to the blood-brain barrier in vivo in an animal model of multiple sclerosis. Journal of immunology, 182(10), pp. 5909-13. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803418

Reboldi, Andrea; Coisne, Caroline; Baumjohann, Dirk; Benvenuto, Federica; Bottinelli, Denise; Lira, Sergio; Uccelli, Antonio; Lanzavecchia, Antonio; Engelhardt, Britta; Sallusto, Federica (2009). C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nature immunology, 10(5), pp. 514-23. New York, N.Y.: Nature Publishing Group 10.1038/ni.1716

Woodfin, Abigail; Voisin, Mathieu-Benoit; Imhof, Beat A; Dejana, Elisabetta; Engelhardt, Britta; Nourshargh, Sussan (2009). Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1. Blood, 113(24), pp. 6246-57. Washington, D.C.: American Society of Hematology 10.1182/blood-2008-11188375

Bauer, Martina; Brakebusch, Cord; Coisne, Caroline; Sixt, Michael; Wekerle, Hartmut; Engelhardt, Britta; Fässler, Reinhard (2009). Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 106(6), pp. 1920-5. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.0808909106

Baig, Akeel; Bao, Xiankun; Wolf, Marlene; Haslam, Richard J (2009). The platelet protein kinase C substrate pleckstrin binds directly to SDPR protein. Platelets, 20(7), pp. 446-457. London: Informa Healthcare 10.3109/09537100903137314

Feng, Yuxi; Vom Hagen, Franziska; Wang, Yumei; Beck, Susanne; Schreiter, Kay; Pfister, Frederick; Hoffmann, Sigrid; Wagner, Patrick; Seeliger, Mathias; Molema, Grietje; Deutsch, Urban; Hammes, Hans-Peter (2009). The absence of angiopoietin-2 leads to abnormal vascular maturation and persistent proliferative retinopathy. Thrombosis and haemostasis, 102(1), pp. 120-30. Stuttgart: Schattauer 10.1160/TH08-09-0567

Feng, Yuxi; Wang, Yumei; Pfister, Frederick; Hillebrands, Jan-Luuk; Deutsch, Urban; Hammes, Hans-Peter (2009). Decreased hypoxia-induced neovascularization in angiopoietin-2 heterozygous knockout mouse through reduced MMP activity. Cellular physiology and biochemistry, 23(4-6), pp. 277-84. Basel: Karger 10.1159/000218174

Winderlich, Mark; Keller, Linda; Cagna, Giuseppe; Broermann, Andre; Kamenyeva, Olena; Kiefer, Friedemann; Deutsch, Urban; Nottebaum, Astrid F; Vestweber, Dietmar (2009). VE-PTP controls blood vessel development by balancing Tie-2 activity. Journal of cell biology, 185(4), pp. 657-71. New York, N.Y.: Rockefeller Institute Press 10.1083/jcb.200811159

Noell, Susan; Fallier-Becker, Petra; Deutsch, Urban; Mack, Andreas F; Wolburg, Hartwig (2009). Agrin defines polarized distribution of orthogonal arrays of particles in astrocytes. Cell and tissue research, 337(2), pp. 185-95. Heidelberg: Springer 10.1007/s00441-009-0812-z

Kokai, Enikö; Voss, Florian; Fleischer, Frank; Kempe, Sybille; Marinkovic, Dragan; Wolburg, Hartwig; Leithäuser, Frank; Schmidt, Volker; Deutsch, Urban; Wirth, Thomas (2009). Myc regulates embryonic vascular permeability and remodeling. Circulation research, 104(10), pp. 1151-9. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.108.191460

Reiss, Yvonne; Knedla, Anette; Tal, Andrea O; Schmidt, Mirko H H; Jugold, Manfred; Kiessling, Fabian; Burger, Angelika M; Wolburg, Hartwig; Deutsch, Urban; Plate, Karl H (2009). Switching of vascular phenotypes within a murine breast cancer model induced by angiopoietin-2. Journal of pathology, 217(4), pp. 571-80. Chichester: Wiley 10.1002/path.2484

Stein, Jens Volker (2009). Close encounters of the 3D kind. Blood, 113(23), pp. 5698-5699. Washington, D.C.: American Society of Hematology 10.1182/blood-2009-03-208538

Gollmer, Kathrin; Asperti-Boursin, François; Tanaka, Yoshihiko; Okkenhaug, Klaus; Vanhaesebroeck, Bart; Peterson, Jeffrey R; Fukui, Yoshinori; Donnadieu, Emmanuel; Stein, Jens V (2009). CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway. Blood, 114(3), pp. 580-8. Washington, D.C.: American Society of Hematology 10.1182/blood-2009-01-200923

Stein, Jens Volker (2009). How to be naive. Immunity, 31(1), pp. 9-11. Cambridge, Mass.: Cell Press 10.1016/j.immuni.2009.06.010

Beare, Jason E; Morehouse, Johnny R; DeVries, William H; Enzmann, Gaby U; Burke, Darlene A; Magnuson, David S K; Whittemore, Scott R (2009). Gait analysis in normal and spinal contused mice using the TreadScan system. Journal of neurotrauma, 26(11), pp. 2045-56. New York, N.Y.: M.A. Liebert 10.1089/neu.2009.0914

Magnuson, David S K; Smith, Rebecca R; Brown, Edward H; Enzmann, Gaby; Angeli, Claudia; Quesada, Peter M; Burke, Darlene (2009). Swimming as a model of task-specific locomotor retraining after spinal cord injury in the rat. Neurorehabilitation and neural repair, 23(6), pp. 535-45. Thousand Oaks, Calif.: Sage Publications 10.1177/1545968308331147

Baumgartner, Stephan; Wolf, Martin; Skrabal, Peter; Bangerter, Felix; Heusser, Peter; Thurneysen, André; Wolf, Ursula (2009). High-field 1H T1 and T2 NMR Relaxation Time Measurements of H2O in Homeopathic Preparations of Quartz, Sulfur and Copper Sulfate. Naturwissenschaften, 96(9), pp. 1079-1089. New York, N.Y.: Springer-Verlag 10.1007/s00114-009-0569-y

2008

Tsutsumi, Ryosuke; Hock, Colleen; Bechtold, C Dustin; Proulx, Steven T; Bukata, Susan V; Ito, Hiromu; Awad, Hani A; Nakamura, Takashi; O'Keefe, Regis J; Schwarz, Edward M (2008). Differential effects of biologic versus bisphosphonate inhibition of wear debris-induced osteolysis assessed by longitudinal micro-CT. Journal of orthopaedic research, 26(10), pp. 1340-1346. Wiley 10.1002/jor.20620

Proulx, Steven T; Kwok, Edmund; You, Zhigang; Papuga, M Owen; Beck, Christopher A; Shealy, David J; Calvi, Laura M; Ritchlin, Christopher T; Awad, Hani A; Boyce, Brendan F; Xing, Lianping; Schwarz, Edward M (2008). Elucidating bone marrow edema and myelopoiesis in murine arthritis using contrast-enhanced magnetic resonance imaging. Arthritis & rheumatism, 58(7), pp. 2019-2029. Wiley-Blackwell 10.1002/art.23546

Dufourcq, Pascale; Leroux, Lionel; Ezan, Jérome; Descamps, Betty; Lamazière, Jean-Marie Daniel; Costet, Pierre; Basoni, Caroline; Moreau, Catherine; Deutsch, Urban; Couffinhal, Thierry; Duplàa, Cécile (2008). Regulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formation. American journal of pathology, 172(1), pp. 37-49. New York, N.Y.: Elsevier 10.2353/ajpath.2008.070130

Clemetson, Kenneth J; Clemetson, Jeannine M (2008). Platelet GPIb complex as a target for anti-thrombotic drug development. Thrombosis and haemostasis, 99(3), pp. 473-9. Stuttgart: Schattauer 10.1160/TH07-12-0718

Li, Rui; Zhu, Shaowen; Wu, Jianbo; Wang, Wanyu; Lu, Qiumin; Clemetson, Kenneth J (2008). L-amino acid oxidase from Naja atra venom activates and binds to human platelets. Acta biochimica et biophysica Sinica - ABBS, 40(1), pp. 19-26. Shanghai: Inst. of Biochemistry and Cell Biology 10.1111/j.1745-7270.2008.00372.x

Deutsch, Urban; Schlaeger, Thorsten M; Dehouck, Bénédicte; Döring, Axinia; Tauber, Silke; Risau, Werner; Engelhardt, Britta (2008). Inducible endothelial cell-specific gene expression in transgenic mouse embryos and adult mice. Experimental cell research, 314(6), pp. 1202-16. San Diego, Calif.: Elsevier 10.1016/j.yexcr.2007.12.026

Feng, Yuxi; Pfister, Frederick; Schreiter, Kay; Wang, Yumei; Stock, Oliver; Vom Hagen, Franziska; Wolburg, Hartwig; Hoffmann, Sigrid; Deutsch, Urban; Hammes, Hans-Peter (2008). Angiopoietin-2 deficiency decelerates age-dependent vascular changes in the mouse retina. Cellular physiology and biochemistry, 21(1-3), pp. 129-36. Basel: Karger 10.1159/000113755

Wolf, Marlene; Albrecht, Stefan; Märki, Christa (2008). Proteolytic processing of chemokines: implications in physiological and pathological conditions. International journal of biochemistry & cell biology, 40(6-7), pp. 1185-98. Amsterdam: Elsevier 10.1016/j.biocel.2007.12.009

Owens, Trevor; Bechmann, Ingo; Engelhardt, Britta (2008). Perivascular spaces and the two steps to neuroinflammation. Journal of neuropathology and experimental neurology, 67(12), pp. 1113-21. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/NEN.0b013e31818f9ca8

Nottebaum, Astrid F; Cagna, Giuseppe; Winderlich, Mark; Gamp, Alexander C; Linnepe, Ruth; Polaschegg, Christian; Filippova, Kristina; Lyck, Ruth; Engelhardt, Britta; Kamenyeva, Olena; Bixel, Maria Gabriele; Butz, Stefan; Vestweber, Dietmar (2008). VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF. Journal of experimental medicine, 205(12), pp. 2929-45. New York, N.Y.: Rockefeller University Press 10.1084/jem.20080406

Linker, Ralf A; Lühder, Fred; Kallen, Karl-Josef; Lee, De-Hyung; Engelhardt, Britta; Rose-John, Stefan; Gold, Ralf (2008). IL-6 transsignalling modulates the early effector phase of EAE and targets the blood-brain barrier. Journal of neuroimmunology, 205(1-2), pp. 64-72. Amsterdam: Elsevier 10.1016/j.jneuroim.2008.09.007

Schrage, Arnhild; Wechsung, Katja; Neumann, Katrin; Schumann, Michael; Schulzke, Jörg-Dieter; Engelhardt, Britta; Zeitz, Martin; Hamann, Alf; Klugewitz, Katja (2008). Enhanced T cell transmigration across the murine liver sinusoidal endothelium is mediated by transcytosis and surface presentation of chemokines. Hepatology, 48(4), pp. 1262-72. Hoboken, N.J.: Wiley Interscience 10.1002/hep.22443

Engelhardt, Britta (2008). The blood-central nervous system barriers actively control immune cell entry into the central nervous system. Current pharmaceutical design, 14(16), pp. 1555-65. Hilversum: Bentham Science Publishers 10.2174/138161208784705432

Uboldi, Chiara; Döring, Axinia; Alt, Carsten; Estess, Pila; Siegelman, Mark; Engelhardt, Britta (2008). L-Selectin-deficient SJL and C57BL/6 mice are not resistant to experimental autoimmune encephalomyelitis. European journal of immunology, 38(8), pp. 2156-67. Weinheim: Wiley-VCH 10.1002/eji.200838209

Pfeiffer, Friederike; Kumar, Varsha; Butz, Stefan; Vestweber, Dietmar; Imhof, Beat A; Stein, Jens V; Engelhardt, Britta (2008). Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node. European journal of immunology, 38(8), pp. 2142-55. Weinheim: Wiley-VCH 10.1002/eji.200838140

Engelhardt, Britta (2008). Immune cell entry into the central nervous system: involvement of adhesion molecules and chemokines. Journal of the neurological sciences, 274(1-2), pp. 23-6. Amsterdam: Elsevier 10.1016/j.jns.2008.05.019

Sellner, Johann; Greeve, Isabell; Findling, Oliver; Kamm, Christian P.; Minten, Carsten; Engelhardt, Britta; Grandgirard, Denis; Leib, Stephen L.; Mattle, Heinrich P (2008). Effect of interferon-beta and atorvastatin on Th1/Th2 cytokines in multiple sclerosis. Neurochemistry international, 53(1-2), pp. 17-21. Amsterdam: Elsevier 10.1016/j.neuint.2008.04.004

Kraus, J; Voigt, K; Schuller, A M; Scholz, M; Kim, K S; Schilling, M; Schäbitz, W R; Oschmann, P; Engelhardt, B (2008). Interferon-beta stabilizes barrier characteristics of the blood-brain barrier in four different species in vitro. Multiple sclerosis journal, 14(6), pp. 843-52. London: Sage 10.1177/1352458508088940

Endres, Matthias; Engelhardt, Britta; Koistinaho, Jari; Lindvall, Olle; Meairs, Stephen; Mohr, Jay P; Planas, Anna; Rothwell, Nancy; Schwaninger, Markus; Schwab, Martin E; Vivien, Denis; Wieloch, Tadeusz; Dirnagl, Ulrich (2008). Improving outcome after stroke: overcoming the translational roadblock. Cerebrovascular diseases, 25(3), pp. 268-78. Basel: Karger 10.1159/000118039

Neuwelt, Edward; Abbott, N Joan; Abrey, Lauren; Banks, William A; Blakley, Brian; Davis, Thomas; Engelhardt, Britta; Grammas, Paula; Nedergaard, Maiken; Nutt, John; Pardridge, William; Rosenberg, Gary A; Smith, Quentin; Drewes, Lester R (2008). Strategies to advance translational research into brain barriers. Lancet neurology, 7(1), pp. 84-96. Oxford: Elsevier 10.1016/S1474-4422(07)70326-5

Engelhardt, Britta; Kappos, Ludwig (2008). Natalizumab: targeting alpha4-integrins in multiple sclerosis. Neurodegenerative diseases, 5(1), pp. 16-22. Basel: Karger 10.1159/000109933

Swendeman, Steven; Mendelson, Karen; Weskamp, Gisela; Horiuchi, Keisuke; Deutsch, Urban; Scherle, Peggy; Hooper, Andrea; Rafii, Shahin; Blobel, Carl P (2008). VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling. Circulation research, 103(9), pp. 916-8. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.108.184416

Leen, Laetitia Lam Shang; Filipe, Cédric; Billon, Audrey; Garmy-Susini, Barbara; Jalvy, Sandra; Robbesyn, Fanny; Daret, Danièle; Allières, Cécile; Rittling, Susan R; Werner, Nikos; Nickenig, Georg; Deutsch, Urban; Duplàa, Cécile; Dufourcq, Pascale; Lenfant, Françoise; Desgranges, Claude; Arnal, Jean-François; Gadeau, Alain-Pierre (2008). Estrogen-stimulated endothelial repair requires osteopontin. Arteriosclerosis, thrombosis, and vascular biology, 28(12), pp. 2131-6. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1161/ATVBAHA.108.167965

Pfister, Frederick; Feng, Yuxi; vom Hagen, Franziska; Hoffmann, Sigrid; Molema, Grietje; Hillebrands, Jan-Luuk; Shani, Moshe; Deutsch, Urban; Hammes, Hans-Peter (2008). Pericyte migration: a novel mechanism of pericyte loss in experimental diabetic retinopathy. Diabetes, 57(9), pp. 2495-502. Alexandria, Va.: American Diabetes Association 10.2337/db08-0325

Saharinen, Pipsa; Eklund, Lauri; Miettinen, Juho; Wirkkala, Riikka; Anisimov, Andrey; Winderlich, Mark; Nottebaum, Astrid; Vestweber, Dietmar; Deutsch, Urban; Koh, Gou Young; Olsen, Bjorn R; Alitalo, Kari (2008). Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. Nature cell biology, 10(5), pp. 527-37. London: Nature Publishing Group 10.1038/ncb1715

Hooley, Elizabeth; Papagrigoriou, Evangelos; Navdaev, Alexei; Pandey, Amit V; Clemetson, Jeannine M; Clemetson, Kenneth J; Emsley, Jonas (2008). The crystal structure of the platelet activator aggretin reveals a novel (alphabeta)2 dimeric structure. Biochemistry, 47(30), pp. 7831-7837. Washington, D.C.: American Chemical Society 10.1021/bi800528t

Mira, Emilia; León, Beatriz; Barber, Domingo F; Jiménez-Baranda, Sonia; Goya, Iñigo; Almonacid, Luis; Márquez, Gabriel; Zaballos, Angel; Martínez-A, Carlos; Stein, Jens V; Ardavín, Carlos; Mañes, Santos (2008). Statins induce regulatory T cell recruitment via a CCL1 dependent pathway. Journal of immunology, 181(5), pp. 3524-34. Bethesda, Md.: American Association of Immunologists

Thelen, Marcus; Stein, Jens V (2008). How chemokines invite leukocytes to dance. Nature immunology, 9(9), pp. 953-9. New York, N.Y.: Nature Publishing Group 10.1038/ni.f.207

Engelhardt, B. (2008). Adhesion and signalling molecules controlling the extravasation of leukocytes accross the endothelium. Transfusion medicine and hemotherapy, 35(2), pp. 73-75. Basel: Karger 10.1159/000119115

Goerge, Tobias; Ho-Tin-Noe, Benoit; Carbo, Carla; Benarafa, Charaf; Remold-O'Donnell, Eileen; Zhao, Bing-Qiao; Cifuni, Stephen M; Wagner, Denisa D (2008). Inflammation induces hemorrhage in thrombocytopenia. Blood, 111(10), pp. 4958-64. Washington, D.C.: American Society of Hematology 10.1182/blood-2007-11-123620

2007

Proulx, Steven T; Kwok, Edmund; You, Zhigang; Papuga, M Owen; Beck, Christopher A; Shealy, David J; Ritchlin, Christopher T; Awad, Hani A; Boyce, Brendan F; Xing, Lianping; Schwarz, Edward M (2007). Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice by in vivo magnetic resonance imaging and microfocal computed tomography. Arthritis & rheumatism, 56(12), pp. 4024-4037. Wiley-Blackwell 10.1002/art.23128

Proulx, Steven T; Kwok, Edmund; You, Zhigang; Beck, Christopher A; Shealy, David J; Ritchlin, Christopher T; Boyce, Brendan F; Xing, Lianping; Schwarz, Edward M (2007). MRI and quantification of draining lymph node function in inflammatory arthritis. Annals of the New York Academy of Sciences, 1117(1), pp. 106-123. Wiley 10.1196/annals.1402.016

Clemetson, Kenneth John; Clemetson, Jeannine (2007). Platelet Receptors. In: Michelson, Alan D (ed.) Platelets, Second Edition (pp. 117-144). Fribourg: Elsevier

Clemetson, Kenneth J (2007). A short history of platelet glycoprotein Ib complex. Thrombosis and haemostasis, 98(1), pp. 63-8. Stuttgart: Schattauer 10.1160/TH07-05-0327

Thiele, Thomas; Steil, Leif; Gebhard, Simon; Scharf, Christian; Hammer, Elke; Brigulla, Matthias; Lubenow, Norbert; Clemetson, Kenneth J; Völker, Uwe; Greinacher, Andreas (2007). Profiling of alterations in platelet proteins during storage of platelet concentrates. Transfusion, 47(7), pp. 1221-33. Malden, Mass.: Wiley-Blackwell 10.1111/j.1537-2995.2007.01255.x

Clemetson, Kenneth J (2007). American Society of Hematology--48th Annual Meeting and Exposition. Updates on therapies. 9-12 December 2006 Orlando, FL, USA. IDrugs, 10(2), pp. 90-2. London: Thomson Scientific

Clemetson, Kenneth J; Lu, Qiumin; Clemetson, Jeannine M (2007). Snake venom proteins affecting platelets and their applications to anti-thrombotic research. Current pharmaceutical design, 13(28), pp. 2887-92. Hilversum: Bentham Science Publishers 10.2174/138161207782023702

Clemetson, Kenneth J; Clemetson, Jeannine M (2007). Collagen receptors as potential targets for novel anti-platelet agents. Current pharmaceutical design, 13(26), pp. 2673-83. Hilversum: Bentham Science Publishers 10.2174/138161207781662894

Döring, Axinia; Wild, Martin; Vestweber, Dietmar; Deutsch, Urban; Engelhardt, Britta (2007). E- and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice. Journal of immunology, 179(12), pp. 8470-9. Bethesda, Md.: American Association of Immunologists

Yuan, Hai Tao; Venkatesha, Shivalingappa; Chan, Barden; Deutsch, Urban; Mammoto, Tadanori; Sukhatme, Vikas P; Woolf, Adrian S; Karumanchi, S Ananth (2007). Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival. FASEB journal, 21(12), pp. 3171-83. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.07-8487com

Feng, Yuxi; vom Hagen, Franziska; Pfister, Frederick; Djokic, Snezana; Hoffmann, Sigrid; Back, Walter; Wagner, Patrick; Lin, Jihong; Deutsch, Urban; Hammes, Hans-Peter (2007). Impaired pericyte recruitment and abnormal retinal angiogenesis as a result of angiopoietin-2 overexpression. Thrombosis and haemostasis, 97(1), pp. 99-108. Stuttgart: Schattauer 10.1160/TH06-05-0277

Jagasia, Madan; Giglia, Jennifer; Chinratanalab, Wichai; Dixon, Sheri; Chen, Heidi; Frangoul, Haydar; Engelhardt, Brian; Goodman, Stacey; Greer, John; Kassim, Adetola; Morgan, David; Ruffner, Katherine; Schuening, Friedrich (2007). Incidence and outcome of chronic graft-versus-host disease using National Institutes of Health consensus criteria. Biology of blood and marrow transplantation, 13(10), pp. 1207-15. New York, N.Y.: Elsevier 10.1016/j.bbmt.2007.07.001

Engelhardt, Brian G; Holland, Derek W; Brandt, Stephen J; Chinratanalab, Wichai; Goodman, Stacey A; Greer, John P; Jagasia, Madan H; Kassim, Adetola A; Morgan, David S; Ruffner, Katherine L; Schuening, Friedrich G; Wolff, Steven; Bitting, Rhonda; Sulur, Paulgun; Stein, Richard S (2007). High-dose chemotherapy followed by autologous stem cell transplantation for relapsed or refractory Hodgkin lymphoma: prognostic features and outcomes. Leukemia & lymphoma, 48(9), pp. 1728-35. London: Informa Healthcare 10.1080/10428190701534374

Klotz, Luisa; Diehl, Linda; Dani, Indra; Neumann, Harald; von Oppen, Nanette; Dolf, Andreas; Endl, Elmar; Klockgether, Thomas; Engelhardt, Britta; Knolle, Percy (2007). Brain endothelial PPARgamma controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro. Journal of neuroimmunology, 190(1-2), pp. 34-43. Amsterdam: Elsevier 10.1016/j.jneuroim.2007.07.017

Coisne, Caroline; Lyck, Ruth; Engelhardt, Britta (2007). Therapeutic targeting of leukocyte trafficking across the blood-brain barrier. Inflammation & allergy, drug targets, 6(4), pp. 210-22. Sharjah: Bentham Science Publishers

Guarda, Greta; Hons, Miroslav; Soriano, Silvia F; Huang, Alex Y; Polley, Rosalind; Martín-Fontecha, Alfonso; Stein, Jens V; Germain, Ronald N; Lanzavecchia, Antonio; Sallusto, Federica (2007). L-selectin-negative CCR7- effector and memory CD8+ T cells enter reactive lymph nodes and kill dendritic cells. Nature immunology, 8(7), pp. 743-52. New York, N.Y.: Nature Publishing Group 10.1038/ni1469

Nombela-Arrieta, César; Mempel, Thorsten R; Soriano, Silvia F; Mazo, Irina; Wymann, Matthias P; Hirsch, Emilio; Martínez-A, Carlos; Fukui, Yoshinori; von Andrian, Ulrich H; Stein, Jens V (2007). A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress. Journal of experimental medicine, 204(3), pp. 497-510. New York, N.Y.: Rockefeller University Press 10.1084/jem.20061780

Zhang, Qian; Lu, Yan; Proulx, Steven T; Guo, Ruolin; Yao, Zhenqiang; Schwarz, Edward M; Boyce, Brendan F; Xing, Lianping (2007). Increased lymphangiogenesis in joints of mice with inflammatory arthritis. Arthritis research & therapy, 9(6), R118. BioMed Central 10.1186/ar2326

2006

Engelhardt, Britta (2006). Immune cell migration across the blood–brain barrier: molecular mechanisms and therapeutic targeting. Future neurology, 1(1), 47 - 56. London: Future Medicine Ltd 10.2217/14796708.1.1.47

Bäumer, Sebastian; Keller, Linda; Holtmann, Astrid; Funke, Ruth; August, Benjamin; Gamp, Alexander; Wolburg, Hartwig; Wolburg-Buchholz, Karen; Deutsch, Urban; Vestweber, Dietmar (2006). Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development. Blood, 107(12), pp. 4754-62. Washington, D.C.: American Society of Hematology 10.1182/blood-2006-01-0141

Engelhardt, Britta (2006). Regulation of immune cell entry into the central nervous system. Results and problems in cell differentiation, 43, pp. 259-280. Berlin: Springer

Wethmar, Klaus; Helmus, Yvonne; Lühn, Kerstin; Jones, Claire; Laskowska, Anna; Varga, Georg; Grabbe, Stephan; Lyck, Ruth; Engelhardt, Britta; Bixel, M Gabriele; Butz, Stefan; Loser, Karin; Beissert, Stefan; Ipe, Ute; Vestweber, Dietmar; Wild, Martin K (2006). Migration of immature mouse DC across resting endothelium is mediated by ICAM-2 but independent of beta2-integrins and murine DC-SIGN homologues. European journal of immunology, 36(10), pp. 2781-94. Weinheim: Wiley-VCH 10.1002/eji.200526311

Hochmeister, Sonja; Grundtner, Roland; Bauer, Jan; Engelhardt, Britta; Lyck, Ruth; Gordon, Grace; Korosec, Thomas; Kutzelnigg, Alexandra; Berger, Johannes J; Bradl, Monika; Bittner, Reginald E; Lassmann, Hans (2006). Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis. Journal of neuropathology and experimental neurology, 65(9), pp. 855-65. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.jnen.0000235119.52311.16

Meairs, Stephen; Wahlgren, Nils; Dirnagl, Ulrich; Lindvall, Olle; Rothwell, Peter; Baron, Jean-Claude; Hossmann, Konstantin; Engelhardt, Britta; Ferro, José; McCulloch, James; Kaste, Markku; Endres, Matthias; Koistinaho, Jari; Planas, Anna; Vivien, Denis; Dijkhuizen, Rick; Czlonkowska, Anna; Hagen, Arne; Evans, Alan; De Libero, Gennaro; ... (2006). Stroke research priorities for the next decade--A representative view of the European scientific community. Cerebrovascular diseases, 22(2-3), pp. 75-82. Basel: Karger 10.1159/000093098

Engelhardt, B (2006). Molecular mechanisms involved in T cell migration across the blood-brain barrier. Journal of neural transmission, 113(4), pp. 477-85. Wien: Springer 10.1007/s00702-005-0409-y

Walter, Silke; Doering, Axinia; Letiembre, Maryse; Liu, Yang; Hao, Wenlin; Diem, Ricarda; Bernreuther, Christian; Glatzel, Markus; Engelhardt, Britta; Fassbender, Klaus (2006). The LPS receptor, CD14, in experimental autoimmune encephalomyelitis and multiple sclerosis. Cellular physiology and biochemistry, 17(3-4), pp. 167-72. Basel: Karger 10.1159/000092078

García-Bernal, David; Sotillo-Mallo, Elena; Nombela-Arrieta, César; Samaniego, Rafael; Fukui, Yoshinori; Stein, Jens V; Teixidó, Joaquin (2006). DOCK2 is required for chemokine-promoted human T lymphocyte adhesion under shear stress mediated by the integrin alpha4beta1. Journal of immunology, 177(8), pp. 5215-25. Bethesda, Md.: American Association of Immunologists

Pello, Oscar M; Duthey, Béatrice; García-Bernal, David; Rodríguez-Frade, José Miguel; Stein, Jens V; Teixido, Joaquín; Martínez, Carlos; Mellado, Mario (2006). Opioids trigger alpha 5 beta 1 integrin-mediated monocyte adhesion. Journal of immunology, 176(3), pp. 1675-85. Bethesda, Md.: American Association of Immunologists

Hasan, Lara; Mazzucchelli, Luca; Liebi, Mark; Lis, Maddalena; Hunger, Robert E; Tester, Angus; Overall, Christopher M; Wolf, Marlene (2006). Function of liver activation-regulated chemokine/CC chemokine ligand 20 is differently affected by cathepsin B and cathepsin D processing. Journal of immunology, 176(11), pp. 6512-22. Bethesda, Md.: American Association of Immunologists

Engelhardt, Britta (2006). Development of the Blood-Brain Interface. In: Dermietzel, Rolf; Spray, David C; Nedergaard, Maiken (eds.) Blood-Brain Barriers: From Ontogeny to Artificial Interfaces, Volume 1 (pp. 9-39). Weinheim: Wiley-VCH 10.1002/9783527611225.ch1

Engelhardt, Britta (2006). Physiologie der Blut-Hirn-Schranke – Bedeutung für die Neuroimmunmodulation. In: Straub, Rainer H (ed.) Lehrbuch der klinischen Pathophysiologie komplexer chronischer Erkrankungen. Band 1 (pp. 150-159). Göttingen: Vandenhoeck & Ruprecht V&R unipress

Clemetson, Kenneth John; Lu, Qiumin; Clemetson, Jeannine (2006). Snake C-type lectin-like proteins and platelet receptors. Pathophysiology of haemostasis and thrombosis, 34(4-5), pp. 150-155. Karger 10.1159/000092414

2005

Solum, NO; Clemetson, KJ (2005). The discovery and characterization of platelet GPIb. Journal of thrombosis and haemostasis, 3(6), pp. 1125-32. Oxford: Blackwell 10.1111/j.1538-7836.2005.01072.x

Alberio, L; Clemetson, KJ (2005). [Platelet inhibition and activation. Mechanisms and clinical implications.]. Herz, 30(3), pp. 176-80. München: Urban & Vogel 10.1007/s00059-005-2681-x

Bettex-Galland, M; Clemetson, KJ (2005). First isolation of actomyosin from a non-muscle cell: first isolated platelet protein. Journal of thrombosis and haemostasis, 3(5), pp. 834-9. Oxford: Blackwell 10.1111/j.1538-7836.2005.01261.x

Stephens, G; Yan, Y; Jandrot-Perrus, M; Villeval, JL; Clemetson, KJ; Phillips, DR (2005). Platelet activation induces metalloproteinase-dependent GP VI cleavage to down-regulate platelet reactivity to collagen. Blood, 105(1), pp. 186-91. Washington, D.C.: American Society of Hematology 10.1182/blood-2004-07-2842

Liang, HP; Morel-Kopp, MC; Clemetson, JM; Clemetson, KJ; Kekomaki, R; Kroll, H; Michaelides, K; Tuddenham, EG; Vanhoorelbeke, K; Ward, CM (2005). A common ancestral glycoprotein (GP) 9 1828A>G (Asn45Ser) gene mutation occurring in European families from Australia and Northern Europe with Bernard-Soulier Syndrome (BSS). Thrombosis and haemostasis, 94(3), pp. 599-605. Stuttgart: Schattauer 10.1160/TH05-03-0165

Lu, Q; Clemetson, JM; Clemetson, KJ (2005). Translocation of GPIb and Fc receptor gamma-chain to cytoskeleton in mucetin-activated platelets. Journal of thrombosis and haemostasis, 3(9), pp. 2065-76. Oxford: Blackwell 10.1111/j.1538-7836.2005.01481.x

Lu, Q; Clemetson, JM; Clemetson, KJ (2005). Snake venoms and hemostasis. Journal of thrombosis and haemostasis, 3(8), pp. 1791-9. Oxford: Blackwell 10.1111/j.1538-7836.2005.01358.x

Lu, Q; Navdaev, A; Clemetson, JM; Clemetson, KJ (2005). Snake venom C-type lectins interacting with platelet receptors. Structure-function relationships and effects on haemostasis. Toxicon, 45(8), pp. 1089-98. Oxford: Elsevier 10.1016/j.toxicon.2005.02.022

vom Hagen, F; Feng, Y; Hillenbrand, A; Hoffmann, S; Shani, M; Deutsch, U; Hammes, HP (2005). Early loss of arteriolar smooth muscle cells: more than just a pericyte loss in diabetic retinopathy. Experimental and clinical endocrinology & diabetes, 113(10), pp. 573-6. Stuttgart: Thieme 10.1055/s-2005-872894

Hoffmann, J; Feng, Y; vom Hagen, F; Hillenbrand, A; Lin, J; Erber, R; Vajkoczy, P; Gourzoulidou, E; Waldmann, H; Giannis, A; Wolburg, H; Shani, M; Jaeger, V; Weich, HA; Preissner, KT; Hoffmann, S; Deutsch, U; Hammes, HP (2005). Endothelial survival factors and spatial completion, but not pericyte coverage of retinal capillaries determine vessel plasticity. FASEB journal, 14(19), pp. 2035-6. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.04-2109fje

May, T; Mueller, PP; Weich, H; Froese, N; Deutsch, U; Wirth, D; Kröger, A; Hauser, H (2005). Establishment of murine cell lines by constitutive and conditional immortalization. Journal of biotechnology, 120(1), pp. 99-110. Amsterdam: Elsevier 10.1016/j.jbiotec.2005.03.027

2004

Alberio, LJ; Clemetson, KJ (2004). All platelets are not equal: COAT platelets. Current hematology reports, 3(5), pp. 338-43. Philadelphia, Pa.: Current Science

Clemetson, KJ; Clemetson, JM (2004). Platelet receptor signalling. Hematology journal, 3(5), S159-63. Basingstoke, UK: Nature Publishing Group 10.1038/sj.thj.6200444

Lu, Qiumin; Navdaev, Alexei; Clemetson, Jeannine; Clemetson, Kenneth John (2004). GPIb is involved in platelet aggregation induced by mucetin, a snake C-type lectin protein from Chinese habu (Trimeresurus mucrosquamatus) venom. Thrombosis and haemostasis, 91(6), pp. 1168-1176. Stuttgart: Schattauer 10.1160/TH03-12-0747

Ivkovic, S; Deutsch, U; Silberbach, A; Walraph, E; Mannel, M (2004). Dietary supplementation with the tribomechanically activated zeolite clinoptilolite in immunodeficiency: effects on the immune system. Advances in therapy, 21(2), pp. 135-147. Springer 10.1007/BF02850340

Deutsch, U (2004). Semaphorins guide PerPlexeD endothelial cells. Developmental cell, 7(1), pp. 1-2. Cambridge, Mass.: Cell Press 10.1016/j.devcel.2004.06.012

Hammes, HP; Lin, J; Wagner, P; Feng, Y; Vom Hagen, F; Krzizok, T; Renner, O; Breier, G; Brownlee, M; Deutsch, U (2004). Angiopoietin-2 causes pericyte dropout in the normal retina: evidence for involvement in diabetic retinopathy. Diabetes, 53(4), pp. 1104-10. Alexandria, Va.: American Diabetes Association 10.2337/diabetes.53.4.1104

Hamm, Stefan; Dehouck, Bénédicte; Kraus, Jörg; Wolburg-Buchholz, Karen; Wolburg, Hartwig; Risau, Werner; Cecchelli, Roméo; Engelhardt, Britta; Dehouck, Marie-Pierre (2004). Astrocyte mediated modulation of blood-brain barrier permeability does not correlate with a loss of tight junction proteins from the cellular contacts. Cell and tissue research, 315(2), pp. 157-166. Springer 10.1007/s00441-003-0825-y

2003

Lee, WH; Du, XY; Lu, QM; Clemetson, KJ; Zhang, Y (2003). Stejnulxin, a novel snake C-type lectin-like protein from Trimeresurus stejnegeri venom is a potent platelet agonist acting specifically via GPVI. Thrombosis and haemostasis, 90(4), pp. 662-71. Stuttgart: Schattauer 10.1160/TH03-05-0269

Chavakis, T; Santoso, S; Clemetson, KJ; Sachs, UJ; Isordia-Salas, I; Pixley, RA; Nawroth, PP; Colman, RW; Preissner, KT (2003). High molecular weight kininogen regulates platelet-leukocyte interactions by bridging Mac-1 and glycoprotein Ib. Journal of biological chemistry, 46(278), pp. 45375-81. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M304344200

Jurk, K; Clemetson, KJ; de Groot, PG; Brodde, MF; Steiner, M; Savion, N; Varon, D; Sixma, JJ; Van Aken, H; Kehrel, BE (2003). Thrombospondin-1 mediates platelet adhesion at high shear via glycoprotein Ib (GPIb): an alternative/backup mechanism to von Willebrand factor. FASEB journal, 11(17), pp. 1490-2. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.02-0830fje

Clemetson, KJ (2003). Platelet receptors and their role in diseases. Clinical chemistry and laboratory medicine, 3(41), pp. 253-260. Berlin: De Gruyter 10.1515/CCLM.2003.039

Fiedler, U; Krissl, T; Koidl, S; Weiss, C; Koblizek, T; Deutsch, U; Martiny-Baron, G; Marmé, D; Augustin, HG (2003). Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats. Journal of biological chemistry, 3(278), pp. 1721-7. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M208550200

2002

Alberio, L; Friese, P; Clemetson, KJ; Dale, GL (2002). Collagen response and glycoprotein VI function decline progressively as canine platelets age in vivo. Thrombosis and haemostasis, 88(3), pp. 510-6. Stuttgart: Schattauer

Navdaev, A; Clemetson, KJ (2002). Glycoprotein Ib cross-linking/ligation on echicetin-coated surfaces or echicetin-IgMkappa in stirred suspension activates platelets by cytoskeleton modulated calcium release. Journal of biological chemistry, 48(277), pp. 45928-34. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M206129200

Du, XY; Clemetson, KJ (2002). Snake venom L-amino acid oxidases. Toxicon, 40(6), pp. 659-65. Oxford: Elsevier 10.1016/S0041-0101(02)00102-2

Du, Xiao-Yan; Magnenat, E; Wells, TN; Clemetson, KJ (2002). Alboluxin, a snake C-type lectin from Trimeresurus albolabris venom is a potent platelet agonist acting via GPIb and GPVI. Thrombosis and haemostasis, 87(4), pp. 692-8. Stuttgart: Schattauer

Dale, GL; Friese, P; Batar, P; Hamilton, SF; Reed, GL; Jackson, KW; Clemetson, KJ; Alberio, L (2002). Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface. Nature, 6868(415), pp. 175-9. London: Macmillan Journals Ltd. 10.1038/415175a

Du, XY; Clemetson, JM; Navdaev, A; Magnenat, EM; Wells, TN; Clemetson, KJ (2002). Ophioluxin, a convulxin-like C-type lectin from Ophiophagus hannah (King cobra) is a powerful platelet activator via glycoprotein VI. Journal of biological chemistry, 38(277), pp. 35124-32. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M204372200

Uff, S; Clemetson, JM; Harrison, T; Clemetson, KJ; Emsley, J (2002). Crystal structure of the platelet glycoprotein Ib(alpha) N-terminal domain reveals an unmasking mechanism for receptor activation. Journal of biological chemistry, 38(277), pp. 35657-63. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M205271200

Hammes, HP; Lin, J; Renner, O; Shani, M; Lundqvist, A; Betsholtz, C; Brownlee, M; Deutsch, U (2002). Pericytes and the pathogenesis of diabetic retinopathy. Diabetes, 51(10), pp. 3107-12. Alexandria, Va.: American Diabetes Association 10.2337/diabetes.51.10.3107

Nawroth, R; Poell, G; Ranft, A; Kloep, S; Samulowitz, U; Fachinger, G; Golding, M; Shima, DT; Deutsch, U; Vestweber, D (2002). VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts. EMBO journal, 18(21), pp. 4885-95. London: Nature Publishing Group 10.1093/emboj/cdf497

Willecke, K; Eiberger, J; Degen, J; Eckardt, D; Romualdi, A; Güldenagel, M; Deutsch, U; Söhl, G (2002). Structural and functional diversity of connexin genes in the mouse and human genome. Biological chemistry, 5(383), pp. 725-737. Berlin: De Gruyter 10.1515/BC.2002.076

Palmer, A; Zimmer, M; Erdmann, KS; Eulenburg, V; Porthin, A; Heumann, R; Deutsch, U; Klein, R (2002). EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase. Molecular cell, 4(9), pp. 725-37. Cambridge, Mass.: Cell Press 10.1016/S1097-2765(02)00488-4

2001

Boehlen, F; Clemetson, KJ (2001). Platelet chemokines and their receptors: what is their relevance to platelet storage and transfusion practice? Transfusion medicine, 11(6), pp. 403-17. Oxford: Blackwell Scientific Publications 10.1046/j.1365-3148.2001.00340.x

Clemetson, KJ (2001). Platelet receptors for adhesion and activation. Variability as a factor in susceptibility to cardiovascular diseases. Italian heart journal, 2(11), pp. 816-8. Roma: Centro Editoriale Pubblicitario Italiano CEPI

Clemetson, KJ (2001). Platelet glycoproteins and their role in diseases. Transfusion clinique et biologique, 8(3), pp. 155-62. Paris: Elsevier Masson SAS 10.1016/S1246-7820(01)00184-7

Du, XY; Navdaev, A; Clemetson, JM; Magnenat, E; Wells, TN; Clemetson, KJ (2001). Bilinexin, a snake C-type lectin from Agkistrodon bilineatus venom agglutinates platelets via GPIb and alpha2beta1. Thrombosis and haemostasis, 86(5), pp. 1277-83. Stuttgart: Schattauer

Furihata, K; Clemetson, KJ; Deguchi, H; Kunicki, TJ (2001). Variation in human platelet glycoprotein VI content modulates glycoprotein VI-specific prothrombinase activity. Arteriosclerosis, thrombosis, and vascular biology, 21(11), pp. 1857-63. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1161/hq1001.096643

Clemetson, KJ; Clemetson, JM (2001). Platelet collagen receptors. Thrombosis and haemostasis, 86(1), pp. 189-97. Stuttgart: Schattauer

Navdaev, A; Dörmann, D; Clemetson, JM; Clemetson, KJ (2001). Echicetin, a GPIb-binding snake C-type lectin from Echis carinatus, also contains a binding site for IgMkappa responsible for platelet agglutination in plasma and inducing signal transduction. Blood, 97(8), pp. 2333-41. Washington, D.C.: American Society of Hematology 10.1182/blood.V97.8.2333

Navdaev, A; Clemetson, JM; Polgar, J; Kehrel, BE; Glauner, M; Magnenat, E; Wells, TN; Clemetson, KJ (2001). Aggretin, a heterodimeric C-type lectin from Calloselasma rhodostoma (malayan pit viper), stimulates platelets by binding to alpha 2beta 1 integrin and glycoprotein Ib, activating Syk and phospholipase Cgamma 2, but does not involve the glycoprotein VI/Fc receptor gamma chain collagen receptor. Journal of biological chemistry, 24(276), pp. 20882-9. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M101585200

Dörmann, D; Clemetson, JM; Navdaev, A; Kehrel, BE; Clemetson, KJ (2001). Alboaggregin A activates platelets by a mechanism involving glycoprotein VI as well as glycoprotein Ib. Blood, 97(4), pp. 929-36. Washington, D.C.: American Society of Hematology 10.1182/blood.V97.4.929

Eiberger, J; Degen, J; Romualdi, A; Deutsch, U; Willecke, K; Söhl, G (2001). Connexin genes in the mouse and human genome. Cell communication & adhesion, 8(4-6), pp. 163-5. Basingstoke, UK: Taylor & Francis 10.3109/15419060109080717

Adams, RH; Diella, F; Hennig, S; Helmbacher, F; Deutsch, U; Klein, R (2001). The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration. Cell, 104(1), pp. 57-69. Cambridge, Mass.: Cell Press 10.1016/S0092-8674(01)00191-X

Theis, M; de Wit, C; Schlaeger, TM; Eckardt, D; Krüger, O; Döring, B; Risau, W; Deutsch, U; Pohl, U; Willecke, K (2001). Endothelium-specific replacement of the connexin43 coding region by a lacZ reporter gene. Genesis, 29(1), pp. 1-13. Hoboken, N.J.: Wiley-Liss 10.1002/1526-968X(200101)29:1<1::AID-GENE1000>3.0.CO;2-0

2000

Clemetson, KJ (2000). Vascular biology--XIth International Meeting. 5-9 September 2000, Geneva, Switzerland. IDrugs, 3(11), pp. 1307-11. London: Thomson Scientific

Dörmann, D; Clemetson, KJ; Kehrel, BE (2000). The GPIb thrombin-binding site is essential for thrombin-induced platelet procoagulant activity. Blood, 96(7), pp. 2469-78. Washington, D.C.: American Society of Hematology

Alberio, L; Safa, O; Clemetson, KJ; Esmon, CT; Dale, GL (2000). Surface expression and functional characterization of alpha-granule factor V in human platelets: effects of ionophore A23187, thrombin, collagen, and convulxin. Blood, 95(5), pp. 1694-702. Washington, D.C.: American Society of Hematology

Clemetson, KJ; Clemetson, JM; Proudfoot, AE; Power, CA; Baggiolini, M; Wells, TN (2000). Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets. Blood, 96(13), pp. 4046-54. Washington, D.C.: American Society of Hematology

1999

Ruan, J; Schmugge, M; Clemetson, KJ; Cazes, E; Combrie, R; Bourre, F; Nurden, AT (1999). Homozygous Cys542-->Arg substitution in GPIIIa in a Swiss patient with type I Glanzmann's thrombasthenia. British journal of haematology, 2(105), pp. 523-31. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.1999.01376.x

Jandrot-Perrus, M; Clemetson, KJ; Guillin, MC; Bouton, MC (1999). Binding of heparin to platelet membrane glycoprotein Ib: functional effects. Thrombosis and haemostasis, 81(2), pp. 316-7. Stuttgart: Schattauer

Clemetson, KJ (1999). Primary haemostasis: sticky fingers cement the relationship. Current Biology, 3(9), R110-2. Cambridge, Mass.: Cell Press 10.1016/S0960-9822(99)80063-3

Clemetson, JM; Polgar, J; Magnenat, E; Wells, TN; Clemetson, KJ (1999). The platelet collagen receptor glycoprotein VI is a member of the immunoglobulin superfamily closely related to FcalphaR and the natural killer receptors. Journal of biological chemistry, 41(274), pp. 29019-24. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.274.41.29019

Clemetson, KJ (1999). Platelet collagen receptors: a new target for inhibition? Haemostasis, 29(1), pp. 16-26. Basel: Karger

Fachinger, G; Deutsch, U; Risau, W (1999). Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2. Oncogene, 43(18), pp. 5948-53. Basingstoke, UK: Nature Publishing Group 10.1038/sj.onc.1202992

Adams, RH; Wilkinson, GA; Weiss, C; Diella, F; Gale, NW; Deutsch, U; Risau, W; Klein, R (1999). Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes & development, 13(3), pp. 295-306. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press 10.1101/gad.13.3.295

1998

Polgár, J; Magnenat, E; Wells, TN; Clemetson, KJ (1998). Platelet glycoprotein Ia* is the processed form of multimerin--isolation and determination of N-terminal sequences of stored and released forms. Thrombosis and haemostasis, 80(4), pp. 645-8. Stuttgart: Schattauer

Schmitz, G; Rothe, G; Ruf, A; Barlage, S; Tschöpe, D; Clemetson, KJ; Goodall, AH; Michelson, AD; Nurden, AT; Shankey, TV (1998). European Working Group on Clinical Cell Analysis: Consensus protocol for the flow cytometric characterisation of platelet function. Thrombosis and haemostasis, 79(5), pp. 885-96. Stuttgart: Schattauer

Polgár, J; Eichler, P; Greinacher, A; Clemetson, KJ (1998). Adenosine diphosphate (ADP) and ADP receptor play a major role in platelet activation/aggregation induced by sera from heparin-induced thrombocytopenia patients. Blood, 91(2), pp. 549-54. Washington, D.C.: American Society of Hematology

Kehrel, B; Wierwille, S; Clemetson, KJ; Anders, O; Steiner, M; Knight, CG; Farndale, RW; Okuma, M; Barnes, MJ (1998). Glycoprotein VI is a major collagen receptor for platelet activation: it recognizes the platelet-activating quaternary structure of collagen, whereas CD36, glycoprotein IIb/IIIa, and von Willebrand factor do not. Blood, 91(2), pp. 491-9. Washington, D.C.: American Society of Hematology

Clemetson, KJ; Polgár, J; Clemetson, JM (1998). Snake venom C-type lectins as tools in platelet research. Platelets, 9(3-4), pp. 165-9. London: Informa Healthcare 10.1080/09537109876636

Clemetson, KJ; Clemetson, JM (1998). Integrins and cardiovascular disease. Cellular and molecular life sciences, 6(54), pp. 502-13. Basel: Springer 10.1007/s000180050179

Reiss, Y; Hoch, G; Deutsch, U; Engelhardt, B (1998). T cell interaction with ICAM-1-deficient endothelium in vitro: essential role for ICAM-1 and ICAM-2 in transendothelial migration of T cells. European journal of immunology, 28(10), pp. 3086-99. Weinheim: Wiley-VCH 10.1002/(SICI)1521-4141(199810)28:10<3086::AID-IMMU3086>3.0.CO;2-Z

Knies, UE; Behrensdorf, HA; Mitchell, CA; Deutsch, U; Risau, W; Drexler, HC; Clauss, M (1998). Regulation of endothelial monocyte-activating polypeptide II release by apoptosis. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 95(21), pp. 12322-7. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.95.21.12322

Koblizek, TI; Weiss, C; Yancopoulos, GD; Deutsch, U; Risau, W (1998). Angiopoietin-1 induces sprouting angiogenesis in vitro. Current Biology, 9(8), pp. 529-32. Cambridge, Mass.: Cell Press 10.1016/S0960-9822(98)70205-2

1997

Walz, Alfred; Schmutz, Peter; Mueller, Christoph; Schnyder-Candrian, Silvia (1997). Regulation and function of the CXC chemokine ENA-78 in monocytes and its role in disease. Journal of leukocyte biology, 62(5), pp. 604-611. Society for Leukocyte Biology 10.1002/jlb.62.5.604

Polgár, J; Kramer, RM; Um, SL; Jakubowski, JA; Clemetson, KJ (1997). Human group II 14 kDa phospholipase A2 activates human platelets. Biochemical journal, 327(Pt 1), pp. 259-65. London: Portland Press

Clemetson, KJ (1997). Platelet GPIb-V-IX complex. Thrombosis and haemostasis, 78(1), pp. 266-70. Stuttgart: Schattauer

Polgár, J; Magnenat, EM; Peitsch, MC; Wells, TN; Saqi, MS; Clemetson, KJ (1997). Amino acid sequence of the alpha subunit and computer modelling of the alpha and beta subunits of echicetin from the venom of Echis carinatus (saw-scaled viper). Biochemical journal, 323(Pt 2), pp. 533-7. London: Portland Press

Polgár, J; Clemetson, JM; Kehrel, BE; Wiedemann, M; Magnenat, EM; Wells, TN; Clemetson, KJ (1997). Platelet activation and signal transduction by convulxin, a C-type lectin from Crotalus durissus terrificus (tropical rattlesnake) venom via the p62/GPVI collagen receptor. Journal of biological chemistry, 21(272), pp. 13576-83. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.272.21.13576

Mayr, T; Deutsch, U; Kühl, M; Drexler, HC; Lottspeich, F; Deutzmann, R; Wedlich, D; Risau, W (1997). Fritz: a secreted frizzled-related protein that inhibits Wnt activity. Mechanisms of development, 63(1), pp. 109-25. Shannon: Elsevier 10.1016/S0925-4773(97)00035-X

Schlaeger, TM; Bartunkova, S; Lawitts, JA; Teichmann, G; Risau, W; Deutsch, U; Sato, TN (1997). Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 94(7), pp. 3058-63. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.94.7.3058

Koblizek, TI; Runting, AS; Stacker, SA; Wilks, AF; Risau, W; Deutsch, U (1997). Tie2 receptor expression and phosphorylation in cultured cells and mouse tissues. European journal of biochemistry, 244(3), pp. 774-9. Cambridge: Blackwell Science 10.1111/j.1432-1033.1997.00774.x

Bichsel, Verena E.; Walz, Alfred; Bickel, Matthias (1997). Identification of proteins binding specifically to the 3′-untranslated region of granulocyte/macrophagecolony stimulating factor mRNA. Nucleic acids research, 25(12), pp. 2417-2423. Oxford University Press 10.1093/nar/25.12.2417

1995

Seitz, M.; Loetscher, P.; Dewald, B.; Towbin, H.; Rordorf, C.; Gallati, H.; Baggiolini, M.; Gerber, N. J. (1995). METHOTREXATE ACTION IN RHEUMATOID ARTHRITIS: STIMULATION OF CYTOKINE INHIBITOR AND INHIBITION OF CHEMOKINE PRODUCTION BY PERIPHERAL BLOOD MONONUCLEAR CELLS. Rheumatology, 34(7), pp. 602-609. Oxford University Press 10.1093/rheumatology/34.7.602

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