04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Knochenbiologie & Orthopädische Forschung
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Knochenbiologie & Orthopädische Forschung

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Number of items at this level: 102.

2024

Safari, Fatemeh; Yeoh, Wen Jie; Perret-Gentil, Saskia; Klenke, Frank; Dolder, Silvia; Hofstetter, Wilhelm; Krebs, Philippe (2024). SHIP1 deficiency causes inflammation-dependent retardation in skeletal growth. Life science alliance, 7(5) EMBO Press 10.26508/lsa.202302297

Strunz, Franziska; Gentil-Perret, Saskia; Siegrist, Mark; Bohner, Marc; Saulacic, Nikola; Hofstetter, Wilhelm (2024). Bisphosphonates do not affect healing of a critical-size defect in estrogen-deficient mice. Bone reports, 20(101739) Elsevier 10.1016/j.bonr.2024.101739

Gantenbein, Benjamin; Oswald, Katharina A C; Erbach, Georg F; Croft, Andreas S; Bermudez-Lekerika, Paola; Strunz, Franziska; Bigdon, Sebastian F; Albers, Christoph E. (2024). The Bone Morphogenetic Protein 2 Analogue L51P Enhances Spinal Fusion in Combination with BMP2 in an In Vivo Rat Tail Model. (In Press). Acta biomaterialia Elsevier 10.1016/j.actbio.2024.01.039

2023

Strunz, Franziska; Stähli, Christoph; Heverhagen, Johannes T; Hofstetter, Wilhelm; Egli, Rainer J (2023). Gadolinium-Based Contrast Agents and Free Gadolinium Inhibit Differentiation and Activity of Bone Cell Lineages. (In Press). Investigative radiology Lippincott Williams & Wilkins 10.1097/RLI.0000000000001049

Louradour, Julien; Ottersberg, Rahel; Segiser, Adrian; Olejnik, Agnieszka; Martinez-Salazar, Berenice; Siegrist, Mark; Egle, Manuel; Barbieri, Miriam; Nimani, Saranda; Alerni, Nicolò; Döring, Yvonne; Odening, Katja E.; Longnus, Sarah (2023). Simultaneous assessment of mechanical and electrical function in Langendorff-perfused ex-vivo mouse hearts. Frontiers in cardiovascular medicine, 10 Frontiers 10.3389/fcvm.2023.1293032

Santoni, Bastien Le Gars; Niggli, Luzia; Dolder, Silvia; Loeffel, Olivier; Sblendorio, Gabrielle; Maazouz, Yassine; Alexander, Duncan; Heuberger, Roman; Stähli, Christoph; Döbelin, Nicola; Bowen, Paul; Hofstetter, Wilhelm; Bohner, Marc (2023). Influence of the sintering atmosphere on the physico-chemical properties and the osteoclastic resorption of β-tricalcium phosphate cylinders. Acta biomaterialia, 169, pp. 566-578. Elsevier 10.1016/j.actbio.2023.08.012

Salzer, E; Schmitz, TC; Mouser, VHM; Vernengo, A; Gantenbein, B; Jansen, JU; Neidlinger-Wilke, C; Wilke, H-J; Grad, S; Le Maitre, CL; Tryfonidou, MA; Ito, K (2023). Ex vivo intervertebral disc cultures: degeneration-induction methods and their implications for clinical translation. European cells & materials eCM, 45, pp. 88-112. University of Wales 10.22203/eCM.v045a07

2022

Zaugg, Jonas; Pujol Giménez, Jonai; Cabra, Romina Silvia; Hofstetter, Wilhelm; Hediger, Matthias; Albrecht, Christiane (2022). New Insights into the Physiology of Iron Transport: An Interdisciplinary Approach. CHIMIA, 76(12), pp. 996-1004. 10.2533/chimia.2022.996

Bakirci, Ezgi; Guenat, O T; Ahmad, S S; Gantenbein, B (2022). Tissue engineering approaches for the repair and regeneration of the anterior cruciate ligament: towards 3D bioprinted ACL-on-chip. European cells & materials eCM, 44, pp. 21-42. University of Wales 10.22203/eCM.v044a02

Safari, Fatemeh; Yeoh, Jeremy; Siegrist, Mark; Dolder, Silvia; Strunz, Franziska; Hofstetter, Willy; Krebs, Philippe (May 2022). Inositol Phosphatase SHIP1 – a Regulator of Osteoclast Lineage Cell Development and Activity. Bone reports, 16, p. 101404. Elsevier 10.1016/j.bonr.2022.101404

Strunz, Franziska; Siegrist, Mark; Saulacic, Nikola; Bohner, Marc; Hofstetter, Willy (May 2022). Repair of a critical-size defect in estrogen-deficient mice treated with bisphosphonates. Bone reports, 16, p. 101323. Elsevier 10.1016/j.bonr.2022.101323

Kovařík, František; Fet, Victor; Gantenbein, Benjamin; Graham, Matthew R.; Yağmur, Ersen Aydin; Šťáhlavský, František; Poverennyi, Nikita M.; Novruzov, Nizami E. (2022). A revision of the genus Mesobuthus Vachon, 1950, with a description of 14 new species (Scorpiones: Buthidae). Euscorpius, 2022(348), pp. 1-189. Marshal Digital Scholar

2021

Safari, Fatemeh; Yeoh, Jeremy; Bringardner, Margaux; Siegrist, Mark; Dolder, Silvia; Strunz, Franziska; Hofstetter, Willy; Krebs, Philippe (April 2021). The inositol phosphatase SHIP1 regulates skeletal development. Bone reports, 14, p. 100795. Elsevier 10.1016/j.bonr.2021.100795

Strunz, Franziska; Siegrist, Mark; Saulacic, Nikola; Bohner, Marc; Hofstetter, Willy (April 2021). Repair of a critical size defect in osteoporotic mice. Bone reports, 14, p. 100834. Elsevier 10.1016/j.bonr.2021.100834

2020

Tekari, Adel; Egli, Rainer J.; Schmid, Veit; Justiz, Joern; Luginbuehl, Reto (2020). A novel bioreactor system capable of simulating the in vivo conditions of synovial joints. Tissue engineering. Part C, Methods, 26(12), pp. 617-627. Mary Ann Liebert 10.1089/ten.TEC.2020.0161

Safari, Fatemeh; Siegrist, Mark; Dolder, Silvia; Hartmann, Eliza; Klenke, Frank; Hofstetter, Willy (October 2020). Noggin as a regulator of bone remodelling. Bone reports, 13, p. 100460. Elsevier 10.1016/j.bonr.2020.100460

Brigger, Daniel; Riether, Carsten; van Brummelen, Robin; Mosher, Kira I; Shiu, Alicia; Ding, Zhaoqing; Zbären, Noemi; Gasser, Pascal; Guntern, Pascal; Yousef, Hanadie; Castellano, Joseph M; Storni, Federico; Graff-Radford, Neill; Britschgi, Markus; Grandgirard, Denis; Hinterbrandner, Magdalena; Siegrist, Mark; Moullan, Norman; Hofstetter, Wilhelm; Leib, Stephen L.; ... (2020). Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age. Nature metabolism, 2(8), pp. 688-702. Springer Nature 10.1038/s42255-020-0228-3

Wolf, Thomas Gerhard; Kozaczek, Christoph; Siegrist, Mark; Betthäuser, Madlena; Paqué, Frank; Briseño-Marroquín, Benjamín (2020). An Ex Vivo Study of Root Canal System Configuration and Morphology of 115 Maxillary First Premolars. Journal of endodontics, 46(6), pp. 794-800. Elsevier 10.1016/j.joen.2020.03.001

Saulacic, Nikola; Muñoz, Fernando; Kobayashi, Eizaburo; Chappuis, Vivianne; Gonzáles-Cantalapiedra, Antonio; Hofstetter, Wilhelm (2020). Effects of local application of alendronate on early healing of extraction socket in dogs. Clinical oral investigations, 24(4), pp. 1579-1589. Springer-Verlag 10.1007/s00784-019-03031-7

May, Rahel D.; Frauchiger, Daniela A.; Albers, Christoph E.; Hofstetter, Wilhelm; Gantenbein, Benjamin (2020). Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype. Neurospine, 17(1), pp. 77-87. Korean Spinal Neurosurgery Society 10.14245/ns.2040002.001

2019

Frauchiger, Daniela A; Tekari, Adel; May, Rahel Deborah; Džafo, Emina; Chan, Samantha Cw; Stoyanov, Jivko; Bertolo, Alessandro; Zhang, Xingshuo; Guerrero, Julien; Sakai, Daisuke; Schol, Jordy; Grad, Sibylle; Tryfonidou, Marianna A; Benneker, Lorin M.; Gantenbein, Benjamin (2019). FACS is more potent to fish IVD progenitor cells than magnetic and bead-based methods. Tissue engineering. Part C, Methods, 25(10), pp. 571-580. Mary Ann Liebert 10.1089/ten.TEC.2018.0375

May, Rahel Deborah; Frauchiger, Daniela Angelika; Albers, Christoph Emmanuel; Tekari, Adel; Benneker, Lorin Michael; Klenke, Frank Michael; Hofstetter, Wilhelm; Gantenbein, Benjamin (2019). Application of Cytokines of the Bone Morphogenetic Protein (BMP) Family in Spinal Fusion - Effects on the Bone, Intervertebral Discs, and Mesenchymal Stromal Cells. Current stem cell research & therapy, 14(8), pp. 618-643. Bentham Science Publishers 10.2174/1574888X14666190628103528

Zhao, Weitian; Michalik, David; Ferguson, Stephen; Hofstetter, Wily; Lemaître, Jacques; von Rechenberg, Brigitte; Bowen, Paul (2019). Rapid evaluation of bioactive Ti-based surfaces using an in vitro titration method. Nature communications, 10(1), p. 2062. Springer Nature 10.1038/s41467-019-09673-1

Gallo, Marta; Le Gars Santoni, Bastien; Douillard, Thierry; Zhang, Fei; Gremillard, Laurent; Dolder, Silvia; Hofstetter, Willy; Meille, Sylvain; Bohner, Marc; Chevalier, Jérôme; Tadier, Solène (2019). Effect of grain orientation and magnesium doping on β-tricalcium phosphate resorption behavior. Acta biomaterialia, 89, pp. 391-402. Elsevier 10.1016/j.actbio.2019.02.045

Frauchiger, Daniela A; Tekari, Adel; May, Rahel; Dzafo, Emina; Chan, Samantha C.W.; Stoyanov, Jivko; Bertolo, Alessandro; Zhang, Xingshuo; Sakai, Daisuke; Schol, Jordy; Grad, Sibylle; Tryfonidou, Marianna; Benneker, Lorin M.; Gantenbein, Benjamin (2019). Different isolation methods for nucleus pulposus progenitor cells. In: 7th International Congress on Biotechnologies for Spinal Surgery (BioSpine7). Rom, Italy. 3-5 April 2019.

May, Rahel D.; Frauchiger, Daniela A.; Albers, Christoph E.; Benneker, Lorin M.; Hofstetter, Wilhelm; Gantenbein, Benjamin (2019). Stimulation of intervertebral disc cells in alginate bead culture with bone morphogenetic protein 2 and/or L51P. In: 7th International Congress on Biotechnologies for Spinal Surgery (BioSpine7). 3-5 April.

Zhang, Xingshuo; Frauchiger, Daniela A.; May, Rahel D.; Dzafo, Emina; Tekari, Adel; Benneker, Lorin M.; Sakai, Daisuke; Tryfonidou, Marianna; Gantenbein, Benjamin (2019). Can PPARδ agonist increase cell yield of nucleus pulposus progenitor cells positive for angiopoietin-1 receptor (= TIE2) after cell isolation? In: 7th International Congress on Biotechnologies for Spinal Surgery (BioSpine7). Rom, Italy. 3-5 April.

Tekari, Adel; Chan, Samantha C.W.; Sakai, Daisuke; Grad, Sibylle; Gantenbein, Benjamin (2019). Correction to: Angiopoietin-1 receptor Tie2 distinguishes multipotent differentiation capability in bovine coccygeal nucleus pulposus cells. Stem cell research & therapy, 10(1) BioMed Central 10.1186/s13287-019-1150-z

May, Rahel Deborah; Frauchiger, D.A.; Albers, Christoph E.; Benneker, Lorin M.; Hofstetter, Wilhelm; Gantenbein, Benjamin (2019). Stimulation of intervertebral disc cells in alginate bead culture with bone morphogenetic protein 2 and/or L51P. In: TERMIS EU chapter meeting. Rhodes, Greece. 27th-31s tMay.

Frauchiger, D.A.; May, Rahel Deborah; Dzafo, E.; Zhang, Xingshuo; Stoyanov, J.; Bertolo, A.; Benneker, Lorin Michael; Sakai, D.; Grad, S.; Tryfonidou, M.A.; Gantenbein, Benjamin (2019). FACS reveals more Pluripotent Intervertebral Disc Progenitor Cells compared to MACS and pluriSelect. In: TERMIS European Chapter Meeting 2019 (p. 898). Davos eCMjournal: www.ecmjournal.org

2018

Hauser, Michel; Siegrist, Mark; Denzer, Alain; Saulacic, Nikola; Grosjean, Joël; Bohner, Marc; Hofstetter, Wilhelm (2018). Bisphosphonates reduce biomaterial turnover in healing of critical-size rat femoral defects. Journal of orthopaedic surgery, 26(3), p. 2309499018802487. Hong Kong University Press 10.1177/2309499018802487

Moor, Matthias B; Ramakrishnan, Suresh K; Legrand, Finola; Dolder, Silvia; Siegrist, Mark; Durussel, Fanny; Centeno, Gabriel; Firsov, Dmitri; Hynes, Nancy E; Hofstetter, Wilhelm; Bonny, Olivier (2018). Redox-Dependent Bone Alkaline Phosphatase Dysfunction Drives Part of the Complex Bone Phenotype in Mice Deficient for Memo1. JBMR plus, 2(4), pp. 195-205. Wiley 10.1002/jbm4.10034

Hauser, Michel; Siegrist, Mark; Keller, Irene; Hofstetter, Wilhelm (2018). Healing of fractures in osteoporotic bones in mice treated with bisphosphonates - A transcriptome analysis. Bone, 112, pp. 107-119. Elsevier 10.1016/j.bone.2018.04.017

Uster, Stephanie Sarah; Matos Coelho, Fernanda; Aeberli, Daniel; Stein, Jens Volker; Hofstetter, Wilhelm; Engelhardt, Britta; Seitz, Michael (2018). TNFα blockade mediates bone protection in antigen-induced arthritis by reducing osteoclast precursor supply. Bone, 107, pp. 56-65. Elsevier 10.1016/j.bone.2017.10.020

2017

Krismer, Anna; Cabra, Romina Silvia; May, Rahel; Frauchiger, Daniela Angelika; Kohl, Sandro; Ahmad, Sufian; Gantenbein, Benjamin (2017). The biologic response of human anterior cruciate ligamentocytes on collagen-patches to platelet-rich plasma formulations with and without leucocytes. Journal of orthopaedic research, 35(12), pp. 2733-2739. Wiley 10.1002/jor.23599

Rieben, Robert; Hofstetter, Wilhelm (17 November 2017). Wo die kranken Mäuse leben (Interview mit Prof. Dr. Wilhelm Hofstetter und Prof. Dr. Robert Rieben). Neue Zürcher Zeitung NZZ, p. 55. Verlag Neue Zürcher Zeitung

Diaz Romero, Jose; Kürsener, Sibylle; Kohl, Sandro; Nesic, Dobrila (2017). S100B + A1 CELISA: A Novel Potency Assay and Screening Tool for Redifferentiation Stimuli of Human Articular Chondrocytes. Journal of cellular physiology, 232(6), pp. 1559-1570. Wiley 10.1002/jcp.25682

Schaller, Benoît; Saulacic, Nikola; Beck, Stefan; Imwinkelried, Thomas; Liu, Edwin Wei Yang; Nakahara, Ken; Hofstetter, Wilhelm; Iizuka, Tateyuki (2017). Osteosynthesis of partial rib osteotomy in a miniature pig model using human standard-sized magnesium plate/screw systems: Effect of cyclic deformation on implant integrity and bone healing. Journal of cranio-maxillo-facial surgery, 45(6), pp. 862-871. Elsevier 10.1016/j.jcms.2017.03.018

Zurmühle, CA; Milella, Marco; Steppacher, SD; Hanke, MS; Albers, Christoph; Tannast, M (2017). ArtiFacts: Femoroacetabular Impingement-A New Pathology? Clinical orthopaedics and related research, 475(4), pp. 973-980. Springer 10.1007/s11999-017-5270-4

Zhang, Shengye; Wotzkow Alvarez, Carlos; Bongoni, Anjan K; Shaw-Boden, Jane; Siegrist, Mark; Taddeo, Adriano; Blank, Fabian; Hofstetter, Wilhelm; Rieben, Robert (2017). Role of the plasma cascade systems in ischemia/reperfusion injury of bone. Bone, 97, pp. 278-286. Elsevier 10.1016/j.bone.2016.12.007

Ruef, Nina; Dolder, Silvia; Aeberli, Daniel; Seitz, Michael; Balani, Deepak; Hofstetter, Wilhelm (2017). Granulocyte-macrophage colony-stimulating factor-dependent CD11c-positive cells differentiate into active osteoclasts. Bone, 97, pp. 267-277. Elsevier 10.1016/j.bone.2017.01.036

Albano, Giuseppe; Dolder, Silvia; Siegrist, Mark; Mercier-Zuber, Annie; Auberson, Muriel; Stoudmann, Candice; Hofstetter, Wilhelm; Bonny, Olivier; Fuster, Daniel Guido (2017). Increased bone resorption by osteoclast-specific deletion of the sodium/calcium exchanger isoform 1 (NCX1). Pflügers Archiv : European journal of physiology, 469(2), pp. 225-233. Springer 10.1007/s00424-016-1923-5

Egli, Rainer; Keel, Marius; Cullmann, Jennifer; Bastian, Johannes Dominik (2017). Secure Screw Placement in Management of Acetabular Fractures Using the Suprapectineal Quadrilateral Buttress Plate. BioMed research international, 2017, p. 8231301. Hindawi Publishing Corporation 10.1155/2017/8231301

Krismer, Anna; Geissberger, Christian Andreas; Bakirci, Ezgi; Cabra, Romina Silvia; Kohl, Sandro; Gantenbein, Benjamin (2017). Strain-controlled organ culture of bone-ligament-bone human-derived anterior cruciate ligaments an ex-vivo model to investigate degenerative and regenerative therapy. European cells & materials eCM, 33(Suppl. 2), p. 228. University of Wales

Krismer, Anna; Cabra, Romina Silvia; May, Rahel Deborah; Kohl, Sandro; Ahmad, Sufian; Gantenbein, Benjamin (2017). Comparing two common production methods for platelet-rich plasma and the boosting effect for human anterior cruciate ligamentocytes (Unpublished). In: TERMIS-EU Chapter. Davos. June 2017.

2016

Saulacic, Nikola; Nakahara, Ken; Iizuka, Tateyuki; Haga-Tsujimura, Maiko; Hofstetter, Wilhelm; Scolozzi, Paolo (2016). Comparison of two protocols of periosteal distraction osteogenesis in a rabbit calvaria model. Journal of biomedical materials research. Part B - applied biomaterials, 104(6), pp. 1121-1131. John Wiley & Sons 10.1002/jbm.b.33461

Xie, Wenjie; Dolder, Silvia; Siegrist, Mark; Wetterwald, Antoinette; Hofstetter, Wilhelm (2016). Glutamate Receptor Agonists and Glutamate Transporter Antagonists Regulate Differentiation of Osteoblast Lineage Cells. Calcified tissue international, 99(2), pp. 142-154. Springer 10.1007/s00223-016-0129-3

Xie, Wenjie; Lorenz, Sebastian; Dolder, Silvia; Hofstetter, Wilhelm (2016). Extracellular Iron is a Modulator of the Differentiation of Osteoclast Lineage Cells. Calcified tissue international, 98(3), pp. 275-283. Springer 10.1007/s00223-015-0087-1

Schaller, Benoît; Saulacic, Nikola; Imwinkelried, Thomas; Beck, Stefan; Liu, Edwin Wei Yang; Gralla, Jan; Nakahara, Ken; Hofstetter, Wilhelm; Iizuka, Tateyuki (2016). In vivo degradation of magnesium plate/screw osteosynthesis implant systems: Soft and hard tissue response in a calvarial model in miniature pigs. Journal of cranio-maxillo-facial surgery, 44(3), pp. 309-317. Elsevier 10.1016/j.jcms.2015.12.009

Aeberli, Daniel; Kamgang, Richard; Balani, Deepak; Hofstetter, Wilhelm; Villiger, Peter; Seitz, Michael (2016). Regulation of peripheral classical and non-classical monocytes on infliximab treatment in patients with rheumatoid arthritis and ankylosing spondylitis. RMD open, 2(1), e000079. BMJ Publishing Group 10.1136/rmdopen-2015-000079

Schaller, Benoît; Saulacic, Nikola; Beck, Stefan; Imwinkelried, Thomas; Goh, Bee Tin; Nakahara, Ken; Hofstetter, Wilhelm; Iizuka, Tateyuki (2016). In vivo degradation of a new concept of magnesium-based rivet-screws in the minipig mandibular bone. Materials science & engineering C, 69, pp. 247-254. Elsevier 10.1016/j.msec.2016.06.085

Stok, Kathryn S; Besler, Bryce A; Steiner, Thomas H; Villarreal Escudero, Ana V; Zulliger, Martin A; Wilke, Markus; Atal, Kailash; Quintin, Aurelie; Koller, Bruno; Müller, Ralph; Nesic, Dobrila (2016). Three-Dimensional Quantitative Morphometric Analysis (QMA) for In Situ Joint and Tissue Assessment of Osteoarthritis in a Preclinical Rabbit Disease Model. PLoS ONE, 11(1), e0147564. Public Library of Science 10.1371/journal.pone.0147564

2015

Schär, Michael O; Diaz-Romero, Jose; Kohl, Sandro; Zumstein, Matthias A; Nesic, Dobrila (2015). Platelet-rich concentrates differentially release growth factors and induce cell migration in vitro. Clinical orthopaedics and related research, 473(5), pp. 1635-1643. Springer 10.1007/s11999-015-4192-2

Jülke, Henriette; Mainil-Varlet, Pierre; Jakob, Roland P; Brehm, Walter; Schäfer, Birgit; Nesic, Dobrila (2015). The Role of Cells in Meniscal Guided Tissue Regeneration: A Proof of Concept Study in a Goat Model. Cartilage, 6(1), pp. 20-29. Sage 10.1177/1947603514548213

Albano, Giuseppe; Moor, Matthias; Dolder, Silvia; Siegrist, Mark; Wagner, Carsten A.; Biber, Jürg; Hernando, Nati; Hofstetter, Wilhelm; Bonny, Olivier; Fuster, Daniel Guido (2015). Sodium-Dependent Phosphate Transporters in Osteoclast Differentiation and Function. PLoS ONE, 10(4), e0125104. Public Library of Science 10.1371/journal.pone.0125104

Tekari, Adel; Luginbuehl, Reto; Hofstetter, Wilhelm; Egli, Rainer (2015). Transforming growth factor beta signaling is essential for the autonomous formation of cartilage-like tissue by expanded chondrocytes. PLoS ONE, 10(3), e0120857. Public Library of Science 10.1371/journal.pone.0120857

2014

Choy, John; Albers, Christoph; Siebenrock, Klaus-Arno; Dolder, Silvia; Hofstetter, Wilhelm; Klenke, Frank M. (2014). Incorporation of RANKL promotes osteoclast formation and osteoclast activity on β-TCP ceramics. Bone, 69, pp. 80-88. Elsevier 10.1016/j.bone.2014.09.013

Tekari, Adel; Luginbuehl, Reto; Hofstetter, Wilhelm; Egli, Rainer (2014). Chondrocytes expressing intracellular collagen type II enter the cell cycle and co-express collagen type I in monolayer culture. Journal of orthopaedic research, 32(11), pp. 1503-1511. Wiley 10.1002/jor.22690

Diaz Romero, Jose; Quintin, Aurelie; Schoenholzer, Eric; Pauli, Chantal; Despont, Alain; Zumstein, Matthias; Kohl, Sandro; Nesic, Dobrila (2014). S100A1 and S100B expression patterns identify differentiation status of human articular chondrocytes. Journal of cellular physiology, 229(8), pp. 1106-1117. Wiley 10.1002/jcp.24547

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

2013

Leunig, M.; Jüni, P.; Werlen, S.; Limacher, A.; Nüesch, E.; Pfirrmann, C. W.; Trelle, S.; Odermatt, A.; Hofstetter, Wilhelm; Ganz, R.; Reichenbach, Stephan (2013). Prevalence of cam and pincer-type deformities on hip MRI in an asymptomatic young Swiss female population: a cross-sectional study. Osteoarthritis and cartilage, 21(4), pp. 544-550. Elsevier 10.1016/j.joca.2013.01.003

Albers, Christoph E; Hofstetter, Wilhelm; Siebenrock, Klaus A; Landmann, Regine; Klenke, Frank M. (2013). In vitro cytotoxicity of silver nanoparticles on osteoblasts and osteoclasts at antibacterial concentrations. Nanotoxicology, 7(1), pp. 30-36. London: Informa Healthcare 10.3109/17435390.2011.626538

Montjovent, Marc-Oliver; Siegrist, Mark; Klenke, Frank M; Wetterwald, Antoinette; Dolder, Silvia; Hofstetter, Wilhelm (2013). Expression of antagonists of WNT and BMP signaling after non-rigid fixation of osteotomies. Bone, 53(1), pp. 79-86. New York, N.Y.: Elsevier 10.1016/j.bone.2012.11.027

Braun, T; Lepper, J; Ruiz Heiland, G; Hofstetter, W; Siegrist, M; Lezuo, P; Gaestel, M; Rumpler, M; Thaler, R; Klaushofer, K; Distler, JH; Schett, G; Zwerina, J (2013). Mitogen-activated protein kinase 2 regulates physiological and pathological bone turnover. Journal of bone and mineral research, 4(4), pp. 936-947. Hoboken, N.J.: Wiley-Blackwell 10.1002/jbmr.1816

Hofstetter, Wilhelm; Sehr, Harald; De Wild, Michael; Portenier, Jeannette; Gobrecht, Jens; Hunziker, Ernst Bruno (2013). Modulation of human osteoblasts by metal surface chemistry. Journal of biomedical materials research. Part A, 101(8), pp. 2355-2364. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.a.34541

Choy, John; Hofstetter, Wilhelm; Klenke, Frank M. (2013). RANKL immobilized on β-TCP induces and maintains osteoclast formation. Bone Abstracts, 1, PP227. Bioscientifica 10.1530/boneabs.1.PP227

2012

Albers, Christoph E; Hofstetter, Wilhelm; Sebald, Hans-Jörg; Sebald, Walter; Siebenrock, Klaus A; Klenke, Frank M (2012). L51P - A BMP2 variant with osteoinductive activity via inhibition of Noggin. Bone, 51(3), pp. 401-6. New York, N.Y.: Elsevier 10.1016/j.bone.2012.06.020

Sebald, Hans-Jörg; Klenke, Frank M; Siegrist, Mark; Albers, Christoph E; Sebald, Walter; Hofstetter, Wilhelm (2012). Inhibition of endogenous antagonists with an engineered BMP-2 variant increases BMP-2 efficacy in rat femoral defect healing. Acta biomaterialia, 8(10), pp. 3816-20. Amsterdam: Elsevier 10.1016/j.actbio.2012.06.036

Balani, Deepak; Aeberli, Daniel; Hofstetter, Willy; Seitz, Michael (2012). Interleukin-17A stimulates granulocyte-macrophage colony-stimulating factor release by murine osteoblasts in the presence of 1,25-dihydroxyvitamin D(3) and inhibits murine osteoclast development in vitro. Arthritis & rheumatism, 65(2), pp. 236-246. Hoboken, N.J.: Wiley-Blackwell 10.1002/art.37762

Ruiz-Heiland, G; Horn, A; Zerr, P; Hofstetter, W; Baum, W; Stock, M; Distler, JH; Nimmerjahn, F; Schett, G; Zwerina, J (2012). Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis. Annals of the rheumatic diseases, 3(3), pp. 400-407. London: BMJ Publishing Group 10.1136/ard.2010.148262

2011

Broggini, N; Hofstetter, W; Hunziker, E; Bosshardt, DD; Bornstein, MM; Seto, I; Weibrich, G; Buser, D (2011). The Influence of PRP on Early Bone Formation in Membrane Protected Defects. A Histological and Histomorphometric Study in the Rabbit Calvaria. Clinical implant dentistry and related research, 13(1), pp. 1-12. Oxford: Blackwell 10.1111/j.1708-8208.2009.00266.x

Reichenbach, Stephan; Leunig, Michael; Werlen, Stefan; Nüesch, Eveline; Pfirrmann, Christian W; Bonel, Harald; Odermatt, Alex; Hofstetter, Willy; Ganz, Reinhold; Jüni, Peter (2011). Association between cam-type deformities and magnetic resonance imaging-detected structural hip damage: a cross-sectional study in young men. Arthritis & rheumatism, 63(12), pp. 4023-4030. Hoboken, N.J.: Wiley-Blackwell 10.1002/art.30589

Atanga, Elvis; Dolder, Silvia; Dauwalder, Tina; Wetterwald, Antoinette; Hofstetter, Willy (2011). TNFα inhibits the development of osteoclasts through osteoblast-derived GM-CSF. Bone, 49(5), pp. 1090-100. New York, N.Y.: Elsevier 10.1016/j.bone.2011.08.003

Bastian, Johannes Dominik; Egli, Rainer J; Ganz, Reinhold; Hofstetter, Willy; Leunig, Michael (2011). Chondrocytes within osteochondral grafts are more resistant than osteoblasts to tissue culture at 37°C. Journal of investigative surgery, 24(1), pp. 28-34. New York, N.Y.: Taylor & Francis 10.3109/08941939.2010.523511

2010

Wernike, E; Montjovent, MO; Liu, Y; Wismeijer, D; Hunziker, EB; Siebenrock, KA; Hofstetter, W; Klenke, FM (2010). VEGF incorporated into calcium phosphate ceramics promotes vascularisation and bone formation in vivo. European cells & materials eCM, 19, pp. 30-40. Aberystwyth (UK): University of Wales

Hofstetter, Willy; Siegrist, Mark; Simonin, Alexandre; Bonny, Olivier; Fuster, Daniel G (2010). Sodium/hydrogen exchanger NHA2 in osteoclasts: subcellular localization and role in vitro and in vivo. Bone, 47(2), pp. 331-340. New York, N.Y.: Elsevier 10.1016/j.bone.2010.04.605

Wernike, E; Hofstetter, W; Liu, Y; Wu, G; Sebald, HJ; Wismeijer, D; Hunziker, EB; Siebenrock, KA; Klenke, FM (2010). Long-term cell-mediated protein release from calcium phosphate ceramics. Journal of biomedical materials research, 92(2), pp. 463-74. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.a.32411

Bastian, Johannes Dominik; Egli, RJ; Hofstetter, W; Leunig, M (2010). Chondrocyte function after osteochondral transfer: comparison of concave and plane punches. Archives of orthopaedic and trauma surgery, 130(3), pp. 341-6. Berlin: Springer-Verlag 10.1007/s00402-009-0867-z

Reichenbach, S; Jüni, P; Werlen, S; Nüesch, E; Pfirrmann, CW; Trelle, S; Odermatt, A; Hofstetter, W; Ganz, R; Leunig, M (2010). Prevalence of cam-type deformity on hip magnetic resonance imaging in young males: a cross-sectional study. Arthritis & rheumatism, 62(9), pp. 1319-1327. Hoboken, N.J.: Wiley-Blackwell 10.1002/acr.20198

Egermann, M; Heil, P; Tami, A; Ito, K; Janicki, P; Von Rechenberg, B; Hofstetter, W; Richards, PJ (2010). Influence of defective bone marrow osteogenesis on fracture repair in an experimental model of senile osteoporosis. Journal of orthopaedic research, 28(6), pp. 798-804. Hoboken, N.J.: Wiley 10.1002/jor.21041

2009

Bastian, J. D.; Egli, R. J.; Ganz, R.; Hofstetter, W.; Leunig, M. (2009). Differential response of porcine osteoblasts and chondrocytes in cell or tissue culture after 5-aminolevulinic acid-based photodynamic therapy. Osteoarthritis and cartilage, 17(4), pp. 539-46. Amsterdam: Elsevier 10.1016/j.joca.2008.08.005

Leunig, M; Reichenbach, S; Trelle, S; Werlen, S; Odermatt, A; Hofstetter, W (2009). Hueft-Impingment: ein neuer Risikofaktor oder Coxarthrose? Schweizerisches Medizin-Forum SMF / Swiss medical forum / Forum médical suisse FMS, 2009(9), pp. 708-710. Basel: EMH Editores Medicorum Helveticorum

2008

Klenke, FM; Liu, Y; Yuan, H; Hunziker, EB; Siebenrock, KA; Hofstetter, W (2008). Impact of pore size on the vascularization and osseointegration of ceramic bone substitutes in vivo. Journal of biomedical materials research. Part A, 85(3), pp. 777-86. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.a.31559

Gengenbacher, M; Sebald, H-J; Villiger, P M; Hofstetter, W; Seitz, M (2008). Infliximab inhibits bone resorption by circulating osteoclast precursor cells in patients with Rheumatoid Arthritis and Ankylosing Spondylitis. Annals of the rheumatic diseases, 67(5), pp. 620-4. London: BMJ Publishing Group 10.1136/ard.2007.076711

Fraitzl, Christian R; Egli, Rainer J; Wingenfeld, Carsten; Ganz, Reinhold; Hofstetter, Willy; Leunig, Michael (2008). Time course of biological activity in fresh murine osteochondral allografts paralleled to the recipient's immune response. Journal of investigative surgery, 21(3), pp. 109-17. New York, N.Y.: Taylor & Francis 10.1080/08941930802043540

Egli, Rainer J; Di Criscio, Agostino; Hempfing, Axel; Schoeniger, Ralf; Ganz, Reinhold; Hofstetter, Willy; Leunig, Michael (2008). In vitro resistance of articular chondrocytes to 5-Aminolevulinic acid based photodynamic therapy. Lasers in surgery and medicine, 40(4), pp. 282-90. Hoboken, N.J.: Wiley-Liss 10.1002/lsm.20625

Egli, Rainer J; Bastian, Johannes D; Ganz, Reinhold; Hofstetter, Willy; Leunig, Michael (2008). Hypoxic expansion promotes the chondrogenic potential of articular chondrocytes. Journal of orthopaedic research, 26(7), pp. 977-85. Hoboken, N.J.: Wiley 10.1002/jor.20603

Wagner, S; Gollwitzer, H; Wernicke, D; Langer, R; Siebenrock, KA; Hofstetter, W (2008). Interface membrane fibroblasts around aseptically loosened endoprostheses express MMP-13. Journal of orthopaedic research, 26(2), pp. 143-52. Hoboken, N.J.: Wiley 10.1002/jor.20494

Wernike, Ellen; Li, Zhen; Alini, Mauro; Grad, Sibylle (2008). Effect of reduced oxygen tension and long-term mechanical stimulation on chondrocyte-polymer constructs. Cell and tissue research, 331(2), pp. 473-83. Heidelberg: Springer 10.1007/s00441-007-0500-9

2007

Egli, Rainer J; Schober, Martin; Hempfing, Axel; Ganz, Reinhold; Hofstetter, Willy; Leunig, Michael (2007). Sensitivity of osteoblasts, fibroblasts, bone marrow cells, and dendritic cells to 5-aminolevulinic acid based photodynamic therapy. Journal of photochemistry and photobiology. B - biology, 89(2-3), pp. 70-7. Amsterdam: Elsevier 10.1016/j.jphotobiol.2007.09.005

2006

Wagner, Susanne; Hofstetter, Willy; Chiquet, Matthias; Mainil-Varlet, Pierre; Stauffer, Edouard; Jansson, Volkmar; Siebenrock, Klaus A (2006). Femoro-azetabuläres Impingement: Eine präarthrotische Deformität? Zeitschrift für Orthopädie und ihre Grenzgebiete, 144(3), pp. 248-51. Stuttgart: Thieme

Dolder, Silvia; Hofstetter, Willy; Wetterwald, Antoinette; Mühlbauer, Roman C; Felix, Rolf (2006). Effect of monoterpenes on the formation and activation of osteoclasts in vitro. Journal of bone and mineral research, 21(4), pp. 647-55. Hoboken, N.J.: Wiley-Blackwell 10.1359/JBMR.060111

Balga, Renate; Wetterwald, Antoinette; Portenier, Jeannette; Dolder, Silvia; Mueller, Christoph; Hofstetter, Willy (2006). Tumor necrosis factor-alpha: alternative role as an inhibitor of osteoclast formation in vitro. Bone, 39(2), pp. 325-35. New York, N.Y.: Elsevier 10.1016/j.bone.2006.02.056

Jost-Albrecht, Katrin; Hofstetter, Willy (2006). Gene expression by human monocytes from peripheral blood in response to exposure to metals. Journal of biomedical materials research. Part B - applied biomaterials, 76(2), pp. 449-55. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.b.30389

Lau, Y S; Sabokbar, A; Giele, H; Cerundolo, V; Hofstetter, W; Athanasou, N A (2006). Malignant melanoma and bone resorption. British journal of cancer, 94(10), pp. 1496-503. Basingstoke: Nature Publishing Group 10.1038/sj.bjc.6603103

2005

Sommer, Beatrice; Felix, Rolf; Sprecher, Christoph; Leunig, Michael; Ganz, Reinhold; Hofstetter, Willy (2005). Wear particles and surface topographies are modulators of osteoclastogenesis in vitro. Journal of biomedical materials research. Part A, 72(1), pp. 67-76. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.a.30202

Wetli, Herbert A; Brenneisen, Rudolf; Tschudi, Ingrid; Langos, Manuela; Bigler, Peter; Sprang, Thomas; Schürch, Stefan; Mühlbauer, Roman C (2005). A gamma-glutamyl peptide isolated from onion (Allium cepa L.) by bioassay-guided fractionation inhibits resorption activity of osteoclasts. Journal of agricultural and food chemistry, 53(9), pp. 3408-14. Columbus, Ohio: American Chemical Society 10.1021/jf040457i

Lazzarato, Loretta; Rolando, Barbara; Lolli, Marco L; Tron, Gian Cesare; Fruttero, Roberta; Gasco, Alberto; Deleide, Guido; Guenther, Harald L (2005). Synthesis of NO-donor bisphosphonates and their in-vitro action on bone resorption. Journal of medicinal chemistry, 48(5), pp. 1322-9. Easton, Pa.: American Chemical Society 10.1021/jm040830d

2004

Spichiger, Miriam; Mühlbauer, Roman C; Brenneisen, Rudolf (2004). Determination of menthol in plasma and urine of rats and humans by headspace solid phase microextraction and gas chromatography--mass spectrometry. Journal of chromatography. B - analytical technologies in the biomedical and life sciences, 799(1), pp. 111-7. New York, N.Y.: Elsevier 10.1016/j.jchromb.2003.10.022

Rothenfluh, Dominique A; Demhartner, Thomas J; Fraitzl, Christian R; Cecchini, Marco G; Ganz, Reinhold; Leunig, Michael (2004). Potential role of pre-existing blood vessels for vascularization and mineralization of osteochondral grafts: an intravital microscopic study in mice. Acta orthopaedica Scandinavica, 75(3), pp. 359-65. Basingstoke, UK: Taylor & Francis 10.1080/00016470410001330

1997

Cecchini, M. G.; Fleisch, Herbert André; Mühlbauer, Roman C. (1997). Ipriflavone inhibits bone resorption in intact and ovariectomized rats. Calcified tissue international, 61(S1), S9-S11. Springer 10.1007/s002239900377

1991

Mühlbauer, R. C.; Bauss, F.; Schenk, R.; Janner, M.; Bosies, E.; Strein, K.; Fleisch, H. (1991). BM 21.0955, a potent new bisphosphonate to inhibit bone resorption. Journal of bone and mineral research, 6(9), pp. 1003-1011. Wiley-Blackwell

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