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van der Spoel, Evie; van Vliet, Nicolien A; Poortvliet, Rosalinde K E; Du Puy, Robert S; den Elzen, Wendy P J; Quinn, Terence J; Stott, David J; Sattar, Naveed; Kearney, Patricia M; Blum, Manuel R; Alwan, Heba; Rodondi, Nicolas; Collet, Tinh-Hai; Westendorp, Rudi G J; Ballieux, Bart E; Jukema, J Wouter; Dekkers, Olaf M; Gussekloo, Jacobijn; Mooijaart, Simon P and van Heemst, Diana (2024). Incidence and determinants of spontaneous normalization of subclinical hypothyroidism in older adults. The journal of clinical endocrinology and metabolism, 109(3), e1167-e1174. Oxford University Press 10.1210/clinem/dgad623
Röthlisberger, David; Jungo, Katharina Tabea; Bütikofer, Lukas; Poortvliet, Rosalinde K E; Gussekloo, Jacobijn; Streit, Sven (2023). Association of low blood pressure and falls: An analysis of data from the Leiden 85-plus Study. PLoS ONE, 18(12), e0295976. Public Library of Science 10.1371/journal.pone.0295976
Netzer, Seraina; Chocano-Bedoya, Patricia; Feller, Martin; Janett-Pellegri, Camilla; Wildisen, Lea; Büchi, Annina E; Moutzouri, Elisavet; Rodriguez, Elena Gonzalez; Collet, Tinh-Hai; Poortvliet, Rosalinde K E; Mc Carthy, Vera J C; Aeberli, Daniel; Aujesky, Drahomir; Westendorp, Rudi; Quinn, Terence J; Gussekloo, Jacobijn; Kearney, Patricia M; Mooijaart, Simon; Bauer, Douglas C and Rodondi, Nicolas (2023). The effect of thyroid hormone therapy on muscle function, strength and mass in older adults with subclinical hypothyroidism-an ancillary study within two randomized placebo controlled trials. Age and ageing, 52(1), afag326. Oxford University Press 10.1093/ageing/afac326
Lyko, Christina; Blum, Manuel R; Abolhassani, Nazanin; Stuber, Mirah J; Del Giovane, Cinzia; Feller, Martin; Moutzouri, Elisavet; Oberle, Jolanda; Jungo, Katharina T; Collet, Tinh-Hai; den Elzen, Wendy P J; Poortvliet, Rosalinde K E; Du Puy, Robert S; Dekkers, Olaf M; Trompet, Stella; Jukema, J Wouter; Aujesky, Drahomir; Quinn, Terry; Westendorp, Rudi; Kearney, Patricia M; ... (2022). Thyroid antibodies and levothyroxine effects in subclinical hypothyroidism: A pooled analysis of two randomized controlled trials. Journal of internal medicine, 292(6), pp. 892-903. Wiley 10.1111/joim.13544
Vidonscky Lüthold, Renata; Jungo, Katharina Tabea; Weir, Kristie Rebecca; Geier, Anne-Kathrin; Scholtes, Beatrice; Kurpas, Donata; Wild, Dorothea M G; Petrazzuoli, Ferdinando; Thulesius, Hans; Lingner, Heidrun; Assenova, Radost; Poortvliet, Rosalinde K E; Lazic, Vanja; Rozsnyai, Zsofia; Streit, Sven (2022). Understanding older patients' willingness to have medications deprescribed in primary care: a protocol for a cross-sectional survey study in nine European countries. BMC Geriatrics, 22(1), p. 920. BioMed Central 10.1186/s12877-022-03562-x
Du Puy, Robert S; Poortvliet, Rosalinde K E; Mooijaart, Simon P; Stott, David J; Quinn, Terry; Sattar, Naveed; Westendorp, Rudi G J; Kearney, Patricia M; McCarthy, Vera J C; Byrne, Stephen; Rodondi, Nicolas; Baretella, Oliver; Collet, Tinh-Hai; van Heemst, Diana; Dekkers, Olaf M; Jukema, J Wouter; Smit, Johannes W A; Gussekloo, Jacobijn; den Elzen, Wendy P J (2022). No effect of levothyroxine on hemoglobin in older adults with subclinical hypothyroidism: pooled results from two RCTs. Journal of clinical endocrinology and metabolism, 107(6), e2339-e2347. Endocrine Society 10.1210/clinem/dgac106
Bogaerts, Jonathan M K; von Ballmoos, Leonie M; Achterberg, Wilco P; Gussekloo, Jacobijn; Streit, Sven; van der Ploeg, Milly A; Drewes, Yvonne M; Poortvliet, Rosalinde K E (2022). Do we AGREE on the targets of antihypertensive drug treatment in older adults: a systematic review of guidelines on primary prevention of cardiovascular diseases. Age and ageing, 51(1), pp. 1-14. Oxford University Press 10.1093/ageing/afab192
Zijlstra, Laurien E; Jukema, J Wouter; Westendorp, Rudi G J; Du Puy, Robert S; Poortvliet, Rosalinde K E; Kearney, Patricia M; O'Keeffe, Linda; Dekkers, Olaf M; Blum, Manuel R.; Rodondi, Nicolas; Collet, Tinh-Hai; Quinn, Terence J; Sattar, Naveed; Stott, David J; Trompet, Stella; den Elzen, Wendy P J; Gussekloo, Jacobijn; Mooijaart, Simon P (2021). Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials. Frontiers in endocrinology, 12, p. 674841. Frontiers Research Foundation 10.3389/fendo.2021.674841
Wildisen, Lea; Feller, Martin; Del Giovane, Cinzia; Moutzouri, Elisavet; Du Puy, Robert S; Mooijaart, Simon P; Collet, Tinh-Hai; Poortvliet, Rosalinde K E; Kearney, Patricia; Quinn, Terence J; Klöppel, Stefan; Bauer, Douglas C; Peeters, Robin P; Westendorp, Rudi; Aujesky, Drahomir; Gussekloo, Jacobijn; Rodondi, Nicolas (2021). Effect of Levothyroxine Therapy on the Development of Depressive Symptoms in Older Adults With Subclinical Hypothyroidism: An Ancillary Study of a Randomized Clinical Trial. JAMA Network Open, 4(2), e2036645. American Medical Association 10.1001/jamanetworkopen.2020.36645
Jungo, Katharina Tabea; Mantelli, Sophie; Rozsnyai, Zsofia; Missiou, Aristea; Kitanovska, Biljana Gerasimovska; Weltermann, Birgitta; Mallen, Christian; Collins, Claire; Bonfim, Daiana; Kurpas, Donata; Petrazzuoli, Ferdinando; Dumitra, Gindrovel; Thulesius, Hans; Lingner, Heidrun; Johansen, Kasper Lorenz; Wallis, Katharine; Hoffmann, Kathryn; Peremans, Lieve; Pilv, Liina; Šter, Marija Petek; ... (2021). General practitioners' deprescribing decisions in older adults with polypharmacy: a case vignette study in 31 countries. BMC Geriatrics, 21(1), p. 19. BioMed Central 10.1186/s12877-020-01953-6
Rozsnyai, Zsofia; Jungo, Katharina Tabea; Reeve, Emily; Poortvliet, Rosalinde K E; Rodondi, Nicolas; Gussekloo, Jacobijn; Streit, Sven (2020). What do older adults with multimorbidity and polypharmacy think about deprescribing? The LESS study - a primary care-based survey. BMC Geriatrics, 20(1), p. 435. BioMed Central 10.1186/s12877-020-01843-x
Achterhof, Alexandra B; Rozsnyai, Zsofia; Reeve, Emily; Jungo, Katharina Tabea; Floriani, Carmen; Poortvliet, Rosalinde K E; Rodondi, Nicolas; Gussekloo, Jacobijn; Streit, Sven (2020). Potentially inappropriate medication and attitudes of older adults towards deprescribing. PLoS ONE, 15(10), e0240463. Public Library of Science 10.1371/journal.pone.0240463
Roulet, Céline; Rozsnyai, Zsofia; Jungo, Katharina Tabea; A van der Ploeg, Milly; Floriani, Carmen; Kurpas, Donata; Vinker, Shlomo; Kreitmayer Pestic, Sanda; Petrazzuoli, Ferdinando; Hoffmann, Kathryn; Viegas, Rita P A; Mallen, Christian; Tatsioni, Athina; Maisonneuve, Hubert; Collins, Claire; Lingner, Heidrun; Tsopra, Rosy; Mueller, Yolanda; Poortvliet, Rosalinde K E; Gussekloo, Jacobijn; ... (2020). Managing hypertension in frail oldest-old-The role of guideline use by general practitioners from 29 countries. PLoS ONE, 15(7), e0236064. Public Library of Science 10.1371/journal.pone.0236064
de Montmollin, Maria Karolina; Feller, Martin; Beglinger, Shanthi; McConnachie, Alex; Aujesky, Drahomir; Collet, Tinh-Hai; Ford, Ian; Gussekloo, Jacobijn; Kearney, Patricia M; McCarthy, Vera J C; Mooijaart, Simon; Poortvliet, Rosalinde K E; Quinn, Terence; Stott, David J; Watt, Torquil; Westendorp, Rudi; Rodondi, Nicolas; Bauer, Douglas C (2020). L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial. Annals of internal medicine, 172(11), pp. 709-716. American College of Physicians 10.7326/M19-3193
van der Ploeg, Milly A; Floriani, Carmen; Achterberg, Wilco P; Bogaerts, Jonathan M K; Gussekloo, Jacobijn; Mooijaart, Simon P; Streit, Sven; Poortvliet, Rosalinde K E; Drewes, Yvonne M (2020). Recommendations for (Discontinuation of) Statin Treatment in Older Adults: Review of Guidelines. Journal of the American Geriatrics Society, 68(2), pp. 417-425. Wiley-Blackwell 10.1111/jgs.16219
Mooijaart, Simon P; Du Puy, Robert S; Stott, David J; Kearney, Patricia M; Rodondi, Nicolas; Westendorp, Rudi G J; den Elzen, Wendy P J; Postmus, Iris; Poortvliet, Rosalinde K E; van Heemst, Diana; van Munster, Barbara C; Peeters, Robin P; Ford, Ian; Kean, Sharon; Messow, Claudia-Martina; Blum, Manuel R; Collet, Tinh-Hai; Watt, Torquil; Dekkers, Olaf M; Jukema, J Wouter; ... (2019). Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism. JAMA - the journal of the American Medical Association, 322(20), pp. 1977-86. American Medical Association 10.1001/jama.2019.17274
van der Ploeg, Milly A; Streit, Sven; Achterberg, Wilco P; Beers, Erna; Bohnen, Arthur M; Burman, Robert A; Collins, Claire; Franco, Fabio G; Gerasimovska-Kitanovska, Biljana; Gintere, Sandra; Gomez Bravo, Raquel; Hoffmann, Kathryn; Iftode, Claudia; Peštić, Sanda Kreitmayer; Koskela, Tuomas H; Kurpas, Donata; Maisonneuve, Hubert; Mallen, Christan D; Merlo, Christoph; Mueller, Yolanda; ... (2019). Patient Characteristics and General Practitioners' Advice to Stop Statins in Oldest-Old Patients: a Survey Study Across 30 Countries. Journal of general internal medicine, 34(9), pp. 1751-1757. Springer 10.1007/s11606-018-4795-x
Streit, Sven; Poortvliet, Rosalinde K E; Elzen, Wendy P J den; Blom, Jeanet W; Gussekloo, Jacobijn (2019). Systolic Blood Pressure and Cognitive Decline in Older Adults With Hypertension. Annals of Family Medicine, 17(2), pp. 100-107. Annals of Family Medicine 10.1370/afm.2367
Mantelli, Sophie; Jungo, Katharina Tabea; Rozsnyai, Zsofia; Reeve, Emily; Luymes, Clare H; Poortvliet, Rosalinde K E; Chiolero, Arnaud; Rodondi, Nicolas; Gussekloo, Jacobijn; Streit, Sven (2018). How general practitioners would deprescribe in frail oldest-old with polypharmacy - the LESS study. BMC family practice, 19(1), p. 169. BioMed Central 10.1186/s12875-018-0856-9
Streit, Sven; Poortvliet, Rosalinde K E; Gussekloo, Jacobijn (2018). Lower blood pressure during antihypertensive treatment is associated with higher all-cause mortality and accelerated cognitive decline in the oldest-old-data from the Leiden 85-plus Study. Age and ageing, 47(4), pp. 545-50. Oxford University Press 10.1093/ageing/afy072
O Riordan, David; Aubert, Carole Elodie; Walsh, Kieran A; van Dorland, Anette; Rodondi, Nicolas; Du Puy, Robert S; Poortvliet, Rosalinde K E; Gussekloo, Jacobijn; Sinnott, Carol; Byrne, Stephen; Galvin, Rose; Jukema, J Wouter; Mooijaart, Simon P; Baumgartner, Christine; McCarthy, Vera; Walsh, Elaine K; Collet, Tinh-Hai; Dekkers, Olaf M; Blum, Manuel R and Kearney, Patricia M (2018). Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study. BMJ open, 8(3), e019003. BMJ Publishing Group 10.1136/bmjopen-2017-019003
Streit, Sven; Gussekloo, Jacobijn; Burman, Robert A; Collins, Claire; Kitanovska, Biljana Gerasimovska; Gintere, Sandra; Gómez Bravo, Raquel; Hoffmann, Kathryn; Iftode, Claudia; Johansen, Kasper L; Kerse, Ngaire; Koskela, Tuomas H; Peštić, Sanda Kreitmayer; Kurpas, Donata; Mallen, Christian D; Maisonneuve, Hubert; Merlo, Christoph; Mueller, Yolanda; Muth, Christiane; Ornelas, Rafael H; ... (2018). Burden of cardiovascular disease across 29 countries and GPs' decision to treat hypertension in oldest-old. Scandinavian Journal of Primary Health Care, 36(1), pp. 89-98. 10.1080/02813432.2018.1426142
Stott, David J; Rodondi, Nicolas; Kearney, Patricia M; Ford, Ian; Westendorp, Rudi G J; Mooijaart, Simon P; Sattar, Naveed; Aubert, Carole E; Aujesky, Drahomir; Bauer, Douglas C; Baumgartner, Christine; Blum, Manuel R; Browne, John P; Byrne, Stephen; Collet, Tinh-Hai; Dekkers, Olaf M; den Elzen, Wendy P J; Du Puy, Robert S; Ellis, Graham; Feller, Martin; ... (2017). Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism. New England journal of medicine NEJM, 376(26), pp. 2534-2544. Massachusetts Medical Society MMS 10.1056/NEJMoa1603825
Streit, Sven; Verschoor, Marjolein; Rodondi, Nicolas; Bonfim, Daiana; Burman, Robert A; Collins, Claire; Biljana, Gerasimovska Kitanovska; Gintere, Sandra; Gómez Bravo, Raquel; Hoffmann, Kathryn; Iftode, Claudia; Johansen, Kasper L; Kerse, Ngaire; Koskela, Tuomas H; Peštić, Sanda Kreitmayer; Kurpas, Donata; Mallen, Christian D; Maisoneuve, Hubert; Merlo, Christoph; Mueller, Yolanda; ... (2017). Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries. BMC Geriatrics, 17(1), p. 93. BioMed Central 10.1186/s12877-017-0486-4
Stott, David J; Gussekloo, Jacobijn; Kearney, Patricia M; Rodondi, Nicolas; Westendorp, Rudi G J; Mooijaart, Simon; Kean, Sharon; Quinn, Terence J; Sattar, Naveed; Hendry, Kirsty; Du Puy, Robert; Den Elzen, Wendy P J; Poortvliet, Rosalinde K E; Smit, Jan W A; Jukema, J Wouter; Dekkers, Olaf M; Blum, Manuel; Collet, Tinh-Hai; McCarthy, Vera; Hurley, Caroline; ... (2017). Study protocol; Thyroid hormone Replacement for Untreated older adults with Subclinical hypothyroidism - a randomised placebo controlled Trial (TRUST). BMC Endocrine Disorders, 17(1), p. 6. BioMed Central 10.1186/s12902-017-0156-8
