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Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Sengupta, Arunima; Roldan, Nuria; Kiener, Mirjam; Froment, Laurène; Raggi, Giulia; Imler, Theo; de Maddalena, Lea; Rapet, Aude; May, Tobias; Carius, Patrick; Schneider-Daum, Nicole; Lehr, Claus-Michael; Kruithof-de Julio, Marianna; Geiser, Thomas; Marti, Thomas; Stucki, Janick D.; Hobi, Nina; Guenat, Olivier T (2022). A New Immortalized Human Alveolar Epithelial Cell Model to Study Lung Injury and Toxicity on a Breathing Lung-On-Chip System. Frontiers in toxicology, 4(840606), pp. 1-18. Frontiers Media S.A. 10.3389/ftox.2022.840606
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Berezowska, Sabina Anna; Galván Hernández, José Alberto; Langer, Rupert; Bubendorf, Lukas; Savic, Spasenija; Gugger, Mathias; Schmid, Ralph; Marti, Thomas (2017). Glycine decarboxylase and HIF-1α expression are negative prognostic factors in primary resected early-stage non-small cell lung cancer. Virchows Archiv, 470(3), pp. 323-330. Springer 10.1007/s00428-016-2057-z
Ebener, Simone; Barnowski, Sandra; Wotzkow Alvarez, Carlos; Marti, Thomas; Lopez-Rodriguez, Elena; Crestani, Bruno; Blank, Fabian; Schmid, Ralph; Geiser, Thomas; Funke, Manuela (2017). Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF. American journal of physiology - lung cellular and molecular physiology, 312(1), L42-L55. American Physiological Society 10.1152/ajplung.00119.2016
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 10PD Assessment of PD-L1 and CD47 expression together with tumor-associated TILs in resectable early stage NSCLC. Annals of oncology, 27(suppl_8), viii3. Oxford University Press 10.1093/annonc/mdw525.09
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 98O: Characterization of tumor infiltrating lymphocytes in resectable early stage non-small cell lung cancer. Journal of thoracic oncology, 11(4Suppl), S99-S99. Elsevier 10.1016/S1556-0864(16)30211-8
Marti, Thomas; Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph (2016). 23P Prolonged pemetrexed pretreatment increases efficiency of ionizing radiation combination therapy and correlates with the persistence of treatment-induced DNA damage in lung cancer cells. Journal of thoracic oncology, 11(4Suppl), S65-S65. Elsevier 10.1016/S1556-0864(16)30137-X
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph (2016). 22P Increased schedule-dependent efficiency of pemetrexed-cisplatin combination therapy eliminates resistant lung cancer stem-like cells associated with EMT. Journal of thoracic oncology, 11(4Suppl), S64-S65. Elsevier 10.1016/S1556-0864(16)30136-8
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2016). 18P Epithelial-to-mesenchymal transition (EMT) is required for resistance to anti-folate chemotherapy in lung cancer. Journal of thoracic oncology, 11(4Suppl), S63-S63. Elsevier 10.1016/S1556-0864(16)30132-0
Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT. BMC cancer, 16(125), p. 125. BioMed Central 10.1186/s12885-016-2117-4
Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Schedule-dependent increased efficiency of pemetrexed-ionizing radiation combination therapy elicits a differential DNA damage response in lung cancer cells. Cancer cell international, 16(66), p. 66. BioMed Central 10.1186/s12935-016-0346-x
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Renwang (2015). Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer. Cell death & disease, 6(e1824), e1824. Nature Publishing Group 10.1038/cddis.2015.195
Kotov, Ilya N; Siebring-van Olst, Ellen; Knobel, Philip A; van der Meulen-Muileman, Ida H; Felley-Bosco, Emanuela; van Beusechem, Victor W; Smit, Egbert F; Stahel, Rolf A; Marti, Thomas (2014). Whole genome RNAi screens reveal a critical role of REV3 in coping with replication stress. Molecular oncology, 8(8), pp. 1747-1759. Elsevier 10.1016/j.molonc.2014.07.008
Ruppen, Janine; Cortes-Dericks, Lourdes; Marconi, Emanuele; Karoubi, Golnaz; Schmid, Ralph; Peng, Renwang; Marti, Thomas; Guenat, Olivier Thierry (2014). A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. Lab on a chip, 14(6), pp. 1198-1205. Royal Society of Chemistry 10.1039/c3lc51093j
Veit, Heinz; Marti, Thomas; Winiger, Lukas (2012). Environmental changes in Northern Iceland since the Younger Dryas inferred from periglacial slope deposits. Holocene, 22(3), pp. 325-335. Los Angeles, Calif.: Sage 10.1177/0959683611423695
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Hall, Sean; Froment, Laurène; Dorn, Patrick; Berezowska, Sabina Anna; Schmid, Ralph (7 May 2017). Characterizing the DNA damage response in putative stem cells of resected normal lung and matched NSCLC patient samples. Annals of oncology, 28(suppl_2), ii4. Oxford University Press 10.1093/annonc/mdx090.013
Tièche, Colin Charles; Schmid, Ralph A. (2017). Discovery and characterization of plastic subpopulations associated with distinct hallmarks of cancer in the NSCLC cell line A549. (Dissertation, Graduate School for Cellular and Biomedical Sciences)
