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Doda, Daniela; Jimenez, Sara Alonso; Rehrauer, Hubert; Carreño, Jose F; Valsamides, Victoria; Di Santo, Stefano; Widmer, Hans Ruedi; Edge, Albert; Locher, Heiko; van der Valk, Wouter; Zhang, Jingyuan; Koehler, Karl R; Roccio, Marta (2023). Human pluripotent stem cells-derived inner ear organoids recapitulate otic development in vitro. Development, 150(19) The Company of Biologists 10.1242/dev.201865
Pilotto, Federica; Schmitz, Alexander; Maharjan, Niran; Diab, Rim; Odriozola, Adolfo; Tripathi, Priyanka; Yamoah, Alfred; Scheidegger, Olivier; Oestmann, Angelina; Dennys, Cassandra N; Sinha Ray, Shrestha; Rodrigo, Rochelle; Kolb, Stephen; Aronica, Eleonora; Di Santo, Stefano; Widmer, Hans Rudolf; Charlet-Berguerand, Nicolas; Selvaraj, Bhuvaneish T; Chandran, Siddharthan; Meyer, Kathrin; ... (2022). PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD. Acta neuropathologica, 144(5), pp. 939-966. Springer-Verlag 10.1007/s00401-022-02494-5
Croci, Davide M; Wanderer, Stefan; Strange, Fabio; Grüter, Basil E; Sivanrupan, Sivani; Andereggen, Lukas; Casoni, Daniela; von Gunten, Michael; Widmer, Hans Rudolf; Di Santo, Stefano; Fandino, Javier; Mariani, Luigi; Marbacher, Serge (2021). Tocilizumab Reduces Vasospasms, Neuronal Cell Death, and Microclot Formation in a Rabbit Model of Subarachnoid Hemorrhage. Translational stroke research, 12(5), pp. 894-904. Springer 10.1007/s12975-020-00880-3
Di Santo, Stefano; Widmer, Hans Rudolf (2021). Sustained neuronal viability by paracrine factors: new opportunities for endothelial progenitor cell secretome. Neural Regeneration Research, 16(7), pp. 1429-1430. Medknow 10.4103/1673-5374.301007
Grüter, Basil E.; Wanderer, Stefan; Strange, Fabio; Boillat, Gwendoline; Täschler, Dominik; Rey, Jeannine; Croci, Davide M; Grandgirard, Denis; Leib, Stephen; von Gunten, Michael; Di Santo, Stefano; Widmer, Hans Rudolf; Remonda, Luca; Andereggen, Lukas; Nevzati, Edin; Coluccia, Daniel; Fandino, Javier; Marbacher, Serge (2021). Patterns of Neointima Formation After Coil or Stent Treatment in a Rat Saccular Sidewall Aneurysm Model. Stroke, 52(3), pp. 1043-1052. American Heart Association 10.1161/STROKEAHA.120.032255
Eyer, Gian-Carlo; Di Santo, Stefano; Hewer, Ekkehard; Andereggen, Lukas; Seiler, Stefanie; Widmer, Hans Rudolf (2021). Co-Expression of Nogo-A in Dopaminergic Neurons of the Human Substantia Nigra Pars Compacta Is Reduced in Parkinson’s Disease. Cells, 10(12) MDPI 10.3390/cells10123368
Kissling, Cédric; Di Santo, Stefano (2020). Tumor Treating Fields - behind and beyond inhibiting the cancer cell cycle. CNS & Neurological Disorders - Drug Targets, 19(8), pp. 599-610. Bentham Science Publishers 10.2174/1871527319666200702144749
Andereggen, Lukas; Widmer, Hans Rudolf; Di Santo, Stefano; Andres, Robert Hans (2020). Functional muscle strength recovery from nail gun injury to the primary motor cortex. Regenerative medicine, 15(5), pp. 1603-1609. Future Medicine 10.2217/rme-2019-0146
Wanderer, Stefan; Grüter, Basil E.; Strange, Fabio; Sivanrupan, Sivani; Di Santo, Stefano; Widmer, Hans Rudolf; Fandino, Javier; Marbacher, Serge; Andereggen, Lukas (2020). The Role of Sartans in the Treatment of Stroke and Subarachnoid Hemorrhage: A Narrative Review of Preclinical and Clinical Studies. Brain Sciences, 10(3) MDPI 10.3390/brainsci10030153
Di Santo, Stefano; Seiler, Stefanie; Guzman, Raphael; Widmer, Hans Rudolf (2020). Endothelial Progenitor Cell-Derived Factors Exert Neuroprotection in Cultured Cortical Neuronal Progenitor Cells. Cell transplantation, 29, p. 963689720912689. Sage 10.1177/0963689720912689
Widmer, Hans Rudolf; Di Santo, Stefano (2020). Current perspectives on neurological disease: experimental models, mechanisms of disease and treatments. CNS & Neurological Disorders - Drug Targets, 19(8), pp. 558-559. Bentham Science Publishers 10.2174/187152731908201023111147
Di Santo, Stefano; Seiler, Stefanie; Ducray, Angélique D.; Widmer, Hans Rudolf (2019). Conditioned Medium from Endothelial Progenitor Cells promotes number of dopaminergic neurons and exerts neuroprotection in cultured ventral mesencephalic neuronal progenitor cells. Brain research, 1720, p. 146330. Elsevier 10.1016/j.brainres.2019.146330
Croci, Davide Marco; Wanderer, Stefan; Strange, Fabio; Grüter, Basil E; Casoni, Daniela; Sivanrupan, Sivani; Widmer, Hans Rudolf; Di Santo, Stefano; Fandino, Javier; Mariani, Luigi; Marbacher, Serge (2019). Systemic and CSF Interleukin-1α Expression in a Rabbit Closed Cranium Subarachnoid Hemorrhage Model: An Exploratory Study. Brain Sciences, 9(10) MDPI 10.3390/brainsci9100249
Di Santo, Stefano; Seiler, Stefanie; Andres, Robert; Widmer, Hans Rudolf (2019). Endothelial Progenitor Cells Conditioned Medium Supports Number of GABAergic Neurons and Exerts Neuroprotection in Cultured Striatal Neuronal Progenitor Cells. Cell transplantation, 28(4), pp. 367-378. Cognizant Communication Corporation 10.1177/0963689719835192
Sadanandan, Nadia; Di Santo, Stefano; Widmer, Hans Rudolf (2019). Another win for endothelial progenitor cells: Endothelial progenitor cell-derived conditioned medium promotes proliferation and exerts neuroprotection in cultured neuronal progenitor cells. Brain circulation, 5(3), pp. 106-111. Medknow 10.4103/bc.bc_41_19
Di Santo, Stefano; Meyer, M; Ducray, Angélique; Andereggen, Lukas; Widmer, Hans Rudolf (2018). A combination of NT-4/5 and GDNF is favorable for cultured human nigral neural progenitor cells. Cell transplantation, 27(4), pp. 648-653. Cognizant Communication Corporation 10.1177/0963689717753188
Di Santo, Stefano; Widmer, Hans R. (2018). Neurotrophic factor-based strategies to enhance survival and differentiation of neural progenitor cells toward the dopaminergic phenotype. Brain circulation, 4(3), pp. 139-141. Medknow 10.4103/bc.bc_23_18
Perez-Bouza, Alberto; Di Santo, Stefano; Seiler, Stefanie; Meyer, Morten; Andereggen, Lukas; Huber, Alexander; Guzman, Raphael; Widmer, Hans Rudolf (2017). Simultaneous Transplantation of Fetal Ventral Mesencephalic Tissue and Encapsulated Genetically Modified Cells Releasing GDNF in a Hemi-Parkinsonian Rat Model of Parkinson's Disease. Cell transplantation, 26(9), pp. 1572-1581. Cognizant Communication Corporation 10.1177/0963689717721202
Seiler, Stefanie; Di Santo, Stefano; Sahli, Sebastian; Andereggen, Lukas; Widmer, Hans Rudolf (2017). Nogo-receptor 1 antagonization in combination with neurotrophin-4/5 is not superior to single factor treatment in promoting survival and morphological complexity of cultured dopaminergic neurons. Brain research, 1668, pp. 56-64. Elsevier 10.1016/j.brainres.2017.05.015
Seiler, Stefanie; Di Santo, Stefano; Andereggen, Lukas; Widmer, Hans Rudolf (2017). Antagonization of the Nogo-Receptor 1 Enhances Dopaminergic Fiber Outgrowth of Transplants in a Rat Model of Parkinson's Disease. Frontiers in cellular neuroscience, 11, p. 151. Frontiers Research Foundation 10.3389/fncel.2017.00151
Di Santo, Stefano; Seiler, Stefanie; Ducray, Angélique; Meyer, M; Widmer, Hans Rudolf (2017). A Subpopulation of Dopaminergic Neurons Coexpresses Serotonin in Ventral Mesencephalic Cultures But Not After Intrastriatal Transplantation in a Rat Model of Parkinson's Disease. Cell transplantation, 26(4), pp. 679-691. Cognizant Communication Corporation 10.3727/096368916X693707
Di Santo, Stefano; Widmer, Hans Rudolf (2016). Paracrine factors for neurodegenerative disorders: special emphasis on Parkinson's disease. Neural Regeneration Research, 11(4), pp. 570-571. Medknow 10.4103/1673-5374.180739
Bitterli, Lukas; Afan, Samuel; Bühler, Stephan; Di Santo, Stefano; Zwahlen, Marcel; Schmidlin, Kurt; Yang, Zijang; Baumgartner, Iris; Diehm, Nicolas Alexander; Kalka, Christoph (2016). Endothelial progenitor cells as a biological marker of peripheral artery disease. Vascular medicine, 21(1), pp. 3-11. Sage 10.1177/1358863X15611225
Seiler, Stefanie; Di Santo, Stefano; Widmer, Hans Rudolf (2016). Non-canonical actions of Nogo-A and its receptors. Biochemical pharmacology, 100, pp. 28-39. Elsevier 10.1016/j.bcp.2015.08.113
Di Santo, Stefano; Fuchs, Anna-Lena; Periasamy, Ramesh; Seiler, Stefanie; Widmer, Hans Rudolf (2016). The Cytoprotective Effects of Human Endothelial Progenitor Cell-Conditioned Medium Against an Ischemic Insult Are Not Dependent on VEGF and IL-8. Cell transplantation, 25(4), pp. 735-747. Cognizant Communication Corporation 10.3727/096368916X690458
Seiler, Stefanie; Di Santo, Stefano; Widmer, Hans Rudolf (2016). Nogo-A Neutralization Improves Graft Function in a Rat Model of Parkinson's Disease. Frontiers in cellular neuroscience, 10, p. 87. Frontiers Research Foundation 10.3389/fncel.2016.00087
Schawkat, Khoschy; Di Santo, Stefano; Seiler, Stefanie; Ducray, Angélique; Widmer, Hans Rudolf (2015). Loss of Nogo-A-expressing neurons in a rat model of Parkinson's disease. Neuroscience, 288, pp. 59-72. Elsevier 10.1016/j.neuroscience.2014.12.035
Liechti, Rémy; Ducray, Angélique; Jensen, Pia; Di Santo, Stefano; Seiler, Stefanie; Jensen, Charlotte H; Meyer, Morten; Widmer, Hans Rudolf (2015). Characterization of fetal antigen 1/delta-like 1 homologue expressing cells in the rat nigrostriatal system: effects of a unilateral 6-hydroxydopamine lesion. PLoS ONE, 10(2), e0116088. Public Library of Science 10.1371/journal.pone.0116088
Di Santo, Stefano; Mina, Amir; Ducray, Angélique; Widmer, Hans Rudolf; Senn, Pascal (2014). Creatine supports propagation and promotes neuronal differentiation of inner ear progenitor cells. NeuroReport, 25(7), pp. 446-451. Lippincott Williams & Wilkins 10.1097/WNR.0000000000000112
Di Santo, Stefano; Seiler, Stefanie; Fuchs, Anna-Lena; Staudigl, Jennifer; Widmer, Hans Rudolf (2014). The secretome of endothelial progenitor cells promotes brain endothelial cell activity through PI3-kinase and MAP-kinase. PLoS ONE, 9(4), e95731. Public Library of Science 10.1371/journal.pone.0095731
Seiler, Stefanie; Pollini, Dario; Di Santo, Stefano; Widmer, Hans R. (2013). Antagonizing Nogo-receptor 1 promotes the number of cultured dopaminergic neurons and elongates their neurites. NeuroReport, 24(18), pp. 1047-1052. Lippincott Williams & Wilkins 10.1097/WNR.0000000000000063
Ortmann, Jana; Veit, Martha; Zingg, Sandra; Di Santo, Stefano; Traupe, Tobias; Yang, Zijiang; Völzmann, Jan; Dubey, Raghvendra K; Christen, Stephan; Baumgartner, Iris (2011). Estrogen receptor- but not - or GPER inhibits high glucose-induced human VSMC proliferation: potential role of ROS and ERK. Journal of clinical endocrinology and metabolism, 96(1), pp. 220-8. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2010-0943
Yang, Zijiang; von Ballmoos, Moritz Wyler; Faessler, Daniel; Voelzmann, Jan; Ortmann, Jana; Diehm, Nicolas; Kalka-Moll, Wiltrud; Baumgartner, Iris; Di Santo, Stefano; Kalka, Christoph (2010). Paracrine factors secreted by endothelial progenitor cells prevent oxidative stress-induced apoptosis of mature endothelial cells. Atherosclerosis, 211(1), pp. 103-9. Amsterdam: Elsevier 10.1016/j.atherosclerosis.2010.02.022
Wyler von Ballmoos, Moritz; Yang, Zijiang; Völzmann, Jan; Baumgartner, Iris; Kalka, Christoph; Di Santo, Stefano (2010). Endothelial Progenitor Cells Induce a Phenotype Shift in Differentiated Endothelial Cells towards PDGF/PDGFR Axis-Mediated Angiogenesis. PLoS ONE, 5(11), e14107. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0014107
Yang, Zijiang; Di Santo, Stefano; Kalka, Christoph (2010). Current developments in the use of stem cell for therapeutic neovascularisation: is the future therapy "cell-free"? Swiss medical weekly, 140, w13130. EMH Schweizerischer Ärzteverlag 10.4414/smw.2010.13130
Yang, Zijiang; von Ballmoos, Moritz Wyler; Diehm, Nicolas; Baumgartner, Iris; Kalka, Christoph; Di Santo, Stefano (2009). Call for a reference model of chronic hind limb ischemia to investigate therapeutic angiogenesis. Vascular pharmacology, 51(4), pp. 268-74. New York, N.Y.: Elsevier 10.1016/j.vph.2009.07.001
Di Santo, Stefano; Yang, Zijiang; Wyler von Ballmoos, Moritz; Voelzmann, Jan; Diehm, Nicolas; Baumgartner, Iris; Kalka, Christoph (2009). Novel cell-free strategy for therapeutic angiogenesis: in vitro generated conditioned medium can replace progenitor cell transplantation. PLoS ONE, 4(5), e5643. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0005643
Diehm, Nicolas; Di Santo, Stefano; Schaffner, Thomas; Schmidli, Juerg; Völzmann, Jan; Jüni, Peter; Baumgartner, Iris; Kalka, Christoph (2008). Severe structural damage of the seemingly non-diseased infrarenal aortic aneurysm neck. Journal of vascular surgery, 48(2), pp. 425-34. Amsterdam: Elsevier 10.1016/j.jvs.2008.03.001
Andereggen, Lukas; Reitmeir, Raluca; Di Santo, Stefano; Guzmann, Raphael; Widmer, Hans Rudolf; Marbacher, Serge; Andres, Robert (2018). Modulation of Post-Stroke Plasticity and Regeneration by Stem Cell Therapy and Exogenic Factors. In: Lapchak, P; Zhang, J (eds.) Cellular and Molecular Approaches to Regeneration & Repair. Springer Series in Translational Stroke Research (pp. 129-152). Cham: Springer 10.1007/978-3-319-66679-2_7
Di Santo, Stefano; Seiler, Stefanie; Skrzypczak, D; Bieri, T; Widmer, Hans Rudolf (2019). Conditioned medium from endothelial progenitor cells exerts neuroprotection on cultured cortical and midbrain neurons (Unpublished). In: ASNTR Annual Conference. Clearwater.
Seiler, Stefanie; Di Santo, Stefano; Widmer, Hans Rudolf (2018). Characterization of the effects of conditioned medium derived from endothelial progenitor cells on cultured striatal neuronal stem cells (Unpublished). In: ASNTR Annual Conference. Clearwater.
Seiler, Stefanie; Polloni, D; Sahli, S; Di Santo, Stefano; Widmer, Hans Rudolf (November 2014). Effects of Nogo-receptor 1 antagonization and NT4/5 administration (Unpublished). In: 24th Annual Meeting of the Network of European CNS Transplantation & Restoration (NECTAR 2014). Galway. 27.-28.11.2014.
Seiler, Stefanie; Polloni, D; Di Santo, Stefano; Widmer, Hans Rudolf (July 2014). Antagonization of Nogo-receptor 1 in combination with NT4/5 administration leads to higher dopaminergic cell densities as compared to single factor treatment (Unpublished). In: 9th FENS Forum of Neuroscience. Milan. 05.-09.07.2014.
Periasamy, R; Fuchs, AL; Seiler, Stefanie; Widmer, Hans Rudolf; Di Santo, Stefano (January 2014). Soluble factors derived from endothelial progenitors promote brain microvascular cell viability. In: Annual Meeting of the Swiss Society for Neuroscience. Bern. 24.-25.01.2014.
Seiler, Stefanie; Polloni, D; Widmer, Hans Rudolf; Di Santo, Stefano (January 2014). Effects of Nogo-receptor 1 antagonization in combination with Creatine or GDNF administration on cultured dopaminergic neurons (Unpublished). In: Annual Meeting of the Department of Clinical Research. Bern. 24.-25.01.2014.
Pollini, D; Seiler, Stefanie; Di Santo, Stefano; Widmer, Hans Rudolf (January 2014). Assessment of new strategies to improve yield of dopaminergic neurons in vitro: Effects of Nogo-receptor 1 antagonization and NT4/5 administration (Unpublished). In: Annual Meeting of the Swiss Society for Neuroscience. Bern. 24.-25.01.2014.
Henzi, A; Seiler, Stefanie; Porz, Nicole; Widmer, Hans Rudolf; Di Santo, Stefano (2014). Paracrine factors promote neurogenesis in the adult rat brain (Unpublished). In: Annual Meeting of the Swiss Society for Neuroscience. Bern. 24.-25.01.2014.
Seiler, Stefanie; Pollini, D; Di Santo, Stefano; Widmer, Hans Rudolf (2014). Effects of antagonizing Nogo-1 receptor on survival and morphological differentiation of dopaminergic neurons in mesencephalic cultures (Unpublished). In: Annual Meeting of the Swiss Society for Neuroscience. Bern. 24.-25.01.2014.
Periasamy, R; Fuchs, AL; Seiler, Stefanie; Widmer, Hans Rudolf; Di Santo, Stefano (2014). Endothelial progenitors derived soluble factors promote brain microvascular cell viability. In: FENS Meeting. Mailand. 05.07.-09.07.2014.
Periasamy, R; Fuchs, AL; Seiler, Stefanie; Widmer, Hans Rudolf; Di Santo, Stefano (2014). Identification of factors involved in the actions of endothelial progenitor cells-derived conditioned medium on brain microvascular cells. In: 10th Annual Meeting Swiss Stem Cell Network. Geneva. 04.07.2014.
Fontana, Chiara; Seiler, Stefanie; Widmer, Hans Rudolf; Di Santo, Stefano (2014). Immunolocalization of Angiogenein in rat CNS (Unpublished). In: Annual Meeting of the Department of Clinical Research. Bern.
Henzi, A; Seiler, Stefanie; Porz, Nicole; Widmer, Hans Rudolf; Di Santo, Stefano (2014). Increased neural precursor cell in the adult rat brain by infusion of endothelial progenitor cells secretome (Unpublished). In: Annual Meeting of the Department of Clinical Research. Bern.
Fuchs, A; Periasamy, R; Seiler, Stefanie; Sahli, S; Widmer, Hans Rudolf; Di Santo, Stefano (2014). Characterization of the angiogenic properties of endothelial progenitor cells derived secretome (Unpublished). In: Annual Meeting of the Department of Clinical Research. Bern.
Sahli, S; Seiler, Stefanie; Di Santo, Stefano; Widmer, Hans Rudolf (2014). Increased yield of dopaminergic neurons by chronic minocycline treatment and HIF-1 alpha stabilization. In: Annual Meeting of the Swiss Society for Neuroscience. Bern. 24.01.-25.01.2014.
Di Santo, Stefano; Seiler, Stefanie; Periasamy, R; Fuchs, AL; Sahli, S; Widmer, Hans Rudolf (2014). The secretome of Endothelial Progenitor Cells supports microvasculaer cells viability. In: Annual Meeting NECTAR. Galway. 27.11.-28.11.2014.
Periasamy, R; Fuchs, AL; Seiler, Stefanie; Widmer, Hans Rudolf; Di Santo, Stefano (2014). Analysis of the effects of conditioned medium from endothelial progenitors on brain microvascular cells (Unpublished). In: Annual ASNTR Meeting. Clearwater.
Seiler, Stefanie; Pollini, Dario; Di Santo, Stefano; Widmer, Hans Rudolf (September 2013). Antagonizing Nogo-receptor 1 promotes the number of cultured dopaminergic neurons and elongates their neurites. In: 12th International Symposium on Neural Transplantation & Restoration. Cardiff. 03.-06.09.2013.
Di Santo, Stefano; Seiler, Stefanie; Widmer, Hans Rudolf (September 2013). Differential neuroprotective capacity of Endothelial progenitor Cells-derived factors. In: 12th International Symposium on Neural Transplantation & Restoration. Cardiff. 03.-06.09.2013.
Henzi, Anna; Porz, Nicole; Widmer, Hans Rudolf; Di Santo, Stefano (2013). EPC secretome promotes neurogenesis in rat brain: New tool for brain repair? In: Annual Meeting of the Department of Clinical Research. Bern.
Nesti, Cédric; Seiler, Stefanie; Widmer, Hans Rudolf; Di Santo, Stefano; Andres, Robert (2013). Effect of hemorrhage on neuronal progenitor cells in vitro. In: Annual Meeting of the Department of Clinical Research. Bern.
Fontana, Chiara; Seiler, Stefanie; Widmer, Hans Rudolf; Di Santo, Stefano (2013). The angiogenic Rnase angiogenin is expressed by neurons in rat CNS. In: Annual Meeting of the Department of Clinical Research. Bern.
Seiler, Stefanie; Pollini, Dario; Di Santo, Stefano; Widmer, Hans Rudolf (2013). Increased dopaminergic cell number and neurite length by antagonizing Nogo-1 receptor. In: Annual Meeting of the Department of Clinical Research. Bern.
Di Santo, Stefano; Seiler, Stefanie; Widmer, Hans Rudolf (2013). Neuroprotective properties of EPC-derived soluble factors. In: Annual Meeting of the Department of Clinical Research. Bern.
Di Santo, Stefano; Bähler, S.; Ducray, Angélique; Raabe, Andreas; Wallimann, T.; Widmer, Hans Rudolf (2010). Different expression pattern of the creatine transporter and guanidinoacetate methyltransferase between adult rat forbrain and spinal cord cholinergic neurons. In: SSN Meeting. Lausanne.
