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Duthaler, Urs; Bachmann, Fabio; Suenderhauf, Claudia; Grandinetti, Tanja; Pfefferkorn, Florian; Haschke, Manuel; Hruz, Petr; Bouitbir, Jamal; Krähenbühl, Stephan (2022). Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail Differently. Clinical pharmacokinetics, 61(7), pp. 1039-1055. Springer 10.1007/s40262-022-01119-0
Bachmann, Fabio; Duthaler, Urs; Meyer Zu Schwabedissen, Henriette E; Puchkov, Maxim; Huwyler, Jörg; Haschke, Manuel; Krähenbühl, Stephan (2021). Metamizole is a moderate cytochrome P450 inducer via the constitutive androstane receptor and a weak inhibitor of CYP1A2. Clinical pharmacology and therapeutics, 109(6), pp. 1505-1516. Wiley 10.1002/cpt.2141
Bachmann, Fabio; Blaser, Lea; Haschke, Manuel Martin; Krähenbühl, Stephan; Duthaler, Urs (2020). Development and validation of an LC-MS/MS method for the bioanalysis of the major metamizole metabolites in human plasma. Bioanalysis, 12(3), pp. 175-189. Future Science 10.4155/bio-2019-0251
Ziesenitz, Victoria C; Rodieux, Frédérique; Atkinson, Andrew; Borter, Carole; Bielicki, Julia A; Haschke, Manuel; Duthaler, Urs; Bachmann, Fabio; Erb, Thomas O; Gürtler, Nicolas; Holland-Cunz, Stefan; van den Anker, Johannes N; Gotta, Verena; Pfister, Marc (2019). Dose evaluation of intravenous metamizole (dipyrone) in infants and children: a prospective population pharmacokinetic study. European journal of clinical pharmacology, 75(11), pp. 1491-1502. Springer 10.1007/s00228-019-02720-2
Rudin, Deborah; Lanzilotto, Angelo; Bachmann, Fabio; Housecroft, Catherine E; Constable, Edwin C; Drewe, Jürgen; Haschke, Manuel Martin; Krähenbühl, Stephan (2019). Non-immunological toxicological mechanisms of metamizole-associated neutropenia in HL60 cells. Biochemical pharmacology, 163, pp. 345-356. Elsevier 10.1016/j.bcp.2019.01.011
Bachmann, Fabio; Duthaler, Urs; Rudin, Deborah; Krähenbühl, Stephan; Haschke, Manuel Martin (2018). N-demethylation of N-methyl-4-aminoantipyrine, the main metabolite of metamizole. European journal of pharmaceutical sciences, 120, pp. 172-180. Elsevier 10.1016/j.ejps.2018.05.003
Berger, Benjamin; Bachmann, Fabio; Duthaler, Urs; Krähenbühl, Stephan; Haschke, Manuel Martin (2018). Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug. Frontiers in Pharmacology, 9(774), p. 774. Frontiers 10.3389/fphar.2018.00774
