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Papachristodoulou, Alexandros; Heidegger, Isabel; Virk, Renu K; Di Bernardo, Matteo; Kim, Jaime Y; Laplaca, Caroline; Picech, Florencia; Schäfer, Georg; De Castro, Guarionex Joel; Hibshoosh, Hanina; Loda, Massimo; Klocker, Helmut; Rubin, Mark A; Zheng, Tian; Benson, Mitchell C; McKiernan, James M; Dutta, Aditya; Abate-Shen, Cory (2024). Metformin Overcomes the Consequences of NKX3.1 Loss to Suppress Prostate Cancer Progression. European urology, 85(4), pp. 361-372. Elsevier 10.1016/j.eururo.2023.07.016
Augspach, Anke; Rubin, Mark A (2024). Upcycling HOXB13: enhancing prostate cancer detection with a novel antibody†. The journal of pathology: clinical research, 262(4), pp. 391-394. Wiley 10.1002/path.6258
Akhoundova, Dilara; Francica, Paola; Rottenberg, Sven; Rubin, Mark A (2024). DNA Damage Response and Mismatch Repair Gene Defects in Advanced and Metastatic Prostate Cancer. Advances in anatomic pathology, 31(2), pp. 61-69. Lippincott Williams & Wilkins 10.1097/PAP.0000000000000422
Akhoundova, Dilara; Rubin, Mark Andrew (2024). The grand challenge of moving cancer whole-genome sequencing into the clinic. Nature medicine, 30(1), pp. 39-40. Nature Publishing Group 10.1038/s41591-023-02697-7
Bratic Hench, Ivana; Roma, Luca; Conticelli, Floriana; Bubendorf, Lenard; Calgua, Byron; Le Magnen, Clémentine; Piscuoglio, Salvatore; Rubin, Mark A; Chirindel, Alin; Nicolas, Guillaume P; Vlajnic, Tatjana; Zellweger, Tobias; Templeton, Arnoud J; Stenner, Frank; Ruiz, Christian; Rentsch, Cyrill; Bubendorf, Lukas (2024). Cell-Free DNA Genomic Profiling and Its Clinical Implementation in Advanced Prostate Cancer. Cancers, 16(1) MDPI AG 10.3390/cancers16010045
Van Emmenis, Lucie; Ku, Sheng-Yu; Gayvert, Kaitlyn; Branch, Jonathan R; Brady, Nicholas J; Basu, Subhasree; Russell, Michael; Cyrta, Joanna; Vosoughi, Aram; Sailer, Verena; Alnajar, Hussein; Dardenne, Etienne; Koumis, Elena; Puca, Loredana; Robinson, Brian D; Feldkamp, Michael D; Winkis, Annmarie; Majewski, Nathan; Rupnow, Brent; Gottardis, Marco M; ... (2023). The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer. Cancer research communications, 3(8), pp. 1447-1459. American Association for Cancer Research 10.1158/2767-9764.CRC-22-0491
Li, Jia J; Vasciaveo, Alessandro; Karagiannis, Dimitrios; Sun, Zhen; Chen, Xiao; Socciarelli, Fabio; Frankenstein, Ziv; Zou, Min; Pannellini, Tania; Chen, Yu; Gardner, Kevin; Robinson, Brian D; de Bono, Johann; Abate-Shen, Cory; Rubin, Mark A.; Loda, Massimo; Sawyers, Charles L; Califano, Andrea; Lu, Chao and Shen, Michael M (19 July 2023). NSD2 maintains lineage plasticity and castration-resistance in neuroendocrine prostate cancer. (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2023.07.18.549585
Augspach, Anke Katharina; Drake, Kyle D; Roma, Luca; Qian, Ellen; Lee, Se Ri; Clarke, Declan; Kumar, Sushant; Jaquet, Muriel; Gallon, John; Bolis, Marco; Triscott, Joanna Catherine Caprio; Galván, José A; Chen, Yu; Thalmann, George N; Kruithof-de Julio, Marianna; Theurillat, Jean-Philippe P; Wuchty, Stefan; Gerstein, Mark; Piscuoglio, Salvatore; Kanadia, Rahul N; ... (2023). Minor intron splicing is critical for survival of lethal prostate cancer. Molecular cell, 83(12), 1983-2002.e11. Cell Press 10.1016/j.molcel.2023.05.017
Gillessen, Silke; Bossi, Alberto; Davis, Ian D; de Bono, Johann; Fizazi, Karim; James, Nicholas D; Mottet, Nicolas; Shore, Neal; Small, Eric; Smith, Matthew; Sweeney, Christopher J; Tombal, Bertrand; Antonarakis, Emmanuel S; Aparicio, Ana M; Armstrong, Andrew J; Attard, Gerhardt; Beer, Tomasz M; Beltran, Himisha; Bjartell, Anders; Blanchard, Pierre; ... (2023). Management of patients with advanced prostate cancer-metastatic and/or castration-resistant prostate cancer: Report of the Advanced Prostate Cancer Consensus Conference (APCCC) 2022. European journal of cancer, 185, pp. 178-215. Elsevier 10.1016/j.ejca.2023.02.018
Gallon, John; Rodríguez-Calero, Antonio; Benjak, Andrej; Akhoundova, Dilara; Maletti, Sina; Amstutz, Ursula; Hewer, Ekkehard; Genitsch, Vera; Fleischmann, Achim; Rushing, Elisabeth J; Grobholz, Rainer; Fischer, Ingeborg; Jochum, Wolfram; Cathomas, Gieri; Osunkoya, Adeboye O; Bubendorf, Lukas; Moch, Holger; Thalmann, George; Feng, Felix Y; Gillessen, Silke; ... (2023). DNA methylation landscapes of prostate cancer brain metastasis are shaped by early driver genetic alterations. Cancer research, 83(8), pp. 1203-1213. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-22-2236
Planas-Paz, Lara; Pliego-Mendieta, Alicia; Hagedorn, Catherine; Aguilera-Garcia, Domingo; Haberecker, Martina; Arnold, Fabian; Herzog, Marius; Bankel, Lorenz; Guggenberger, Roman; Steiner, Sabrina; Chen, Yanjiang; Kahraman, Abdullah; Zoche, Martin; Rubin, Mark A; Moch, Holger; Britschgi, Christian; Pauli, Chantal (2023). Unravelling homologous recombination repair deficiency and therapeutic opportunities in soft tissue and bone sarcoma. EMBO molecular medicine, 15(4), e16863. EMBO Press 10.15252/emmm.202216863
Kashani, Elham; Schnidrig, Désirée; Hashemi Gheinani, Ali; Ninck, Martina Selina; Zens, Philipp; Maragkou, Theoni; Baumgartner, Ulrich; Schucht, Philippe; Rätsch, Gunnar; Rubin, Mark A; Berezowska, Sabina; Ng, Charlotte K Y; Vassella, Erik (2023). Integrated longitudinal analysis of adult grade 4 diffuse gliomas with long-term relapse interval revealed upregulation of TGF-β signaling in recurrent tumors. Neuro-Oncology, 25(4), pp. 662-673. Oxford University Press 10.1093/neuonc/noac220
Netto, George J; Amin, Mahul B; Compérat, Eva M; Gill, Anthony J; Hartmann, Arndt; Moch, Holger; Menon, Santosh; Raspollini, Maria R; Rubin, Mark A; Srigley, John R; Hoon Tan, Puay; Tickoo, Satish K; Tsuzuki, Toyonori; Turajlic, Samra; Cree, Ian; Berney, Daniel M (2023). Prostate Adenocarcinoma Grade Group 1: Rationale for Retaining a Cancer Label in the 2022 World Health Organization Classification. European urology, 83(4), pp. 301-303. Elsevier 10.1016/j.eururo.2022.09.015
Li, Ziyi; Huang, Yijian; Patil, Dattatraya; Rubin, Mark; Sanda, Martin G (2023). Covariate-specific evaluation of continuous biomarker. Statistics in medicine, 42(7), pp. 953-969. Wiley 10.1002/sim.9652
Menon, S; Moch, H; Berney, D M; Cree, I A; Srigley, J R; Tsuzuki, T; Compérat, E; Hartmann, A; Netto, G; Rubin, Mark A; Gill, A J; Turajlic, S; Tan, P H; Raspollini, M R; Tickoo, S K; Amin, M B (2023). The WHO 2022 classification of penile and scrotal cancers: updates and evolution. Histopathology, 82(4), pp. 508-520. Wiley 10.1111/his.14824
Schnidrig, Desiree; Garofoli, Andrea; Benjak, Andrej; Rätsch, Gunnar; Rubin, Mark A; Piscuoglio, Salvatore; Ng, Charlotte K Y (2023). PipeIT2: A tumor-only somatic variant calling workflow for molecular diagnostic ion torrent sequencing data. Genomics, 115(2), p. 110587. Elsevier 10.1016/j.ygeno.2023.110587
Gillessen, Silke; Bossi, Alberto; Davis, Ian D; de Bono, Johann; Fizazi, Karim; James, Nicholas D; Mottet, Nicolas; Shore, Neal; Small, Eric; Smith, Mathew; Sweeney, Christopher; Tombal, Bertrand; Antonarakis, Emmanuel S; Aparicio, Ana M; Armstrong, Andrew J; Attard, Gerhardt; Beer, Tomasz M; Beltran, Himisha; Bjartell, Anders; Blanchard, Pierre; ... (2023). Management of Patients with Advanced Prostate Cancer. Part I: Intermediate-/High-risk and Locally Advanced Disease, Biochemical Relapse, and Side Effects of Hormonal Treatment: Report of the Advanced Prostate Cancer Consensus Conference 2022. European urology, 83(3), pp. 267-293. Elsevier 10.1016/j.eururo.2022.11.002
Vasciaveo, Alessandro; Arriaga, Juan Martin; Nunes de Almeida, Francisca; Zou, Min; Douglass, Eugene F; Picech, Florencia; Shibata, Maho; Rodriguez-Calero, Antonio; de Brot, Simone; Mitrofanova, Antonina; Chua, Chee Wai; Karan, Charles; Realubit, Ronald; Pampou, Sergey; Kim, Jaime Y; Afari, Stephanie N; Mukhammadov, Timur; Zanella, Luca; Corey, Eva; Alvarez, Mariano J; ... (2023). OncoLoop: A network-based precision cancer medicine framework. Cancer discovery, 13(2), pp. 386-409. American Association for Cancer Research 10.1158/2159-8290.CD-22-0342
Triscott, Joanna; Reist, Matthias; Küng, Lukas; Moselle, Francielle C; Lehner, Marika; Gallon, John; Ravi, Archna; Arora, Gurpreet K; De Brot, Simone; Lundquist, Mark; Gallart-Ayala, Hector; Ivanisevic, Julijana; Piscuoglio, Salvatore; Cantley, Lewis C; Emerling, Brooke M; Rubin, Mark A (2023). PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition. Science Advances, 9(5), eade8641. American Association for the Advancement of Science 10.1126/sciadv.ade8641
Rheinbay, Esther; Nielsen, Morten Muhlig; Abascal, Federico; Wala, Jeremiah A; Shapira, Ofer; Tiao, Grace; Hornshøj, Henrik; Hess, Julian M; Juul, Randi Istrup; Lin, Ziao; Feuerbach, Lars; Sabarinathan, Radhakrishnan; Madsen, Tobias; Kim, Jaegil; Mularoni, Loris; Shuai, Shimin; Lanzos, Andrés; Herrmann, Carl; Maruvka, Yosef E; Shen, Ciyue; ... (2023). Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. Nature, 614(7948), E40. Springer Nature 10.1038/s41586-022-05599-9
Casolino, Raffaella; Johns, Amber L; Courtot, Melanie; Lawlor, Rita T; De Lorenzo, Francesco; Horgan, Denis; Mateo, Joaquin; Normanno, Nicola; Rubin, Mark; Stein, Lincoln; Subbiah, Vivek; Westphalen, Benedikt C; Lawler, Mark; Park, Keunchil; Perdomo, Sandra; Yoshino, Takayuki; Wu, Jianmin; Biankin, Andrew V (2023). Accelerating cancer omics and precision oncology in health care and research: a Lancet Oncology Commission. The lancet oncology, 24(2), pp. 123-125. Elsevier 10.1016/S1470-2045(23)00007-4
Rubin, Mark A; Amin, Mahul B; Compérat, Eva; Gill, Anthony; Hartman, Arndt; Menon, Santosh; Raspollini, Maria; Srigley, John; Tan, Puay Hoon; Ticktoo, Satish; Tsuzuki, Toyonori; Turajlic, Samra; Cree, Ian; Berney, Daniel; Moch, Holger; Netto, George J (2023). Reply to Yongbao Wei, Haijian Huang, and Liefu Ye's Letter to the Editor re: George J. Netto, Mahul B. Amin, Daniel M. Berney, et al. The 2022 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs-Part B: Prostate and Urinary Tract Tumors. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2022.07.002. European urology, 83(1), e16-e17. Elsevier 10.1016/j.eururo.2022.09.021
Cyrta, Joanna; Rosiene, Joel; Bareja, Rohan; Kudman, Sarah; Al Zoughbi, Wael; Motanagh, Samaneh; Wilkes, David C.; Eng, Kenneth; Zhang, Tuo; Sticca, Evan; Mathew, Susan; Rubin, Mark A.; Imielinksi, Marcin; Mosquera, Juan Miguel (2022). Whole-genome characterization of myoepithelial carcinomas of the soft tissue. Cold Spring Harbor molecular case studies, 8(7) Cold Spring Harbor Laboratory Press 10.1101/mcs.a006227
Akhoundova, Dilara; Feng, Felix Y; Pritchard, Colin C; Rubin, Mark A (2022). Molecular Genetics of Prostate Cancer and Role of Genomic Testing. Surgical pathology clinics, 15(4), pp. 617-628. 10.1016/j.path.2022.08.002
Zeng, Qiqun; Saghafinia, Sadegh; Chryplewicz, Agnieszka; Fournier, Nadine; Christe, Lucine; Xie, Yu-Qing; Guillot, Jeremy; Yucel, Simge; Li, Pumin; Galván, José A; Karamitopoulou, Eva; Zlobec, Inti; Ataca, Dalya; Gallean, Fleuriane; Zhang, Peng; Rodríguez-Calero, José Antonio; Rubin, Mark; Tichet, Mélanie; Homicsko, Krisztian and Hanahan, Douglas (2022). Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion. Science, 378(6621), eabl7207. American Association for the Advancement of Science 10.1126/science.abl7207
Ferguson, Alison M; Rubin, Mark A (2022). Lineage plasticity in prostate cancer: Looking beyond intrinsic alterations. Cancer letters, 548(215901), p. 215901. Elsevier 10.1016/j.canlet.2022.215901
Moch, Holger; Amin, Mahul B; Berney, Daniel M; Compérat, Eva M; Gill, Anthony J; Hartmann, Arndt; Menon, Santosh; Raspollini, Maria R; Rubin, Mark A; Srigley, John R; Hoon Tan, Puay; Tickoo, Satish K; Tsuzuki, Toyonori; Turajlic, Samra; Cree, Ian; Netto, George J (2022). The 2022 World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours. European urology, 82(5), pp. 458-468. Elsevier 10.1016/j.eururo.2022.06.016
Netto, George J; Amin, Mahul B; Berney, Daniel M; Compérat, Eva M; Gill, Anthony J; Hartmann, Arndt; Menon, Santosh; Raspollini, Maria R; Rubin, Mark A; Srigley, John R; Hoon Tan, Puay; Tickoo, Satish K; Tsuzuki, Toyonori; Turajlic, Samra; Cree, Ian; Moch, Holger (2022). The 2022 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs-Part B: Prostate and Urinary Tract Tumors. European urology, 82(5), pp. 469-482. Elsevier 10.1016/j.eururo.2022.07.002
Berney, D M; Cree, I; Rao, V; Moch, H; Srigley, J R; Tsuzuki, T; Amin, M B; Comperat, E M; Hartmann, A; Menon, S; Netto, G J; Rubin, M A; Turajlic, S; Raspollini, M R; Tickoo, S K (2022). An Introduction to the WHO 5th Edition 2022 Classification of Testicular tumours. Histopathology, 81(4), pp. 459-466. Wiley 10.1111/his.14675
Lobo, João; Ohashi, Riuko; Amin, Mahul B; Berney, Daniel M; Compérat, Eva M; Cree, Ian A; Gill, Anthony J; Hartmann, Arndt; Menon, Santosh; Netto, George J; Raspollini, Maria R; Rubin, Mark A; Tan, Puay Hoon; Tickoo, Satish K; Tsuzuki, Toyonori; Turajlic, Samra; Zhou, Ming; Srigley, John R; Moch, Holger (2022). The WHO 2022 landscape of papillary and chromophobe renal cell carcinoma. Histopathology, 81(4), pp. 426-438. Wiley 10.1111/his.14700
Janowczyk, Andrew; Baumhoer, Daniel; Dirnhofer, Stefan; Grobholz, Rainer; Kipar, Anja; de Leval, Laurence; Merkler, Doron; Michielin, Olivier; Moch, Holger; Perren, Aurel; Rottenberg, Sven; Rubbia-Brandt, Laura; Rubin, Mark A; Sempoux, Christine; Tolnay, Markus; Zlobec, Inti; Koelzer, Viktor Hendrik (2022). Towards a national strategy for digital pathology in Switzerland. Virchows Archiv, 481(4), pp. 647-652. Springer 10.1007/s00428-022-03345-0
Kench, James G; Amin, Mahul B; Berney, Daniel M; Compérat, Eva M; Cree, Ian A; Gill, Anthony J; Hartmann, Arndt; Menon, Santosh; Moch, Holger; Netto, George J; Raspollini, Maria R; Rubin, Mark A; Tan, Puay Hoon; Tsuzuki, Toyonori; Turjalic, Samra; van der Kwast, Theo H; Zhou, Ming; Srigley, John R (2022). WHO Classification of Tumours 5th Edition: Evolving Issues in Classification, Diagnosis and Prognostication of Prostate Cancer. Histopathology, 81(4), pp. 447-458. Wiley 10.1111/his.14711
Compérat, Eva; Amin, Mahul B; Berney, Dan M; Cree, Ian; Menon, Santosh; Moch, Holger; Netto, George J; Rao, Vishal; Raspollini, Maria Rosaria; Rubin, Mark A; Srigley, John R; Tan, Puay Hoon; Tickoo, Satish Kumar; Turajlic, Samra; Tsuzuki, Toyonori (2022). What's new in WHO fifth edition - urinary tract. Histopathology, 81(4), pp. 439-446. Wiley 10.1111/his.14764
Akhoundova, Dilara; Rubin, Mark A (2022). Clinical application of advanced multi-omics tumor profiling: Shaping precision oncology of the future. Cancer cell, 40(9), pp. 920-938. Cell Press 10.1016/j.ccell.2022.08.011
Cotter, Kellie; Rubin, Mark A (2022). The evolving landscape of prostate cancer somatic mutations. The Prostate, 82 Suppl 1(Suppl 1), S13-S24. Wiley 10.1002/pros.24353
Cyrta, Joanna; Prandi, Davide; Arora, Arshi; Hovelson, Daniel H; Sboner, Andrea; Rodriguez, Antonio; Fedrizzi, Tarcisio; Beltran, Himisha; Robinson, Dan R; Gopalan, Anurandha; True, Lawrence; Nelson, Peter S; Robinson, Brian D; Mosquera, Juan Miguel; Tomlins, Scott A; Shen, Ronglai; Demichelis, Francesca; Rubin, Mark A (2022). Comparative genomics of primary prostate cancer and paired metastases: insights from 12 molecular case studies. The journal of pathology, 257(3), pp. 274-284. Wiley 10.1002/path.5887
Turco, Fabio; Armstrong, Andrew; Attard, Gerhardt; Beer, Tomasz M; Beltran, Himisha; Bjartell, Anders; Bossi, Alberto; Briganti, Alberto; Bristow, Rob G; Bulbul, Muhammad; Caffo, Orazio; Chi, Kim N; Clarke, Caroline S; Clarke, Noel; Davis, Ian D; de Bono, Johann; Duran, Ignacio; Eeles, Ros; Efstathiou, Eleni; Efstathiou, Jason; ... (2022). What Experts Think About Prostate Cancer Management During the COVID-19 Pandemic: Report from the Advanced Prostate Cancer Consensus Conference 2021. European urology, 82(1), pp. 6-11. Elsevier 10.1016/j.eururo.2022.02.010
Turco, Fabio; Armstrong, Andrew; Attard, Gerhardt; Beer, Tomasz M; Beltran, Himisha; Bjartell, Anders; Bossi, Alberto; Briganti, Alberto; Bristow, Rob G; Bulbul, Muhammad; Caffo, Orazio; Chi, Kim N; Clarke, Caroline; Clarke, Noel; Davis, Ian D; de Bono, Johann; Duran, Ignacio; Eeles, Ros; Efstathiou, Eleni; Efstathiou, Jason; ... (2022). Corrigendum to "What Experts Think About Prostate Cancer Management During the COVID-19 Pandemic: Report from the Advanced Prostate Cancer Consensus Conference 2021" [Eur Urol 2022]. European urology, 82(1), e18-e19. Elsevier 10.1016/j.eururo.2022.04.004
Raman, Renuka; Villefranc, Jacques A; Ullmann, Timothy M; Thiesmeyer, Jessica; Anelli, Viviana; Yao, Jun; Hurley, James R; Pauli, Chantal; Bareja, Rohan; Wha Eng, Kenneth; Dorsaint, Princesca; Wilkes, David C; Beg, Shaham; Kudman, Sarah; Shaw, Reid; Churchill, Michael; Ahmed, Adnan; Keefer, Laurel; Misner, Ian; Nichol, Donna; ... (2022). Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer. Journal of experimental medicine, 219(6) Rockefeller University Press 10.1084/jem.20210390
Orlando, Francesco; Romanel, Alessandro; Trujillo, Blanca; Sigouros, Michael; Wetterskog, Daniel; Quaini, Orsetta; Leone, Gianmarco; Xiang, Jenny Z; Wingate, Anna; Tagawa, Scott; Jayaram, Anuradha; Linch, Mark; Jamal-Hanjani, Mariam; Swanton, Charles; Rubin, Mark A; Wyatt, Alexander W; Beltran, Himisha; Attard, Gerhardt; Demichelis, Francesca (2022). Allele-informed copy number evaluation of plasma DNA samples from metastatic prostate cancer patients: the PCF_SELECT consortium assay. NAR cancer, 4(2), zcac016. Oxford University Press 10.1093/narcan/zcac016
Rodriguez-Calero, Antonio; Gallon, John; Akhoundova, Dilara; Maletti, Sina; Ferguson, Alison; Cyrta, Joanna; Amstutz, Ursula; Garofoli, Andrea; Paradiso, Viola; Tomlins, Scott A; Hewer, Ekkehard; Genitsch, Vera; Fleischmann, Achim; Vassella, Erik; Rushing, Elisabeth J; Grobholz, Rainer; Fischer, Ingeborg; Jochum, Wolfram; Cathomas, Gieri; Osunkoya, Adeboye O; ... (2022). Alterations in homologous recombination repair genes in prostate cancer brain metastases. Nature Communications, 13(1), p. 2400. Springer Nature 10.1038/s41467-022-30003-5
de Brot, Simone; Lothion-Roy, Jennifer; Grau-Roma, Llorenç; White, Emily; Guscetti, Franco; Rubin, Mark A.; Mongan, Nigel P (2022). Histological and immunohistochemical investigation of canine prostate carcinoma with identification of common intraductal carcinoma component. Veterinary and comparative oncology, 20(1), pp. 38-49. Wiley 10.1111/vco.12704
Fontugne, Jacqueline; Cai, Peter Y; Alnajar, Hussein; Bhinder, Bhavneet; Park, Kyung; Ye, Huihui; Beg, Shaham; Sailer, Verena; Siddiqui, Javed; Blattner-Johnson, Mirjam; Croyle, Jaclyn A; Noorzad, Zohal; Calagua, Carla; MacDonald, Theresa Y; Axcrona, Ulrika; Bogaard, Mari; Axcrona, Karol; Scherr, Douglas S; Sanda, Martin G; Johannessen, Bjarne; ... (2022). Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci. JCI insight, 7(4) JCI Insight 10.1172/jci.insight.155309
Pauli, Chantal; De Boni, Lamberto; Pauwels, Jonathan E; Chen, Yanjiang; Planas-Paz, Lara; Shaw, Reid; Emerling, Brooke M; Grandori, Carla; Hopkins, Benjamin D; Rubin, Mark A (2022). A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients. Molecular cancer research, 20(2), pp. 244-252. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-21-0255
Ryman-Tubb, Toby; Lothion-Roy, Jennifer H; Metzler, Veronika M; Harris, Anna E; Robinson, Brian D; Rizvanov, Albert A; Jeyapalan, Jennie N; James, Victoria H; England, Gary; Rutland, Catrin S; Persson, Jenny L; Kenner, Lukas; Rubin, Mark A; Mongan, Nigel P; de Brot, Simone (2022). Comparative pathology of dog and human prostate cancer. Veterinary medicine and science, 8(1), pp. 110-120. Wiley 10.1002/vms3.642
Vogl, Ursula M.; Beer, Tomasz M.; Davis, Ian D.; Shore, Neal D.; Sweeney, Christopher J.; Ost, Piet; Attard, Gerhardt; Bossi, Alberto; de Bono, Johann; Drake, Charles G.; Efstathiou, Eleni; Fanti, Stefano; Fizazi, Karim; Halabi, Susan; James, Nicolas; Mottet, Nicolas; Padhani, Anwar R.; Roach, Mack; Rubin, Mark; Sartor, Oliver; ... (2022). Lack of consensus identifies important areas for future clinical research: Advanced Prostate Cancer Consensus Conference (APCCC) 2019 findings. European journal of cancer, 160, pp. 24-60. Elsevier 10.1016/j.ejca.2021.09.036
Bolis, Marco; Bossi, Daniela; Vallerga, Arianna; Ceserani, Valentina; Cavalli, Manuela; Impellizzieri, Daniela; Di Rito, Laura; Zoni, Eugenio; Mosole, Simone; Elia, Angela Rita; Rinaldi, Andrea; Pereira Mestre, Ricardo; D'Antonio, Eugenia; Ferrari, Matteo; Stoffel, Flavio; Jermini, Fernando; Gillessen, Silke; Bubendorf, Lukas; Schraml, Peter; Calcinotto, Arianna; ... (2021). Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression. Nature Communications, 12(1), p. 7033. Springer Nature 10.1038/s41467-021-26840-5
Mukhopadhyay, Chandrani; Yang, Chenyi; Xu, Limei; Liu, Deli; Wang, Yu; Huang, Dennis; Deonarine, Lesa Dayal; Cyrta, Joanna; Davicioni, Elai; Sboner, Andrea; Robinson, Brian D; Chinnaiyan, Arul M; Rubin, Mark A; Barbieri, Christopher E; Zhou, Pengbo (2021). G3BP1 inhibits Cul3SPOP to amplify AR signaling and promote prostate cancer. Nature Communications, 12(1), p. 6662. Springer Nature 10.1038/s41467-021-27024-x
Armstrong, Andrew J; Li, Xiaotong; Tucker, Matthew; Li, Shantao; Mu, Xinmeng Jasmine; Eng, Kenneth Wha; Sboner, Andrea; Rubin, Mark; Gerstein, Mark (2021). Molecular medicine tumor board: whole-genome sequencing to inform on personalized medicine for a man with advanced prostate cancer. Prostate cancer and prostatic diseases, 24(3), pp. 786-793. Springer Nature 10.1038/s41391-021-00324-5
El Tekle, Geniver; Bernasocchi, Tiziano; Unni, Arun M; Bertoni, Francesco; Rossi, Davide; Rubin, Mark A.; Theurillat, Jean-Philippe (2021). Co-occurrence and mutual exclusivity: what cross-cancer mutation patterns can tell us. Trends in cancer, 7(9), pp. 823-836. Elsevier 10.1016/j.trecan.2021.04.009
Papachristodoulou, Alexandros; Rodríguez-Calero, Antonio; Panja, Sukanya; Margolskee, Elizabeth; Virk, Renu K; Milner, Teresa A; Martina, Luis Pina; Kim, Jaime Y; Di Bernardo, Matteo; Williams, Alanna B; Maliza, Elvis A; Caputo, Joseph M; Haas, Christopher; Wang, Vinson; De Castro, Guarionex Joel; Wenske, Sven; Hibshoosh, Hanina; McKiernan, James M; Shen, Michael M; Rubin, Mark A; ... (2021). NKX3.1 Localization to Mitochondria Suppresses Prostate Cancer Initiation. Cancer discovery, 11(9), pp. 2316-2333. American Association for Cancer Research 10.1158/2159-8290.CD-20-1765
Cotter, Kellie A; Gallon, John; Uebersax, Nadine; Rubin, Philip; Meyer, Kate D; Piscuoglio, Salvatore; Jaffrey, Samie R; Rubin, Mark A (2021). Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-Low Induction of Therapy Resistance. Molecular cancer research, 19(8), pp. 1398-1411. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-21-0014
Servant, Raphaëlle; Garioni, Michele; Vlajnic, Tatjana; Blind, Melanie; Pueschel, Heike; Müller, David C; Zellweger, Tobias; Templeton, Arnoud J; Garofoli, Andrea; Maletti, Sina Laura; Piscuoglio, Salvatore; Rubin, Mark A.; Seifert, Helge; Rentsch, Cyrill A; Bubendorf, Lukas; Le Magnen, Clémentine (2021). Prostate cancer patient-derived organoids: detailed outcome from a prospective cohort of 81 clinical specimens. The journal of pathology, 254(5), pp. 543-555. Wiley 10.1002/path.5698
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Formaggio, Nicolò; Rubin, Mark A.; Theurillat, Jean-Philippe (2021). Loss and revival of androgen receptor signaling in advanced prostate cancer. Oncogene, 40(7), pp. 1205-1216. Springer Nature 10.1038/s41388-020-01598-0
Rubin, Mark A.; Bristow, Robert G; Thienger, Phillip D.; Dive, Caroline; Imielinski, Marcin (2020). Impact of Lineage Plasticity to and from a Neuroendocrine Phenotype on Progression and Response in Prostate and Lung Cancers. Molecular cell, 80(4), pp. 562-577. Cell Press 10.1016/j.molcel.2020.10.033
Cyrta, Joanna; Augspach, Anke; De Filippo, Maria Rosaria; Prandi, Davide; Thienger, Phillip; Benelli, Matteo; Cooley, Victoria; Bareja, Rohan; Wilkes, David; Chae, Sung-Suk; Cavaliere, Paola; Dephoure, Noah; Uldry, Anne-Christine; Braga Lagache, Sophie; Roma, Luca; Cohen, Sandra; Jaquet, Muriel; Brandt, Laura P.; Alshalalfa, Mohammed; Puca, Loredana; ... (2020). Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nature Communications, 11(1), p. 5549. Springer Nature 10.1038/s41467-020-19328-1
Thienger, Phillip; Rubin, Mark A. (2020). SETting Up for Epigenetic Regulation of Advanced Prostate Cancer. Cancer cell, 38(3), pp. 309-311. Cell Press 10.1016/j.ccell.2020.08.009
Lotan, Tamara L; Tomlins, Scott A; Bismar, Tarek A; Van der Kwast, Theodorus H; Grignon, David; Egevad, Lars; Kristiansen, Glen; Pritchard, Colin C; Rubin, Mark A; Bubendorf, Lukas (2020). Report From the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers. I. Molecular Biomarkers in Prostate Cancer. The American journal of surgical pathology, 44(7), e15-e29. Wolters Kluwer Health 10.1097/PAS.0000000000001450
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Pisapia, David J; Ohara, Kentaro; Bareja, Rohan; Wilkes, David C; Hissong, Erika; Croyle, Jaclyn A; Kim, Joon-Hyung; Saab, Jad; MacDonald, Theresa Y; Beg, Shaham; O'Reilly, Catherine; Kudman, Sarah; Rubin, Mark A; Elemento, Olivier; Sboner, Andrea; Greenfield, Jeffrey; Mosquera, Juan Miguel (2020). Fusions involving BCOR and CREBBP are rare events in infiltrating glioma. Acta neuropathologica communications, 8(1), p. 80. BioMed Central 10.1186/s40478-020-00951-4
Rubin, Mark; Largiadèr, Carlo; Staub, Timo (2020). Das Bern Center for Precision Medicine (BCPM). Schweizer Krebsbulletin / Bulletin suisse du cancer(01/20), pp. 48-50. Bern: Istituto oncologico della Svizzera Italiana
Reyna, Matthew A; Haan, David; Paczkowska, Marta; Verbeke, Lieven P C; Vazquez, Miguel; Kahraman, Abdullah; Pulido-Tamayo, Sergio; Barenboim, Jonathan; Wadi, Lina; Dhingra, Priyanka; Shrestha, Raunak; Getz, Gad; Lawrence, Michael S; Pedersen, Jakob Skou; Rubin, Mark Andrew; Wheeler, David A; Brunak, Søren; Izarzugaza, Jose M G; Khurana, Ekta; Marchal, Kathleen; ... (2020). Pathway and network analysis of more than 2500 whole cancer genomes. Nature communications, 11(1), p. 729. Nature Publishing Group 10.1038/s41467-020-14367-0
Rheinbay, Esther; Nielsen, Morten Muhlig; Abascal, Federico; Wala, Jeremiah A; Shapira, Ofer; Tiao, Grace; Hornshøj, Henrik; Hess, Julian M; Juul, Randi Istrup; Lin, Ziao; Feuerbach, Lars; Sabarinathan, Radhakrishnan; Madsen, Tobias; Kim, Jaegil; Mularoni, Loris; Shuai, Shimin; Lanzos, Andrés; Herrmann, Carl; Maruvka, Yosef E; Shen, Ciyue; ... (2020). Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. Nature, 578(7793), pp. 102-111. Springer Nature 10.1038/s41586-020-1965-x
Arriaga, Juan M.; Panja, Sukanya; Alshalalfa, Mohammed; Zhao, Junfei; Zou, Min; Giacobbe, Arianna; Madubata, Chioma J.; Kim, Jaime Yeji; Rodriguez, Antonio; Coleman, Ilsa; Virk, Renu K.; Hibshoosh, Hanina; Ertunc, Onur; Ozbek, Büşra; Fountain, Julia; Jeffrey Karnes, R.; Luo, Jun; Antonarakis, Emmanuel S.; Nelson, Peter S.; Feng, Felix Y.; ... (2020). A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance. Nature ancer, 1(11), pp. 1082-1096. Springer Nature 10.1038/s43018-020-00125-0
Beltran, Himisha; Hruszkewycz, Andrew; Scher, Howard I; Hildesheim, Jeffrey; Isaacs, Jennifer; Yu, Evan Y; Kelly, Kathleen; Lin, Daniel; Dicker, Adam; Arnold, Julia; Hecht, Toby; Wicha, Max; Sears, Rosalie; Rowley, David; White, Richard; Gulley, James L; Lee, John; Diaz Meco, Maria; Small, Eric J; Shen, Michael; ... (2019). The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance. Clinical cancer research, 25(23), pp. 6916-6924. American Association for Cancer Research 10.1158/1078-0432.CCR-19-1423
Persi, Erez; Prandi, Davide; Wolf, Yuri I; Pozniak, Yair; Barnabas, Georgina D; Levanon, Keren; Barshack, Iris; Barbieri, Christopher; Gasperini, Paola; Beltran, Himisha; Faltas, Bishoy M; Rubin, Mark A.; Geiger, Tamar; Koonin, Eugene V; Demichelis, Francesca; Horn, David (2019). Proteomic and genomic signatures of repeat instability in cancer and adjacent normal tissues. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(34), pp. 16987-16996. National Academy of Sciences NAS 10.1073/pnas.1908790116
Lou, Shaoke; Cotter, Kellie A.; Li, Tianxiao; Liang, Jin; Mohsen, Hussein; Liu, Jason; Zhang, Jing; Cohen, Sandra; Xu, Jinrui; Yu, Haiyuan; Rubin, Mark A.; Gerstein, Mark (2019). GRAM: A GeneRAlized Model to predict the molecular effect of a non-coding variant in a cell-type specific manner. PLoS genetics, 15(8), e1007860. Public Library of Science 10.1371/journal.pgen.1007860
Robinson, Brian D; Vlachostergios, Panagiotis J; Bhinder, Bhavneet; Liu, Weisi; Li, Kailyn; Moss, Tyler J; Bareja, Rohan; Park, Kyung; Tavassoli, Peyman; Cyrta, Joanna; Tagawa, Scott T; Nanus, David M; Beltran, Himisha; Molina, Ana M; Khani, Francesca; Miguel Mosquera, Juan; Xylinas, Evanguelos; Shariat, Shahrokh F; Scherr, Douglas S; Rubin, Mark A.; ... (2019). Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling. Nature Communications, 10(1), p. 2977. Springer Nature 10.1038/s41467-019-10873-y
Shen, Michael M; Rubin, Mark Andrew (2019). Prostate Cancer Research at the Crossroads. Cold Spring Harbor perspectives in medicine, 9(7) Cold Spring Harbor Laboratory Press 10.1101/cshperspect.a036277
Abida, Wassim; Cyrta, Joanna; Heller, Glenn; Prandi, Davide; Armenia, Joshua; Coleman, Ilsa; Cieslik, Marcin; Benelli, Matteo; Robinson, Dan; Van Allen, Eliezer M; Sboner, Andrea; Fedrizzi, Tarcisio; Mosquera, Juan Miguel; Robinson, Brian D; De Sarkar, Navonil; Kunju, Lakshmi P; Tomlins, Scott; Wu, Yi Mi; Nava Rodrigues, Daniel; Loda, Massimo; ... (2019). Genomic correlates of clinical outcome in advanced prostate cancer. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(23), pp. 11428-11436. National Academy of Sciences NAS 10.1073/pnas.1902651116
Augello, Michael A; Liu, Deli; Deonarine, Lesa D; Robinson, Brian D; Huang, Dennis; Stelloo, Suzan; Blattner, Mirjam; Doane, Ashley S; Wong, Elissa W P; Chen, Yu; Rubin, Mark A.; Beltran, Himisha; Elemento, Olivier; Bergman, Andries M; Zwart, Wilbert; Sboner, Andrea; Dephoure, Noah; Barbieri, Christopher E (2019). CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis. Cancer cell, 35(4), 603-617.e8. Cell Press 10.1016/j.ccell.2019.03.001
Lee, Rachel S; Zhang, Luxi; Berger, Adeline; Lawrence, Mitchell G; Song, Jiangning; Niranjan, Birunthi; Davies, Rebecca G; Lister, Natalie L; Sandhu, Shahneen K; Rubin, Mark A.; Risbridger, Gail P; Taylor, Renea A; Rickman, David S; Horvath, Lisa G; Daly, Roger J (2019). Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target. Neoplasia, 21(4), pp. 389-400. Elsevier 10.1016/j.neo.2019.02.005
Rubin, Mark A.; Demichelis, Francesca (2019). The Genomics of Prostate Cancer: A Historic Perspective. Cold Spring Harbor perspectives in medicine, 9(3) Cold Spring Harbor Laboratory Press 10.1101/cshperspect.a034942
Skvortsova, Ksenia; Masle-Farquhar, Etienne; Luu, Phuc-Loi; Song, Jenny Z; Qu, Wenjia; Zotenko, Elena; Gould, Cathryn M; Du, Qian; Peters, Timothy J; Colino-Sanguino, Yolanda; Pidsley, Ruth; Nair, Shalima S; Khoury, Amanda; Smith, Grady C; Miosge, Lisa A; Reed, Joanne H; Kench, James G; Rubin, Mark A.; Horvath, Lisa; Bogdanovic, Ozren; ... (2019). DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns. Cancer cell, 35(2), 297-314.e8. Cell Press 10.1016/j.ccell.2019.01.004
Beltran, Himisha; Oromendia, Clara; Danila, Daniel C; Montgomery, Bruce; Hoimes, Christopher; Szmulewitz, Russell Z; Vaishampayan, Ulka; Armstrong, Andrew J; Stein, Mark; Pinski, Jacek; Mosquera, Juan M; Sailer, Verena; Bareja, Rohan; Romanel, Alessandro; Gumpeni, Naveen; Sboner, Andrea; Dardenne, Etienne; Puca, Loredana; Prandi, Davide; Rubin, Mark A.; ... (2019). A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers. Clinical cancer research, 25(1), pp. 43-51. American Association for Cancer Research 10.1158/1078-0432.CCR-18-1912
Fernandez, Evan M; Eng, Kenneth; Beg, Shaham; Beltran, Himisha; Faltas, Bishoy M; Mosquera, Juan Miguel; Nanus, David M; Pisapia, David J; Rao, Rema A; Robinson, Brian D; Rubin, Mark A.; Elemento, Olivier; Sboner, Andrea; Shah, Manish A; Song, Wei (2019). Cancer-Specific Thresholds Adjust for Whole Exome Sequencing-based Tumor Mutational Burden Distribution. JCO precision oncology, 3 American Society of Clinical Oncology 10.1200/PO.18.00400
Karkampouna, Sofia; Grosjean, Joël; Klima, Irena; Genitsch, Vera; Sboner, A.; K. Y. Ng, C.; De Filippo, M.R.; Piscuoglio, S.; Spahn, M.; Rubin, Mark Andrew; Thalmann, G.N.; Kruithof-de Julio, Marianna (2019). Establishment of an androgen-sensitive patient derived xenograft model of prostate cancer. European Urology Supplements, 18(1), e1154. Elsevier 10.1016/S1569-9056(19)30831-0
Boysen, Gunther; Rodrigues, Daniel N; Rescigno, Pasquale; Seed, George; Dolling, David; Riisnaes, Ruth; Crespo, Mateus; Zafeiriou, Zafeiris; Sumanasuriya, Semini; Bianchini, Diletta; Hunt, Joanne; Moloney, Deirdre; Perez-Lopez, Raquel; Tunariu, Nina; Miranda, Susana; Figueiredo, Inês; Ferreira, Ana; Christova, Rossitza; Gil, Veronica; Aziz, Sara; ... (2018). SPOP-Mutated/CHD1-Deleted Lethal Prostate Cancer and Abiraterone Sensitivity. Clinical cancer research, 24(22), pp. 5585-5593. American Association for Cancer Research 10.1158/1078-0432.CCR-18-0937
Cotter, Kellie Anne; Rubin, Mark Andrew (2018). Sequence of events in prostate cancer. Nature, 560(7720), pp. 557-559. Macmillan Journals Ltd. 10.1038/d41586-018-06029-5
Hopkins, Benjamin D; Pauli, Chantal; Du, Xing; Wang, Diana G; Li, Xiang; Wu, David; Amadiume, Solomon C; Goncalves, Marcus D; Hodakoski, Cindy; Lundquist, Mark R; Bareja, Rohan; Ma, Yan; Harris, Emily M; Sboner, Andrea; Beltran, Himisha; Rubin, Mark Andrew; Mukherjee, Siddhartha; Cantley, Lewis C (2018). Suppression of insulin feedback enhances the efficacy of PI3K inhibitors. Nature, 560(7719), pp. 499-503. Macmillan Journals Ltd. 10.1038/s41586-018-0343-4
Triscott, Joanna; Rubin, Mark A. (2018). Prostate Power Play: Does Accelerate -Deficient Cancer Progression? Cancer discovery, 8(6), pp. 682-685. American Association for Cancer Research 10.1158/2159-8290.CD-18-0369
Mateo, Joaquin; Cheng, Heather H; Beltran, Himisha; Dolling, David; Xu, Wen; Pritchard, Colin C; Mossop, Helen; Rescigno, Pasquale; Perez-Lopez, Raquel; Sailer, Verena; Kolinsky, Michael; Balasopoulou, Ada; Bertan, Claudia; Nanus, David M; Tagawa, Scott T; Thorne, Heather; Montgomery, Bruce; Carreira, Suzanne; Sandhu, Shahneen; Rubin, Mark Andrew; ... (2018). Clinical Outcome of Prostate Cancer Patients with Germline DNA Repair Mutations: Retrospective Analysis from an International Study. European urology, 73(5), pp. 687-693. Elsevier 10.1016/j.eururo.2018.01.010
Sailer, Verena; Schiffman, Marc H; Kossai, Myriam; Cyrta, Joanna; Beg, Shaham; Sullivan, Brian; Pua, Bradley B; Lee, Kyungmouk Steve; Talenfeld, Adam D; Nanus, David M; Tagawa, Scott T; Robinson, Brian D; Rao, Rema A; Pauli, Chantal; Bareja, Rohan; Beltran, Luis S; Sigaras, Alexandros; Eng, Kenneth Wa; Elemento, Olivier; Sboner, Andrea; ... (2018). Bone biopsy protocol for advanced prostate cancer in the era of precision medicine. Cancer, 124(5), pp. 1008-1015. John Wiley & Sons 10.1002/cncr.31173
Gillessen, Silke; Attard, Gerhardt; Beer, Tomasz M; Beltran, Himisha; Bossi, Alberto; Bristow, Rob; Carver, Brett; Castellano, Daniel; Chung, Byung Ha; Clarke, Noel; Daugaard, Gedske; Davis, Ian D; de Bono, Johann; Borges Dos Reis, Rodolfo; Drake, Charles G; Eeles, Ros; Efstathiou, Eleni; Evans, Christopher P; Fanti, Stefano; Feng, Felix; ... (2018). Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017. European urology, 73(2), pp. 178-211. Elsevier 10.1016/j.eururo.2017.06.002
Shoag, Jonathan; Liu, Deli; Blattner, Mirjam; Sboner, Andrea; Park, Kyung; Deonarine, Lesa; Robinson, Brian D; Mosquera, Juan Miguel; Chen, Yu; Rubin, Mark Andrew; Barbieri, Christopher E (2018). SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG. Journal of clinical investigation, 128(1), pp. 381-386. American Society for Clinical Investigation 10.1172/JCI96551
McNair, Christopher; Xu, Kexin; Mandigo, Amy C; Benelli, Matteo; Leiby, Benjamin; Rodrigues, Daniel; Lindberg, Johan; Gronberg, Henrik; Crespo, Mateus; De Laere, Bram; Dirix, Luc; Visakorpi, Tapio; Li, Fugen; Feng, Felix Y; de Bono, Johann; Demichelis, Francesca; Rubin, Mark Andrew; Brown, Myles; Knudsen, Karen E (2018). Differential impact of RB status on E2F1 reprogramming in human cancer. Journal of clinical investigation, 128(1), pp. 341-358. American Society for Clinical Investigation 10.1172/JCI93566
D'Alfonso, Timothy M; Subramaniyam, Shivakumar; Ginter, Paula S; Mosquera, Juan Miguel; Croyle, Jaclyn; Liu, Yi-Fang; Rubin, Mark Andrew; Shin, Sandra J (2018). Characterization of CD34-deficient myofibroblastomas of the breast. The breast journal, 24(1), pp. 55-61. Wiley 10.1111/tbj.12835
Rubin, Mark Andrew; Demichelis, Francesca (2018). The Genomics of Prostate Cancer: emerging understanding with technologic advances. Modern pathology, 31(S1), S1-11. Nature Publishing Group 10.1038/modpathol.2017.166
Shukla, Shipra; Cyrta, Joanna; Murphy, Devan A; Walczak, Edward G; Ran, Leili; Agrawal, Praveen; Xie, Yuanyuan; Chen, Yuedan; Wang, Shangqian; Zhan, Yu; Li, Dan; Wong, Elissa W P; Sboner, Andrea; Beltran, Himisha; Mosquera, Juan Miguel; Sher, Jessica; Cao, Zhen; Wongvipat, John; Koche, Richard P; Gopalan, Anuradha; ... (2017). Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance. Cancer cell, 32(6), 792-806.e7. Cell Press 10.1016/j.ccell.2017.10.008
Lee, D; Fontugne, J; Gumpeni, N; Park, K; MacDonald, T Y; Robinson, B D; Sboner, A; Rubin, Mark Andrew; Mosquera, J M; Barbieri, C E (2017). Molecular alterations in prostate cancer and association with MRI features. Prostate cancer and prostatic diseases, 20(4), pp. 430-435. Nature 10.1038/pcan.2017.33
Pauli, C; Moch, H; Rubin, Mark Andrew (2017). [Establishment of a living biobank : Improved guidance of precision cancer care with in vitro and in vivo cancer models]. Der Pathologe, 38(Suppl 2), pp. 160-168. Springer 10.1007/s00292-017-0346-1
Wilkes, David C; Sailer, Verena; Xue, Hui; Cheng, Hongwei; Collins, Colin C; Gleave, Martin; Wang, Yuzhuo; Demichelis, Francesca; Beltran, Himisha; Rubin, Mark Andrew; Rickman, David S (2017). A germline FANCA alteration that is associated with increased sensitivity to DNA damaging agents. Cold Spring Harbor molecular case studies, 3(5) Cold Spring Harbor Laboratory Press 10.1101/mcs.a001487
Dai, Xiangpeng; Gan, Wenjian; Li, Xiaoning; Wang, Shangqian; Zhang, Wei; Huang, Ling; Liu, Shengwu; Zhong, Qing; Guo, Jianping; Zhang, Jinfang; Chen, Ting; Shimizu, Kouhei; Beca, Francisco; Blattner, Mirjam; Vasudevan, Divya; Buckley, Dennis L; Qi, Jun; Buser, Lorenz; Liu, Pengda; Inuzuka, Hiroyuki; ... (2017). Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. Nature medicine, 23(9), pp. 1063-1071. Nature Publishing Group 10.1038/nm.4378
Minciacchi, V R; Zijlstra, A; Rubin, Mark Andrew; Di Vizio, D (2017). Extracellular vesicles for liquid biopsy in prostate cancer: where are we and where are we headed? Prostate cancer and prostatic diseases, 20(3), pp. 251-258. Nature 10.1038/pcan.2017.7
Huang, Franklin W; Mosquera, Juan Miguel; Garofalo, Andrea; Oh, Coyin; Baco, Maria; Amin-Mansour, Ali; Rabasha, Bokang; Bahl, Samira; Mullane, Stephanie A; Robinson, Brian D; Aldubayan, Saud; Khani, Francesca; Karir, Beerinder; Kim, Eejung; Chimene-Weiss, Jeremy; Hofree, Matan; Romanel, Alessandro; Osborne, Joseph R; Kim, Jong Wook; Azabdaftari, Gissou; ... (2017). Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations. Cancer discovery, 7(9), pp. 973-983. American Association for Cancer Research 10.1158/2159-8290.CD-16-0960
Wang, Hui; Barbieri, Christopher E; He, Jintang; Gao, Yuqian; Shi, Tujin; Wu, Chaochao; Schepmoes, Athena A; Fillmore, Thomas L; Chae, Sung-Suk; Huang, Dennis; Mosquera, Juan Miguel; Qian, Wei-Jun; Smith, Richard D; Srivastava, Sudhir; Kagan, Jacob; Camp, David G; Rodland, Karin D; Rubin, Mark Andrew; Liu, Tao (2017). Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics. Journal of translational medicine, 15(1), p. 175. BioMed Central 10.1186/s12967-017-1276-7
Sanda, Martin G; Feng, Ziding; Howard, David H; Tomlins, Scott A; Sokoll, Lori J; Chan, Daniel W; Regan, Meredith M; Groskopf, Jack; Chipman, Jonathan; Patil, Dattatraya H; Salami, Simpa S; Scherr, Douglas S; Kagan, Jacob; Srivastava, Sudhir; Thompson, Ian M; Siddiqui, Javed; Fan, Jing; Joon, Aron Y; Bantis, Leonidas E; Rubin, Mark Andrew; ... (2017). Association Between Combined TMPRSS2:ERG and PCA3 RNA Urinary Testing and Detection of Aggressive Prostate Cancer. JAMA oncology, 3(8), pp. 1085-1093. American Medical Association 10.1001/jamaoncol.2017.0177
Dhingra, Priyanka; Martinez-Fundichely, Alexander; Berger, Adeline; Huang, Franklin W; Forbes, Andre Neil; Liu, Eric Minwei; Liu, Deli; Sboner, Andrea; Tamayo, Pablo; Rickman, David S; Rubin, Mark Andrew; Khurana, Ekta (2017). Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network. Genome biology, 18(1), p. 141. BioMed Central Ltd. 10.1186/s13059-017-1266-3
Zou, Min; Toivanen, Roxanne; Mitrofanova, Antonina; Floch, Nicolas; Hayati, Sheida; Sun, Yanping; Le Magnen, Clémentine; Chester, Daniel; Mostaghel, Elahe A; Califano, Andrea; Rubin, Mark Andrew; Shen, Michael M; Abate-Shen, Cory (2017). Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-Resistant Prostate Cancer. Cancer discovery, 7(7), pp. 736-749. American Association for Cancer Research 10.1158/2159-8290.CD-16-1174
O'Malley, Padraic G; Nguyen, Daniel P.; Al Hussein Al Awamlh, Bashir; Wu, Guojiao; Thompson, Ian M; Sanda, Martin; Rubin, Mark Andrew; Wei, John T; Lee, Richard; Christos, Paul; Barbieri, Christopher; Scherr, Douglas S (2017). Racial Variation in the Utility of Urinary Biomarkers PCA3 and T2ERG in a Large Multicenter Study. The journal of urology, 198(1), pp. 42-49. Elsevier 10.1016/j.juro.2017.01.058
Romanel, Alessandro; Garritano, Sonia; Stringa, Blerta; Blattner, Mirjam; Dalfovo, Davide; Chakravarty, Dimple; Soong, David; Cotter, Kellie Anne; Petris, Gianluca; Dhingra, Priyanka; Gasperini, Paola; Cereseto, Anna; Elemento, Olivier; Sboner, Andrea; Khurana, Ekta; Inga, Alberto; Rubin, Mark Andrew; Demichelis, Francesca (2017). Inherited determinants of early recurrent somatic mutations in prostate cancer. Nature communications, 8(1), p. 48. Nature Publishing Group 10.1038/s41467-017-00046-0
Rickman, David S; Beltran, Himisha; Demichelis, Francesca; Rubin, Mark Andrew (2017). Biology and evolution of poorly differentiated neuroendocrine tumors. Nature medicine, 23(6), pp. 664-673. Nature Publishing Group 10.1038/nm.4341
Huang, Linda; Fernandes, Helen; Zia, Hamid; Tavassoli, Peyman; Rennert, Hanna; Pisapia, David; Imielinski, Marcin; Sboner, Andrea; Rubin, Mark Andrew; Kluk, Michael; Elemento, Olivier (2017). The cancer precision medicine knowledge base for structured clinical-grade mutations and interpretations. Journal of the American Medical Informatics Association, 24(3), pp. 513-519. Oxford University Press 10.1093/jamia/ocw148
Imielinski, Marcin; Rubin, Mark Andrew (2017). Prostate cancer: Clinical hallmarks in whole cancer genomes. Nature reviews - clinical oncology, 14(5), pp. 265-266. Nature Publishing Group 10.1038/nrclinonc.2017.45
Pauli, Chantal; Hopkins, Benjamin D; Prandi, Davide; Shaw, Reid; Fedrizzi, Tarcisio; Sboner, Andrea; Sailer, Verena; Augello, Michael; Puca, Loredana; Rosati, Rachele; McNary, Terra J; Churakova, Yelena; Cheung, Cynthia; Triscott, Joanna Catherine Caprio; Pisapia, David; Rao, Rema; Mosquera, Juan Miguel; Robinson, Brian; Faltas, Bishoy M; Emerling, Brooke E; ... (2017). Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine. Cancer discovery, 7(5), pp. 462-477. American Association for Cancer Research 10.1158/2159-8290.CD-16-1154
Sailer, Verena; Pauli, Chantal; Merzier, Elyze C; Mosquera, Juan Miguel; Beltran, Himisha; Rubin, Mark Andrew; Rao, Rema A (2017). On-site Cytology for Development of Patient-Derived Three-dimensional Organoid Cultures - A Pilot Study. Anticancer research, 37(4), pp. 1569-1573. International Inst. of Anticancer Research 10.21873/anticanres.11486
Blattner, Mirjam; Liu, Deli; Robinson, Brian D; Huang, Dennis; Poliakov, Anton; Gao, Dong; Nataraj, Srilakshmi; Deonarine, Lesa D; Augello, Michael A; Sailer, Verena; Ponnala, Lalit; Ittmann, Michael; Chinnaiyan, Arul M; Sboner, Andrea; Chen, Yu; Rubin, Mark Andrew; Barbieri, Christopher E (2017). SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling. Cancer cell, 31(3), pp. 436-451. Cell Press 10.1016/j.ccell.2017.02.004
Mateo, Joaquin; Boysen, Gunther; Barbieri, Christopher E; Bryant, Helen E; Castro, Elena; Nelson, Pete S; Olmos, David; Pritchard, Colin C; Rubin, Mark Andrew; de Bono, Johann S (2017). DNA Repair in Prostate Cancer: Biology and Clinical Implications. European urology, 71(3), pp. 417-425. Elsevier 10.1016/j.eururo.2016.08.037
Barbieri, Christopher E; Chinnaiyan, Arul M; Lerner, Seth P; Swanton, Charles; Rubin, Mark Andrew (2017). The Emergence of Precision Urologic Oncology: A Collaborative Review on Biomarker-driven Therapeutics. European urology, 71(2), pp. 237-246. Elsevier 10.1016/j.eururo.2016.08.024
Villers, Arnauld; Rubin, Mark Andrew (2017). Re: Prognostic Significance of Percentage and Architectural Types of Contemporary Gleason Pattern 4 Prostate Cancer in Radical Prostatectomy. European urology, 71(2), p. 301. Elsevier 10.1016/j.eururo.2016.09.017
Mu, Ping; Zhang, Zeda; Benelli, Matteo; Karthaus, Wouter R; Hoover, Elizabeth; Chen, Chi-Chao; Wongvipat, John; Ku, Sheng-Yu; Gao, Dong; Cao, Zhen; Shah, Neel; Adams, Elizabeth J; Abida, Wassim; Watson, Philip A; Prandi, Davide; Huang, Chun-Hao; de Stanchina, Elisa; Lowe, Scott W; Ellis, Leigh; Beltran, Himisha; ... (2017). SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer. Science, 355(6320), pp. 84-88. American Association for the Advancement of Science 10.1126/science.aah4307
Bishop, Jennifer L; Thaper, Daksh; Vahid, Sepideh; Davies, Alastair; Ketola, Kirsi; Kuruma, Hidetoshi; Jama, Randy; Nip, Ka Mun; Angeles, Arkhjamil; Johnson, Fraser; Wyatt, Alexander W; Fazli, Ladan; Gleave, Martin E; Lin, Dong; Rubin, Mark Andrew; Collins, Colin C; Wang, Yuzhuo; Beltran, Himisha; Zoubeidi, Amina (2017). The Master Neural Transcription Factor BRN2 Is an Androgen Receptor-Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer. Cancer discovery, 7(1), pp. 54-71. American Association for Cancer Research 10.1158/2159-8290.CD-15-1263
